基本情况

张有成，兰州大学第二医院教授、主任医师。兰州大学第二医院副院长、消化肿瘤重点实验室副主任、消化系疾病临床医学中心副主任、胆胰外科主任、肝胆胰外科研究所所长、甘肃省卫生厅肝胆胰外科重点学科负责人、甘肃省领军人才，甘肃省卫生厅学术技术带头人，《中华医学杂志》、《中华普通外科杂志》、《临床肝胆病杂志》、《器官移植》、《兰州大学学报（医学版）》编委，中华医学会肠内肠外营养学分会委员，甘肃省中西医结合学会副会长，甘肃省医学会常务理事，甘肃省医师协会理事兼外科医师分会副会长，甘肃省医学会肠内肠外营养专业委员会主任委员、肿瘤专业委员会副主任委员。

 

研究领域

消化系统肿瘤、肝胆胰外科

 

教育背景

2004年 博士，北京大学

1995年 硕士，北京医科大学

1984年 学士，西安医科大学

 

论文发表

  1. Zhang Youcheng, Leng Xisheng, Zhu Jiye, et al. Alpha-1 Adrenergic Receptors in Plasma Membranes of Cirrhotic Patients with Portal Hypertension:A Quantitative Study. Chin Med J 1998; 111(6):507-9
  2. Zhang YC, Wang XP, Zhang LY, et al. Effect of blocking IGF-I receptor on growth of human hepatocellular carcinoma cells. World J Gastroenterol 2006; 12(25): 3977-3982
  3. Zhang YC, Zhang YW. Growth inhibition of insulin-like growth factor I receptor monoclonal antibody to human colorectal cancer cells. Can Invest 2008; 26(3):230-236
  4. Xiaojun Yang, Youcheng Zhang, Lingyi Zhang, Lin Zhang, Jie Mao. Silencing alpha-fetoprotein expression induces growth arrest and apoptosis in human hepatocellular cancer cell. Cancer Letters 2008; 271 (2) :281–293
  5. Yang SH, Yang KH, Li YP, Zhang YC, et al. Breast conservatuon therapy for stage I or stage II breast cancer: a meta-analysis of randomized controlled trials. Ann Oncol 2008;19(6):1039-1044
  6. Xu Wang, Jun Qian, Yanchao Ma, Guoxin Nan, Shuanke Wang, Yayi Xia, Youcheng Zhang. Ependymal cell proliferation and apoptosis following acute spinal cord injury in the adult rat. Neural Regeneration Research 2008; 3(10):1051-5
  7. Sun Hu Yang, You Cheng Zhang*, Ke Hu Yang, You Ping Li, Xiao Dong He, Jin Hui Tian, Ting Hong Lv, Ying Hua Hui, Neel Sharma.. An evidence-based medicine review of lymphadenectomy extent for gastric cancer. Am J Surg. 2009; 197(2):246-251
  8. Lin Zhang, You-cheng Zhang, Ling-yi Zhang and Xiaojun Yang. Lupeol, a triterpene, induced growth inhibition and apoptosis in human hepatocellular carcinoma cell lines. Cancer investigation, 2009; 27(2):163-170
  9. You Cheng Zhang, Sun Hu Yang, Jian Gao, and Neel Sharma. The Surgical Intervention for Noninsulin-Dependent Diabetes Mellitus. The Endocrinologist 2009; 19(5):220-221
  10. Xu Wang, Zhengyi Sun, Jing Wang, Guoxin Nan ,Yanchao Ma, Shuanke Wang , Yayi Xia, Youcheng Zhang. X-Ray Exposure Induces Apoptosis of Some Proliferative Epidermal Cells Following Traumatic Spinal Cord Injury in Adult Rats. International Journal of Neuroscience 2009; 119( 1 ):141-154
  11. Hai Li Shen, Yu-Feng Xie, Hua Han, Ya-Yi Xia, You-Cheng Zhang, Cui-Fang Wang, Jing Wang. Formalin-induced astrocyte glutamate-glutamine cycle involved in rat spinal cord central sensitization. Neural Regeneration Research (NRR) 2009,4(11),918- 922
  12. Zhi Cheng Lv, Qiang Ma, You Cheng Zhang, Jing Ming Wang, Tuan Jie Che, Xiang Hui Wang. Inhibiting tumor growth of colorectal cancer by blocking the expression of VEGFR-3 using interference vector-based RNA interference. International Journal of Molecular Medicine, 2010; 25:59-64
  13. Sunhu Y, YC Zhang. Commentary for an evidence-based medicine review of lymphadenectomy extent for gastric cancer. Am J Surg. 2010 Jun 28. [Epub ahead of print]
  14. Shan Deng, Xiaojun Yang, Heini Lassus, Shun Liang, Sippy Kaur, Qunrui Ye, Chunsheng Li,Li-Ping Wang, Katherine F. Roby, Sandra Orsulic, Denise C. Connolly, Youcheng Zhang, Kathleen Montone, Ralf Bu¨ tzow, George Coukos1, Lin Zhang. Distinct Expression Levels and Patterns of Stem Cell Marker, Aldehyde Dehydrogenase Isoform 1 (ALDH1), in Human Epithelial Cancers. PLoS ONE 2010; 5(4): e10277. www.plosone.org
  15. Yang X, Lin X, Zhong X, Kaur S, Li N, Liang S, Lassus H, Wang L, Katsaros D, Montone K, Zhao X, Zhang Y, Bützow R, Coukos G, Zhang L: Double negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells. Cancer research. 2010 november; 70(22): 9463-72
  16. Hai Peng Liu, Xiao Feng Shi, You Cheng Zhang, Zhong Xin Li, Lin Zhang and Zhe Yuan Wang. Quantitative Analysis of Quercetin in Euphorbia helioscopia L by RP-HPLC. Cell Biochemistry and Biophysics (DOI: 10.1007/s12013-011-9161-0)
  17. Jie Mao, Mei Li, Ai Lin Song, Xiao Chen and You Cheng Zhang. The extrahepatic bile duct stricture mimicking a hilar cholangiocarcinoma: case report and review of the literature. European Journal of Radiology Extra 77 (2011) e55–e58
  18. Hai Peng Liu, You Cheng Zhang, Yu Long Zhang, Lan Ning Yin, Jun Wang. Drain versus No-Drain after Gastrectomy for Patients with Advanced Gastric Cancer: Systematic Review and Meta-Analysis. Dig Surg 2011;28:178–189
  19. MAO Jie, ZHANG Lin, SONG Ai-lin, CHEN Xiao and ZHANG You-cheng. Effect of ulinastatin donor-pretreatment on liver graft during cold preservation in rats. Chin Med J 2011;124(4):574-580