基本情况

王久存，复旦大学生命科学学院教授。2007年至2008年在美国德克萨斯大学休斯敦健康科学中心进行访问研究。

研究领域

肺癌等肿瘤致病机理的遗传学及表观遗传学研究、硬皮病等自身免疫性疾病的基因组学研究及分子致病机理研究

教育背景

1999年 博士，日本福井大学生物应用化学专业

1991年 硕士，复旦大学生命科学学院

1988年 学士，复旦大学生物学系生物化学专业

论文发表

1. Lin Q, Peng Q, Yao F, Pan XF, Xiong LW, Wang Y, Geng JF, Han BH, Bao GL, Yang Y, Wang X, Jin L, Guo W, Wang JC*. A classification method based on principal components of SELDI spectra to diagnose of lung adenocarcinoma. PLoS ONE. Accepted
2. Wang JC, Sonnylal S, Arnett FC, de Crombrugghe B, Zhou X. Attenuation of gene expression of extracellular matrix elements with siRNAs of Sparc and Ctgf in cultured skin fibroblasts from Ctgf transgenic mice. International Journal of Immunopathology and Pharmacology. 2011; 24(3): 595-601
3. Liu Q, Yao F, Wang M, Zhou B, Cheng H, Wang W, Jin L, Lin Q, Wang JC*. Novel human BTB/POZ domain-containing zinc finger protein ZBTB1 inhibits transcriptional activities of CRE. Mol Cell Biochem. 2011; 357(1-2): 405-14
4. Zhang J#, Wang J#, Ma Y, Du W, Zhao S, Zhang Z, Zhang X, Liu Y, Xiao H, Wang H, Jin L, Liu J. A Novel Splicing Mutation Alters DSPP Transcription and Leads to Dentinogenesis Imperfecta Type II. PLoS ONE. 2011; 6(11): e27982
5. Wang JC, Lai S, Guo X, Zhang X, de Crombrugghe B, Arnett FC, Zhou X. Attenuation of fibrosis in vitro and in vivo with Sparc siRNA. Arthritis Res Ther.2010; 12(2): R60
6. Wang YL, Wang JC*, Wu Y, Zhang L, Huang CP, Shen Q, Zhu YX, Li DS, Ji QH*. Incidentally simultaneous occurrence of RET/PTC, H4-PTEN and BRAFmutation in papillary thyroid carcinoma. Cancer Letters. 2008. 34(1): 77-81
7. Wang JC, Su CC, Xu JB, Chen LZ, Hu XH, Wang GY, Bao Y, Huang Q, Fu SB, Li P, Lu CQ, Zhang RM, Luo ZW. A novel microdeletion in the transforming growth factor β type II receptor gene(TGFBR2) is associated with giant and large cell variants of non-small cell lung carcinoma. Genes, Chromosomes and Cancer. 2007.46: 192-201
8. Xu JB, Bao Y, Liu X, Liu Y, Huang HD, Wang JC*.Defective expression of transforming growth factor-β type II receptor (TGFBR2) in the large cell variant of non-small cell lung carcinoma. Lung Cancer. 2007. 58(1): 36-43
9. Wang JC, Wang M, Zhang R, Zhao Z, Chen J, and Luo Z. A chemiluminescence-based assessment of androgen-binding activity in a large pedigree affected with androgen insensitivity syndrome. Luminescence. 2007. 22 (4): 370-378