基本情况

刘明,遗传学理学博士,首都师范大学生命科学学院副教授。中国化学会公共安全化学专业委员会委员。多年教学工作中,曾承担本科生及硕士研究生理论有机化学、药物化学、基因工程、蛋白质工程、细胞及分子生物学实验、生物技术综合实验等课程。科研工作,博士研究生期间主要从事镇痛药物分子设计、合成及生物活性研究,作为骨干成员参加了国家自然科学基金海外青年学者合作研究项目、国家自然科学基金面上项目;主持国家某部委实验室开放基金项目。201512月,获得省部级科技进步一等奖,排名第三。

 

教育背景

2007年至2013年 遗传学博士,首都师范大学生命科学学院

2000年至2003年 植物学硕士,首都师范大学生命科学学院

1986年至1990年 生物学学士,首都师范大学生命科学学院

 

工作经历 

1997年至今   讲师、副教授,首都师范大学生命科学学院

1990年至1997年 工程师,北京市发酵工业研究所 

              

论文发表

  1. Liu M, Liu XL, Wan P, Wu QS, Hu WX. Determination of structure-activity relationships between fentanyl analogs and human μ-opioid receptor based on active binding site models. Neural Regen Res, 2011, 6(4): 267-276.(SCI)
  2. Liu M, Wu QS, Hu WX. Pharmacophore screening on piperidinecarboxamides derivatives based on GALAHAD and CoMFA models. Chin J Chem, 2011, 29(6): 1075-1083.(SCI)
  3. Liu M, Sun ZG, Hu WX. Three-dimensional common-feature hypotheses for fentanyl derivatives. Neural Regen Res, 2012, 7(18): 1398-1405.(SCI)
  4. Li B, Liu M, Hu WX. Molecular docking and molecular dynamics simulations of fentanyl analogs binding to u-opioid receptors. Acta Phys-Chim Sin, 2010, 26 (1): 206-214. (SCI)
  5. Liu M, Hu WX. Design, synthesis and biological evaluation of novel fentanyl analogues as agonist of μ-opioid receptor. Applied Mechanics & Materials.2012, Vol.217-219: 937-940.(EI)
  6. Liu M, Hu WX. Recent progress of microwave irradiation in synthesis and diagnosis treatment. Advanced Materials Research, 2013, 616-618(22): 1711-1716.(EI)
  7. Liu M, Liu JQ, Liu XL, Qiu MH, Hu W X. Molecular docking of G. Pentaphyllum to LXRs receptors and agonist screening. The 2nd International conference on Artificial Intelligence, Management Science and Electronic Commerce, 2011, 8: 6684-6687. (EI)
  8. Liu M, Wan P, Hu WX. Protein sequence alignment of target for fentanyl analgesics, μ-opioid receptor and its analysis. The Proceeding of the Second International Conference on Information Science and Engineering (ICISE 2010), IEEE CPS Press, 2010: 6777-6780.(EI)  
  9. Liu M, Hu WX. Cell cycle checkpoint signaling through the ATR and ATM kinases. Proceeding of the Second International Conference on Information Science and Engineering, IEEE Computer Sciety Conference Publishing Service, 2010: 7244-7247. (EI)
  10. Liu M, Hu WX. Liu XL. Molecular docking and 3D-QSAR studies of 4-phenylpiperidine derivatives as μ-opioid agonists. Advanced Material Research, 2012, 361-363: 263-267. (EI)           
  11. Hu WX, Liu M, Gong YL. Research on mechanism of microwave catalysis organic reactions and its applications in medicinal chemistry. Piezoelectrics and Acoustooptics, 2008, 30(2s): 9-11.(EI)
  12. Liu M, Hu WX. Highly efficient microwave-assisted and ultrasonic-assisted extraction. Proceedings of 2010 the Second China Energy, Scientist Forum, Scientific Research Publishing, USA, 2010, 1: 98-101.(ISTP)
  13. Liu M, Kong B, He FD, Hu WX. The applications of microwave irradiation as greener and convenient procedure in organic synthesis. Proceedings of 2010 the Second China Energy, Scientist Forum, Scientific Research Publishing, USA, 2010, 1: 94-97. (ISTP)
  14. Liu M, Li B, Hu WX. 3D QSAR of imidazoline-derived a2A-adrenergic ligands on the basis of molecular docking. Chemistry, 2010, 11: 989-994
  15. Liu M, Hu WX. Applications of immunoassay in targeted drug screening. Chinese Journal of Applied Chemistry. 2009, 26s(10): 110-114
  16. Liu M, Hu WX. The functional role of ATM in the cellular response to DNA damage. Front Chem Sci Eng, 2011, 5(2): 179-187. (included by Inspec, Scopus)
  17. Hu WX, Shi Y, Liu M, Li B, Wang HY. Study on Diels-Alder Reaction with Quantum. Chemistry, 2010, 73(9): 804-808
  18. Liu M, Peng XR, Liu JQ, Qiu M , Hu WX. The Applications of Microwave Catalysis in Organic Chemistry. Journal of Kunming University of Science and Technology, 2011, 36(8): 199-209
  19. 邵开元王乔刘明邢欣胡文祥,应用量子化学反应性指数评估化合物的亲核能力,化学通报,2014773):227-235
  20. 刘明胡文祥,爆炸性物质的测量测定技术方法,有机化学研究,201531):77-83
  21. 刘明胡文祥,细胞分子生物学实验教学改革,《教育创新:思考与行动——首都师范大学教学质量与教学改革研究文集(三)》,首都师范大学出版社,2009299-304
  22. 胡文祥刘明著,《阿片受体分子药学》,北京:化学工业出版社,20142月出版,
  23. 参编《反恐技术方略》主要编委,排名第三,北京:化学工业出版社,20138月出版。该书获得2014年度中国石油和化学工业优秀出版物一等奖
  24. 参编《比较化学-构筑通向分子药学的桥梁》主要编委,北京:化学工业出版社,20133月出版
  25. 参编《航天与健康》主要编委,北京:中国医药科技出版社,20143月出版