病毒性脑炎所致阵发性自主神经性不稳伴肌张力不全1例

Paroxysmal Autonomic Instability with Dystonia Induced by Viral Encephalitis: A Case Report

摘要: 目的：探讨病毒性脑炎所致阵发性自主神经性不稳伴肌张力不全(PAID)的临床特点及治疗对策。方法：回顾性分析本院收治的1例病毒性脑炎所致PAID的临床资料。结果：患儿出现阵发性躁动、发热、多汗、呼吸急促、心动过速、血压升高、肌张力障碍和抽搐症状，经联合用药治疗后，患儿逐步好转出院，随访1年半，四肢肌张力恢复正常，未遗留下严重后遗症状。结论：由病毒性脑炎所致的PAID较少见，应注意早期识别，积极控制PAID症状，宜尽早联合两种或两种以上药物治疗。

Abstract: Objective: To explore the clinical features and therapeutic strategy of Paroxysmal autonomic instability with dystonia (PAID) induced by viral encephalitis. Methods:The clinical data of one child with PAID induced by viral encephalitis diagnosed in our hospital was analyzed retrospectively. Results: The child presented with intermittent agitation, fever,diaphoresis, tachycardia,tachypnea, hypertension, extensor posturing and seizures.Through the treatment of combined drugs, the child was gradually improved and discharged.After a follow-up of one and a half years, themuscular tension of limbs returned to normal and there were not serious neurologic sequelae. Conclusion: The PAID induced by viral encephalitis is rare. Early recognition is of paramount importance to start treatment in an early stage and various drugs should be combined to alleviate PAID.