|
[1]
|
Hall, A. (1998) Rho GTPases and the actin cytoskeleton. Science, 279, 509-514.
|
|
[2]
|
Nakamura, F. (2013) FilGAP and its close relatives: A mediator of Rho-Rac antagonism that regulates cell morphology and migration. Biochemical Journal, 453, 17-25.
|
|
[3]
|
Doran, J.D., Liu, X., Taslimi, P., et al. (2004) New insights into the structure function relationships of Rho associated kinase: A thermodynamic and hydrodynamic study of the dimer to monomer transition and its kinetic implications. Biochemical Journal, 384, 255-262.
|
|
[4]
|
Catharine, A. and Bryan, B.A. (2011) Rho kinase proteins— Pleiotropic modulators of cell survival and apoptosis. Anticancer Research, 31, 3645-3657.
|
|
[5]
|
Naraoka, M., Munakata, A., Matsuda, N., Shimamura, N. and Ohkuma, H. (2013) Suppression of the Rho/Rho-Kinase pathway and prevention of cerebral vasospasm by combination treatment with statin and fasudil after subarachnoid hemorrhage in rabbit. Translational Stroke Research, 4, 368-374.
|
|
[6]
|
Heasman, S.J. and Ridley, A.J. (2008) Mammalian Rho GTPases: New insights into their functions from in vivo studies. Nature Reviews Molecular Cell Biology, 9, 690-701.
|
|
[7]
|
Diebold, B.A., Fowler, B., Lu, J., et al. (2004) Antagonistic cross talk between Rac and Cdc42 GTPases regulates generation of reactive oxygen species. The Journal of Biological Chemistry, 279, 28136-28142.
|
|
[8]
|
Sahai, E. and Marshall, C.J. (2002) Rho-GTPases and cancer. Nature Reviews Cancer, 2, 133-142.
|
|
[9]
|
Van Aelst, L. and D’Souza-Schorey, C. (1997) Rho GTPases and signalling networks. Genes & Development, 11, 2295-2322.
|
|
[10]
|
Takemoto, M., Sun, J., Hiroki, J., Shimokawa, H. and Liao, J.K. (2002) Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase. Circulation, 106, 57-62.
|
|
[11]
|
Joshi, A.D., Dimitropoulou, C., Thangjam, G., Snead, C. and Feldman, S. (2013) Hsp90 inhibitors prevent LPS-induced endothelial barrier dysfunction by disrupting RhoA signaling. American Journal of Respiratory Cell and Molecular Biology, 23, 4553.
|
|
[12]
|
Lees, K.R., Diener, H.C., Asplund, K., et al. (2003) UK 279, 276, a neutrophil inhibitory glycoprotein, in acute stroke: Tolerability and pharmacokinetics. Stroke, 34, 1704-1709.
|
|
[13]
|
Shi, J. and Wei, L. (2007) Rho kinase in the regulation of cell death and survival. Archivum Immunologiae et Therapia Experimentalis, 55, 61-75.
|
|
[14]
|
Shin, H.K., Salomone, S., Potts, E.M., et al. (2007) Rhokinase inhibition acutely augments blood flow in focal cerebral ischemia via endothelial mechanisms. Journal of Cerebral Blood Flow & Metabolism, 27, 998-1009.
|
|
[15]
|
Shibuya, M., Hirai, S., Seto, M., et al. (2005) Effects of fasudil in acute ischemic stroke: Results of a prospective placebo controlled double blind trial. Journal of the Neurological Sciences, 15, 31-39.
|
|
[16]
|
Wang, S., Lee, S.R., Guo, S.Z., et al. (2006) Reduction of tissue plasminogen activator induced matrix metalloproteinase9 by simvastatin in astrocytes. Stroke, 37, 1910-1912.
|
|
[17]
|
Rikitake, Y., Kim, H.H., Huang, Z., et al. (2005) Inhibition of Rhokinase (ROCK) leads to increased cerebral blood flow and stroke protection. Stroke, 36, 2251-2257.
|
|
[18]
|
刘康, 丁素菊, 吴涛, 等 (2011) Rho激酶抑制剂对大鼠脑缺血损伤的脑保护作用及S100B蛋白表达的影响. 临床神经病学杂志, 2, 111-113.
|