菜籽低聚肽抗肿瘤活性研究

Study on the Antitumor Activity of Rapeseed Low Poly Peptides

摘要: 本文以中国发明专利“菜籽低聚肽的制备方法及产品”(专利号：2007100533858)的产品为材料，研究了菜籽低聚肽的抗肿瘤活性。结果表明，菜籽低聚肽对S180肿瘤的生长具有抑制作用，同时明显提高荷瘤小鼠的免疫功能，使荷瘤小鼠血清中的SOD值升高和MDA值降低，提高荷瘤小鼠血清溶血素HCIgM的形成，增强巨噬细胞吞噬能力和迟发型超敏反应强度。

Abstract: In this paper, using China invention patent “rapeseed low poly peptides preparation method and products” (Patent No: 2007100533858) products as materials, the antitumor activity of the rapeseed low poly peptides was studied. The results showed that the rapeseed low poly peptides have inhibition to the growth of S180 tumor; at the same time significantly improve a tumor-burdened immune function of mice; rise SOD value and reduce MDA value of mice serum; improve the formation of serum hemolysin HCIgM of tumor-burdened mice; and enhance the ability of macrophage cell and delayed-type hypersensitivity intensity.