导致骨质疏松症的危险因素的分析研究
Analysis of Risk Factors Leading to Osteoporosis Research
DOI: 10.12677/MD.2014.42003, PDF, HTML, 下载: 2,895  浏览: 10,509  科研立项经费支持
作者: 朱红军, 路瀛, 林敏, 陈奕佳：苏州市姑苏区双塔街道社区卫生服务中心，苏州；袁晨曦, 邹俊：苏州大学附属第一医院，苏州
关键词: 骨质疏松症；危险因素；Osteoporosis； Risk Factors
摘要: 背景：老年人随年龄增长，骨量一般会逐渐减低，骨质疏松症是一种与增龄相关的疾病，同时也是一种与遗传和环境因素密切相关的疾病。目的：综述骨质疏松的相关危险因素。方法：计算机检索PubMed数据库(1984年1月至2014年3月)、万方数据(2002年1月至2014年3月)、CNKI 期刊全文数据库(2002年1月至2014年3月)中有关骨质疏松的数据。结果与结论：骨质疏松的危险因素主要有性别、年龄、种族、家族史、激素水平等不可控制的因素和饮食、疾病、用药和生活方式等可以控制的因素，积极控制以上危险因素，对于预防骨质疏松的异常具有重要意义。
Abstract: Background: The elderly increases with age, bone mass will generally reduce, osteoporosis is a disease associated with aging, but it is also a disease closely related to genetic and environmental factors. Objective: To review risk factors for osteoporosis. Method: Computer searches the osteoporosis-related data in PubMed database (January 1984 to March 2014), Wanfang data (from January 2002 to March 2014) and CNKI journal full-text database (from January 2002 to March 2014). Results and Conclusion: Major risk factors for osteoporosis include the uncontrollable factors such as gender, age, race, family history, hormone levels and controlled factors such as diseases, medications and diet and lifestyle; positive control over risk factors are important for exceptions to prevent osteoporosis.
文章引用：朱红军, 路瀛, 林敏, 陈奕佳, 袁晨曦, 邹俊. 导致骨质疏松症的危险因素的分析研究[J]. 医学诊断, 2014, 4(2): 15-20. http://dx.doi.org/10.12677/MD.2014.42003

参考文献

[1] [1] Kanis, J.A., Johnell, O., Odén, A., Dawson, A., De laet, C. and Jonsson, B. (2001) Ten year probabilities of osteoporotic fractures according to BMD and diagnosis thresholds. Osteoporosis International, 12, 989-995.
[2] Goldman, L., et al. (2012) Cecil medicine. 24th Edition, Saunders Elsevier, Philadelphia.
[3] Bope, E.T., et al. (2013) Conn’s current therapy. Saunders Elsevier, Philadelphia.
[4] Ferri, F.F. (2012) Ferri’s clinical advisor 2013: 5 Books in 1. Mosby Elsevier, Philadelphia.
[5] Kennel, K.A. (2013) Mayo Clinic, Rochester.
[6] Kanis, J.A., Johansson, H., Odén, A., Johnell, O., De Laet, C., Eisman, J.A., McCloskey, E.V., Mellström, D., Melton III, L.J., Pols, H.A., Reeve, J., Silman, A.J. and Tenenhouse, A. (2004) A familiy history of fracture and fracture risk: A meta-analysis. Bone, 35, 1029-1037.
[7] Kanis, J.A., Johansson, H., Odén, A., Johnell, O., De Laet, C., Melton III, L.J., Tenenhouse, A., Reeve, J., Silman, A.J., Pols, H., Eisman, J.A., McCliskey, E.V. and Mellström, D. (2004) A meta-analysis of prior corticosteroid use and fracture risk. Journal of Bone and Miner Research, 19, 893-899.
[8] Rosen, H.N. (2013) Denosumab for osteoporosis.
[9] (2013) Calcium. Office of Dietary Supplements, National Institutes of Health.
[10] Ask Mayo Expert (2012) Vitamin D deficiency. Mayo Foundation for Medical Education and Research, Rochester.
[11] Kanis, J.A., De Laet, C., Delmas, P., Garnero, P., Johansson, H., Johnell, O., Kriger, H., McCloskey, E.V., Mellstrom, D., Melton III, L.J., Odén, A., Pols, H., Reeve, J., Silman, A. and Tenehouse, A. (2004) A meta-analysis of previous fracture and fracture risk. Bone, 35, 375-382.
[12] (2013) Vitamin D. Office of Dietary Supplements, National Institutes of Health, 26.
[13] Zheng, J., Mao, X., Ling, J., He, Q., Quan, J. and Jiang, H. (2014) Association between serum level of magnesium and postmenopausal osteoporosis: A meta-analysis. Biological Trace Element Research, 159, 8-14.
[14] Mu, M., Wang, S.F., Sheng, J., Zhao, Y., Wang, G.X., Liu, K.Y., Hu, C.L., Tao, F.B. and Wang, H.L. (2014) Dietary patterns are associated with body mass index and bone mineral density in Chinese freshmen. Journal of the American College of Nutrition, 33, 120-128.
[15] Kim, N., Choi, H.R., Kim, S.W., Kim, B.S., Won, C.W. and Kim, S.Y. (2014) Association between bone mineral density and sleep duration in the Korean elderly population. Korean Journal of Family Medicine, 35, 90-97.
[16] Yang, D.H., Chiang, T.I., Chang, I.C., Lin, F.H., Wei, C.C. and Cheng, Y.W. (2014) Increased levels of circulating advanced glycation end-products in menopausal women with osteoporosis. International Journal of Medical Sciences, 11, 453-460.
[17] Yun, H., Curtis, J.R., Guo, L., Kilgore, M., Muntner, P., Saag, K., Matthews, R., Morrisey, M., Wright, N.C., Becker, D.J. and Delzell, E. (2014) Patterns and predictors of osteoporosis medication discontinuation and switching among medicare beneficiaries. BMC Musculoskeletal Disorders, 15, 112.
[18] Hsu, W.L., Chen, C.Y., Tsauo, J.Y. and Yang, R.S. (2014) Balance control in elderly people with osteoporosis. Journal of the Formosan Medical Association, 113, 334-339.
[19] Nevitt, M.C., Thompson, D.E., Black, D.M., Rubin, S.R., Ensrud, K., Yates, A.J. and Cummings, S.R. (2000) Effect of alendronate on limited-activity days and bed-disability days caused by back pain in postmenopausal women with existing vertebral fractures. Fracture Intervention Trial Research Group. JAMA Internal Medicine, 160, 77-85.
[20] Cummings, S.R., Black, D.M. and Rubin, S.M. (1989) Lifetime risks of hip, Colles’, or vertebral fracture and coronary heart disease among white postmenopausal women. JAMA Internal Medicine, 149, 2445-2448.
[21] Harvey, N., Dennison, E. and Cooper, C. (2010) Osteoporosis: Impact on health and economics. Nature Reviews Rheumatology, 6, 99-105.
[22] Oleksik, A., Lips, P., Dawson, A., Minshall, M.E., Shen, W., Cooper, C. and Kanis, J. (2000) Health-related quality of life in postmenopausal women with low BMD with or without prevalent vertebral fractures. Journal of Bone and Mineral Research, 15, 1384-1392.
[23] Nevitt, M.C., Ettinger, B., Black, D.M., Stone, K., Jamal, S.A., Ensrud, K., Segal, M., Genant, H.K. and Cummings, S.R. (1998) The association of radiographically detected vertebral fractures with back pain and function: A prospective study. Annals of Internal Medicine, 128, 793-800.
[24] Ensrud, K.E., Thompson, D.E., Cauley, J.A., Nevitt, M.C., Kado, D.M., Hochberg, M.C., Santora II, A.C. and Black, D.M. (2000) Prevalent vertebral deformities predict mortality and hospitalization in older women with low bone mass. Fracture Intervention Trial Research Group. Journal of the American Geriatrics Society, 48, 241-249.
[25] van Schoor, N.M., Ewing, S.K., O’Neill, T.W., Lunt, M., Smit, J.H. and Lips, P. (2008) Impact of prevalent and incident vertebral fractures on utility: Results from a patient-based and a population-based sample. Quality of Life Research, 17, 159-167.
[26] Silverman, S.L., Minshall, M.E., Shen, W., Harper, K.D. and Xie, S. (2001) The relationship of health-related quality of life to prevalent and incident vertebral fractures in postmenopausal women with osteoporosis: Results from the multiple outcomes of raloxifene evaluation study. Arthritis and Rheumatism, 44, 2611-2619.
[27] Borgstrom, F., Zethraeus, N., Johnell, O., Lidgren, L., Ponzer, S., Svensson, O., Abdon, P., Ornstein, E., Lunsjö, K., Thorngren, K.G., Sernbo, I., Rehnberg, C. and Jönsson, B. (2006) Costs and quality of life associated with osteoporosis-related fractures in Sweden. Osteoporosis International, 17, 637-650.
[28] Schneider, D.L., von Muhlen, D., Barrett-Connor, E. and Sartoris, D.J. (2004) Kyphosis does not equal vertebral fractures: The Rancho Bernardo study. Journal of Rheumatology, 31, 747-752.
[29] Kado, D.M., Prenovost, K. and Crandall, C. (2007) Narrative review: Hyperkyphosis in older persons. Annals of Internal Medicine, 147, 330-338.
[30] Katzman, W.B., Huang, M.H., Lane, N.E., Ensrud, K.E. and Kado, D.M. (2013) Kyphosis and decline in physical function over 15 years in older community-dwelling women: The study of osteoporotic fractures. Journals of Gerontology: Series A, 68, 976-983.
[31] Katzman, W.B., Vittinghoff, E., Ensrud, K., Black, D.M. and Kado, D.M. (2011) Increasing kyphosis predicts worsening mobility in older community-dwelling women: A prospective cohort study. Journal of the American Geriatrics Society, 59, 96-100.
[32] Kado, D.M., Huang, M.H., Nguyen, C.B., Barrett-Connor, E. and Greendale, G.A. (2007) Hyperkyphotic posture and risk of injurious falls in older persons: The Rancho Bernardo study. Journals of Gerontology: Series A, 62, 652-657.
[33] Huang, M.H., Barrett-Connor, E., Greendale, G.A. and Kado, D.M. (2006) Hyperkyphotic posture and risk of future osteoporotic fractures: The Rancho Bernardo study. Journal of Bone and Mineral Research, 21, 419-423.
[34] Kado, D.M., Huang, M.H., Karlamangla, A.S., Barrett-Connor, E. and Greendale, G.A. (2004) Hyperkyphotic posture predicts mortality in older community-dwelling men and women: A prospective study. Journal of the American Geriatrics Society, 52, 1662-1667.
[35] Tanigawa, N., Kariya, S., Komemushi, A., Nakatani, M., Yagi, R. and Sawada, S. (2012) Added value of percutaneous vertebroplasty: Effects on respiratory function. AJR American Journal of Roentgenology, 198, W51-W54.