人血清中游离氨基酸指纹图谱的初步研究
A Preliminary Study on Free Amino Acid Fingerprint of Human Serum
摘要:
目的:建立人血清中游离氨基酸的指纹图谱。方法:采用L-8900全自动氨基酸分析仪测定健康人群血清中的游离氨基酸,选择15个主要特征峰为指纹图谱共有峰。结果:建立了12批人血清样品的游离氨基酸指纹图谱。结论:建立的指纹图谱有较好的精密度、重复性和稳定性,可作为人血清游离氨基酸指纹图谱库的理论基础。
Abstract:
Object: To establish free amino acid fingerprint of human serum. Method: The free amino acid of serum from the healthy persons was determined by the L-8900 automatic amino acid analyzer, and 15 major characteristic peaks of fingerprint were chosen as the common peak. Result: Free amino acid fingerprint of 12 batches of human serum was established. Conclusion: The fingerprint has preferably precision, repeatability and stability; it can be used as the theoretical basis of free amino acid fingerprint database of human serum.
参考文献
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周淑芬, 刘树业, 丁贤. 肝硬化与肝癌患者血浆氨基酸分析[J]. 临床肝胆病杂志, 2009, 25(3): 22.
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