探讨双脉冲多普勒技术测量Tei指数在成人健康体检中评估左室舒张功能的应用价值

Study on Evaluating the Value of Tei Index in the Evaluation of Left Ventricular Diastolic Function in Adult Health Examination by Double Pulse Doppler Technique

摘要: 目的：探讨双脉冲多普勒技术测量Tei指数在成人健康体检中评估左室舒张功能的应用价值。方法：选取体检中心健康成人113例，根据脉冲多普勒二尖瓣下血流E/A值及组织多普勒二尖瓣环运动速度e’/a’比值分为组1 (41例完全正常)、组2 (40例E/A、e’/a’ < 1)、组3 (42例E/A > 1而e’/a’ < 1)三组，采用双脉冲多普勒技术同步测量左心功能的Tei指数、舒张早期二尖瓣血流E峰与二尖瓣环运动速度e’比值(E/e’)等参数，采用统计软件SPSS 19.0对数据进行分析。结果：Tei指数在组2、组3中均较组1增高，三组之间均有差异(P < 0.05)，组2高于组1。Tei指数与等容舒张期IVRT、舒张早期二尖瓣血流E、组织多普勒二尖瓣环运动e’ (隔侧及侧壁)、E/A有相关性(P < 0.05)。舒张功能减低与高血压及糖尿病家族史、吸烟(1包/天)及酗酒、熬夜及睡眠差、工作压力大等精神因素、肥胖、缺乏运动有很强的相关性。结论：双脉冲多普勒可同步测量Tei指数等指标，提高了诊断左室舒张功能不全的准确性。

Abstract: Objective: To investigate the value of Tei index in the evaluation of left ventricular diastolic function in adult health examination by double pulse Doppler technique measurement. Methods: 113 healthy adults in the physical examination center were assigned, respectively. According to Doppler E/A of mitral valve blood flow pulse and tissue Doppler velocity of mitral annulus e '/a', they were divided into group 1 (41 cases were completely normal) and group 2 (40 cases of E/A, e '/a' < 1), group 3 (42 cases of E/A > 1, e'/a' < 1). Three groups were measured by double pulse Doppler synchronous of left ventricular function, Tei index and E peak early diastolic mitral flow velocity of mitral annulus E ratio (E/e) and other parameters, and SPSS 19 statistical software was used for data analysis. Results: The Tei index in group 3 and group 2 were significantly higher than that in group 1, and there were differences between the three groups (P < 0.05). The group 2 was higher than group 1. Tei index has correlation with isovolumic IVRT, early diastolic mitral flow E, mitral annulus tissue Doppler e' (septal and lateral wall side) and E/A (P < 0.05). Diastolic dysfunction has a strong correlation with hypertension and family history of diabetes, smoking (1 packs/day) and alcohol, staying up late and sleep poorly, work pressure and other mental factors, obesity, lacking of exercise. Conclusion: Double pulse Doppler can measure Tei index synchronously, and improve the accuracy of diagnosis of left ventricular diastolic dysfunction.