[1]
|
Nidheesh, D., Abhay, S., Neha, P., et al. (2015) Swertisin an Anti-Diabetic Compound Facilitate Islet Neogenesis from Pancreatic Stem/Progenitor Cells via p-38 MAP Kinase-SMAD Pathway:An In-Vitro and In-Vivo Study. PLoS ONE, 10, e0128244. https://doi.org/10.1371/journal.pone.0128244
|
[2]
|
Zhou, Q. and Melton, D.A. (2018) Pancreas Regeneration. Nature, 557, 351-358.
https://doi.org/10.1038/s41586-018-0088-0
|
[3]
|
Cano, D.A., Rulifson, I.C., Heiser, P.W., et al. (2008) Regulated Beta-Cell Regeneration in the Adult Mouse Pancreas. Diabetes, 57, 958-966. https://doi.org/10.2337/db07-0913
|
[4]
|
Dor, Y., Brown, J., Martinez, O.I. and Melton, D.A. (2004) Adult Pancreatic Beta-Cells Are Formed by Self-Duplication Rather than Stem-Cell Differentiation. Nature, 429, 41-46. https://doi.org/10.1038/nature02520
|
[5]
|
Walpita, D., Hasaka, T., Spoonamore, J., et al. (2011) A Human Islet Cell Culture System for High-Throughput Screening. Journal of Biomolecular Screening, 17, 509. https://doi.org/10.1177/1087057111430253
|
[6]
|
Wang, P., Alvarez-Perez, J.C., Felsenfeld, D.P., et al. (2015) A High-Throughput Chemical Screen Reveals that Harmine-Mediated Inhibition of DYRK1A Increases Human Pancre-atic Beta Cell Replication. Nature Medicine, 21, 383-388. https://doi.org/10.1038/nm.3820
|
[7]
|
Dirice, E., Wal-pita, D., Vetere, A., et al. (2016) Inhibition of DYRK1A Stimulates Human Beta-Cell Proliferation. Diabetes, 65, 1660-1671. https://doi.org/10.2337/db15-1127
|
[8]
|
Kondegowda, N., Fenutria, R., Pollack, I., et al. (2015) Os-teoprotegerin and Denosumab Stimulate Human Beta Cell Proliferation through Inhibition of the Receptor Activator of NF-κB Ligand Pathway. Cell Metabolism, 22, 77-85.
https://doi.org/10.1016/j.cmet.2015.05.021
|
[9]
|
Hang, Y. and Stein, R. (2011) MafA and MafB Activity in Pan-creatic β Cells. Trends in Endocrinology & Metabolism, 22, 364-373. https://doi.org/10.1016/j.tem.2011.05.003
|
[10]
|
Romer, A.I. and Sussel, L. (2015) Pancreatic Islet Cell Develop-ment and Regeneration. Current Opinion in Endocrinology & Diabetes and Obesity, 22, 255-264. https://doi.org/10.1097/MED.0000000000000174
|
[11]
|
Afelik, S., Chen, Y.L. and Pieler, T. (2006) Combined Ectopic Expression of Pdx1 and Ptf1a/p48 Results in the Stable Conversion of Posterior Endoderm into Endocrine and Exocrine Pancreatic Tissue. Genes & Development, 20, 1441-1446.
https://doi.org/10.1101/gad.378706
|
[12]
|
Oropez, D. and Horb, M. (2012) Transient Expression of Ngn3 in Xenopusendoderm Promotes Early and Ectopic Development of Pancreatic Beta and Delta Cells. Genesis, 50, 271-285. https://doi.org/10.1002/dvg.20828
|
[13]
|
Gradwohl, G., Dierich, A., Lemeur, M., et al. (2000) Neurogenin3 Is Required for the Development of the Four Endocrine Cell Lineages of the Pancreas. Proceedings of the National Academy of Sciences, 97, 1607-1611.
https://doi.org/10.1073/pnas.97.4.1607
|
[14]
|
Jeon J., Correa-Medina, M., Ricordi, C., Edlund, H. and Diez, J.A. (2009) Endocrine Cell Clustering during Human Pancreas Development. Journal of Histochemistry and Cytochemistry, 57, 811-824.
https://doi.org/10.1369/jhc.2009.953307
|
[15]
|
Napolitano, T., Avolio, F., Courtney, M., et al. (2015) Pax4 Acts as a Key Player in Pancreas Development and Plasticity. Seminars in Cell & Developmental Biology, 44, 107-114. https://doi.org/10.1016/j.semcdb.2015.08.013
|
[16]
|
Ben-Othman, N., Vieira, A., Courtney, M., et al. (2017) Long-Term GABA Administration Induces Alpha Cell-Mediated Beta-like Cell Neogenesis. Cell, 168, 73-85. https://doi.org/10.1016/j.cell.2016.11.002
|
[17]
|
Weir, G.C. and Bonner-Weir, S. (2017) GABA Signaling Stimu-lates β Cell Regeneration in Diabetic Mice. Cell, 168, 7-9. https://doi.org/10.1016/j.cell.2016.12.006
|
[18]
|
Li, J., Casteels, T., Frogne, T., et al. (2017) Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity. Cell, 168, 86-100.e15. https://doi.org/10.1016/j.cell.2016.11.010
|
[19]
|
Talitha, V.D.M., Lee, S., Noordeloos, E., et al. (2017) Artemether Does Not Turn α Cells into β Cells. Cell Metabolism, 27, 218-225.e4. https://doi.org/10.1016/j.cmet.2017.10.002
|
[20]
|
Cheng, C.W., Villani, V., Buono, R., et al. (2017) Fast-ing-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes. Cell, 168, 775-788.e12. https://doi.org/10.1016/j.cell.2017.01.040
|