血液学指标在晚期肺腺癌患者预后中的意义

The Significance of Hematologic Indicators in the Prognosis of Patients with Advanced Lung Adenocarcinoma

摘要: 目的：本研究目的是探索血液学指标在晚期肺腺癌患者预后中的意义，为临床预测患者预后提供依据。方法：收集初次就诊于我院的晚期肺腺癌患者，并收集患者基本信息。用Kaplan Meier法绘制生存曲线，用COX比例风险回归进行单因素及多因素分析。结果：共收集225名晚期肺腺癌患者，通过分析得出纤维蛋白原、LDH与患者的PFS相关，同时也是患者PFS的独立预后因素。纤维蛋白原、NLR与患者的OS相关。结论：纤维蛋白原、LDH是晚期肺腺癌患者PFS的独立因素。

Abstract: Objective: The purpose of this study was to explore the significance of hematologic indicators in the prognosis of patients with advanced lung adenocarcinoma and to provide a basis for clinical prediction of the prognosis of patients. Methods: Patients with advanced lung adenocarcinoma who visited our hospital for the first time were collected, and their basic information was also collected. The survival curve was drawn by Kaplan Meier method, and univariate and multivariate analyses were performed by COX proportional risk regression. Results: A total of 225 patients with advanced lung adenocarcinoma were collected. Through analysis, it was concluded that fibrinogen and LDH were correlated with patients’ PFS and independent prognostic factors of patients’ PFS. Fibrinogen is associated with the patient’s OS. Conclusion: Fibrinogen and LDH are independent factors of PFS in patients with advanced lung adenocarcinoma.