神经干细胞与脑缺血损伤
Neural Stem Cells and Cerebral Ischemia Injury
摘要:
目的：探讨神经干细胞的定义、移植分化及调控因素，以及与脑缺血之间的关系。方法：通过阐述神经干细胞的定义及生物学特性，结合神经干细胞移植及微环境调控，进一步将神经干细胞与脑缺血损伤修复机制加以联系。结果：神经干细胞能够修复脑缺血损伤，但要克服定向分化、炎症及排斥反应等问题。结论：神经干细胞移植可用于脑缺血损伤神经修复。
Objective: To explore the definition, transplantation, differentiation, regulator factors and the relation of neural stem cells (NSCs) and cerebral ischemia injury. Methods: To expound the definition and biological characteristics of NSCs, unite NSCs transplantation, micro environment control and to contact NSCs and cerebral ischemia injury mechanism. Results: Neural stem cells may repair cerebral ischemia injury, but overcome the problem of directional differentiation, inflammation and reject reaction. Conclusion: The transplantation of neural stem cells can be used in the neural restoration of the cerebral ischemia injury.
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