均相沉积法制备磁性羟基磷灰石
Fabrication of Magnetic Hydroxyapatite by a Homogeneous Precipitation Method
DOI: 10.12677/MS.2016.64028, PDF, HTML, XML, 下载: 2,397  浏览: 4,681  国家科技经费支持
作者: 闫 艳, 张 熠, 左 奕, 李玉宝, 李吉东：四川大学分析测试中心，纳米生物材料研究中心，四川 成都
关键词: 羟基磷灰石；四氧化三铁；磁性；柠檬酸铵；Hydroxyapatite； Ferroferric Oxide； Magnetism； Ammonium Citrate
摘要: 本文将Fe3O4纳米颗粒分散在Ca、P溶液中，通过尿素酶催化水解尿素提高Ca、P溶液PH值，以纳米Fe3O4为成核位点，通过均相沉积法制备具有核–壳结构的Fe3O4/HA磁性复合物。通过X射线衍射(XRD)、透射电镜(TEM)、扫描电镜(SEM)等分析手段分析探讨了Ca/P摩尔比和分散剂柠檬酸铵用量对磁性羟基磷灰石复合颗粒组成、结构和颗粒尺寸的影响。结果表明当溶液中Ca/P摩尔比为5:3，分散剂柠檬酸铵用量为1.5~3.0 g/500ml，Fe3O4磁性粒子基本完全被沉积的羟基磷灰石包覆，可制得颗粒尺寸较小的球状核壳结构磁性Fe3O4/HA复合物。
Abstract: A core-shell nano-iron oxide/hydroxyapatite (Fe3O4/HA) composite was synthesized by using a homogeneous precipitation method. Fe3O4 nano-particles synthesized by chemical precipitation were dispersed and used as substrate in Ca, P solution to deposit HA on the Fe3O4 spheres through slowly increase of pH by decomposition of urea using urease as the catalytic. The influence of Ca/P molar ratio and varying dosages of dispersing agent (ammonium citrate) on the composition, structure and particle diameter of fabricated Fe3O4/HA was investigated. The obtained samples were characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM) and scan-ning electron microscopy (SEM). The results showed that a spherical core-shell Fe3O4/HA composite with magnetic properties, and smaller particle size were obtained under Ca/P molar ratio of 5:3 and ammonium citrate concentration of 1.5 - 3.0 g/500ml.
文章引用：闫艳, 张熠, 左奕, 李玉宝, 李吉东. 均相沉积法制备磁性羟基磷灰石[J]. 材料科学, 2016, 6(4): 223-229. http://dx.doi.org/10.12677/MS.2016.64028

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