红霉素表面分子印迹聚合物的制备及其吸附性能研究
Preparation of Surface Molecularly Imprinted Polymers for Erythromycin and Its Adsorption Properties
DOI: 10.12677/AAC.2017.72009, PDF, HTML, XML, 下载: 2,128  浏览: 5,029  科研立项经费支持
作者: 程迪迪, 刘彩红：泰山医学院，药学院，山东 泰安
关键词: 表面分子印迹聚合物；红霉素；分子识别；吸附性能；Surface Molecularly Imprinted Polymer； Erythromycin (EM)； Molecular Recognition； Adsorption Properties
摘要: 采用表面分子印迹技术，以红霉素(EM)为模板分子，制备红霉素分子印迹聚合物(EM-MIPs)。利用扫描电镜和粒径分析对聚合物进行表征，通过静态吸附平衡实验、 动态吸附实验及选择性实验考察聚合物的吸附性能，结果显示聚合物成功接枝在硅胶表面，EM-MIPs对红霉素具有良好的吸附性能和特异选择识别能力。
Abstract: This study aims to prepare erythromycin imprinted polymers(EM-MIPs) by surface polymerization method at the surface of modified silica particles by using erythromycin(EM) as the template molecule. The synthesized EM-MIPs were characterized by scanning electron microscope (SEM) and particle size analysis. The results indicated that the MIPs layer has been successfully grafted on the surface of silica particles. The adsorption and recognition properties the obtained polymers were evaluated by static binding test, dynamic binding test and selective binding test. The results showed that EM-MIPs displayed higher recognition ability and adsorption capacity to the template molecule- EM.
文章引用：程迪迪, 刘彩红. 红霉素表面分子印迹聚合物的制备及其吸附性能研究[J]. 分析化学进展, 2017, 7(2): 67-73. https://doi.org/10.12677/AAC.2017.72009

参考文献

[1] 张晓燕, 郑定钊, 袁芳, 等. 高效液相色谱-串联质谱法测定蜂蜜中的红霉素及其代谢物[J]. 分析测试学报, 2013, 32(9): 1131-1134.
[2] 严丽娟, 张峰, 方恩华, 等. 超高效液相色谱-电喷雾串联质谱法测定动物饲料中的大环内酯类和林可胺类抗生素[J], 色谱, 2010, 28(11): 1038-1042.
[3] 龙泽荣, 徐微微, 鹿毅, 等. 分子印迹固相萃取-超高效液相色谱法测定河水中的碱性橙 II[J]. 理化检验-化学分册, 2014, 50(8): 937-743.
[4] Zeng, H., Wang, Y.Z., Liu, X.J., et al. (2012) Preparation of Molecular Imprinted Polymers Using Bi- Functional Monomer and Bi- Crosslinker for Solid- Phase Extraction of Rutin. Talanta, 93, 172-181. https://doi.org/10.1016/j.talanta.2012.02.008
[5] 汤凯洁, 罗秋水, 余瑞龙, 等. 分子印迹固相萃取/高效液相色谱法测定猪肝中盐酸克伦特罗的方法研究[J]. 分析测试学报, 2016, 35(1): 115-118.
[6] Saman, A.D., Alireza, H.N., Ebadullah, N., et al. (2014) Magnetic Molecularly Imprinted Polymer Nanoparticles for the Solid-Phase Extraction of Paracetamol from Plasma Samples, Followed Its Determination by HPLC. Microchimica Acta, 181, 1823-1832. https://doi.org/10.1007/s00604-014-1230-9
[7] 郑鹏磊, 罗智敏, 畅瑞苗, 等. 青霉噻唑酸表面分子印迹聚合物的制备及其吸附性能的考察[J]. 色谱, 2015, 33(9): 957-965.
[8] 尹晓斐, 汤水粉, 刘玮, 等. 表面分子印迹技术研究进展[J]. 福州大学学报(自然科学版), 2011, (5): 639-648.
[9] Haupt, K., Linares, A.V., Bompart, M., et al. (2012) Molecularly Imprinted Polymers. Topics in Current Chemistry, 325, 1-28. https://doi.org/10.1007/128_2011_307
[10] Schwarz, L.J., Danylec, B. and Yang, Y.Z. (2011) Enrichment of (E)-Resveratrol from Peanut by Product with Molecularly Imprinted Polymers. Journal of Agricultural and Food Chemistry, 59, 3539-3543. https://doi.org/10.1021/jf104230f
[11] Yanmamura, H.I. and Kuhar, M.J. (1985) Neurotransmitter Receptor Binding. Raven Press, New York, 485-489.

为你推荐