脑损伤后植物状态患者功能核磁共振脑区连接强度变化及其意义

Changes and Significance of Brain Magnetic Resonance Area Connectivity in Patients with Vegetative State after Brain Injury

摘要: 目的：研究脑损伤后植物状态患者功能核磁共振脑区连接强度变化情况，为进一步探究影响患者觉醒与意识水平的脑区提供参考。方法：选取三位脑损伤后植物状态患者的脑fMRI图像，并与三位正常同龄人作对比，显示患者脑部各功能区之间连接强度发生的变化，并利用统计参数图谱对数据进行分析。结果：通过分析图像，可以得出脑室出血所致意识障碍患者额叶间、额叶与基底神经节间的连接强度弱于相同年龄的健康人群。结论：本研究病例提示，脑室出血所致意识障碍患者额叶间、额叶与基底神经节间的连接强度减弱，在原发病治疗的基础上，加强额叶与基底神经节相关功能的锻炼，对脑出血患者的康复治疗具有指导意义。

Abstract: Objective: To study the changes of brain magnetic resonance brain intensity in patients with plant status after brain injury, so as to provide reference for further exploring the brain areas that affect the arousal and consciousness of the patients. Methods: The brain fMRI images of patients with plant status after three brain lesions were selected, and compared with three normal peers, showing changes in the intensity of the connection between the functional regions of the patient’s brain, and the statistical parameters were used to analyze the data. Results: By analyzing the image, can be obtained from the intensity of frontal lobe, frontal lobe and basal ganglia junction of conscious patients with intraventricular hemorrhage is weaker than that of other healthy peers. Conclusion: This case prompted that patient with unconsciousness caused by intraventricular hemorrhage frontal lobe, frontal lobe and basal ganglia junction strength weakened. On the basis of primary disease treatment, strengthens the frontal lobe and the basal ganglia related function exercise, it has guiding significance for rehabilitation treatment of patients with cerebral hemorrhage.