蝶骨孤立性浆细胞瘤一例并文献复习

Solitary Plasmacytoma of the Sphenoid Bone: A Case Report and Literature Review

摘要: 目的：探讨颅内孤立性骨浆细胞瘤的临床特征，诊断和治疗方案选择。方法：回顾性分析1例蝶骨孤立性浆细胞瘤患者的临床资料，并复习相关文献。结果：本例患者因“右侧眼球突出”入院，颅脑磁共振显示右侧蝶颞区见一均匀强化肿块，大小约5.7 × 4.1 × 7.0 cm。术后病理结果为浆细胞瘤。为排除多发性骨髓瘤，对患者进行相关检查，并最终诊断为蝶骨孤立性浆细胞瘤。患者术后恢复良好，并于出院后2周接受放射治疗。截至末次随访，未见肿瘤复发或进展。结论：颅内孤立性骨浆细胞瘤临床少见，确诊依赖病理组织学检查和骨髓检验，主要治疗方式为放射治疗。

Abstract: Objective: This study aims to explore the clinical characteristics, diagnostic approach, and treatment strategies for intracranial solitary bone plasmacytoma. Method: A retrospective analysis of clinical data from one case of solitary plasmacytoma of the sphenoid bone was conducted, along with a review of relevant literature. Result: The patient was admitted to the hospital with a progressive proptosis of the right eyeball. Brain magnetic resonance imaging revealed a homogeneous enhancing mass in the right sphenotemporal region, measuring approximately 5.7 × 4.1 × 7.0 cm. Postoperative pathology confirmed the diagnosis of plasmacytoma. To rule out multiple myeloma, the patient underwent comprehensive examinations, ultimately leading to the diagnosis of solitary plasmacytoma of the sphenoid bone. The patient recovered well postoperatively and received radiotherapy two weeks after discharge. At the latest follow-up, no tumor recurrence or progression was observed. Conclusion: Intracranial solitary bone plasmacytoma is a rare entity, histopathological examination and bone marrow analysis are the key to the diagnosis of this disease. The optimal choice of treatment is radiotherapy.