路易斯酸对苯乙酮和四丁基三溴化铵反应的影响

Effects of Lewis Acids on the Reaction of Acetophenone and Tetrabutylammonium Tribromide

摘要: 本文考察了苯乙酮和四丁基三溴化铵(TBABr₃)的溴代反应中路易斯酸对反应速率的影响。在所研究的路易斯酸的范围内，ZnCl₂、AlCl₃和FeCl₃能加速反应的进行，但是FeCl₂和NiCl₂抑制了溴代反应。从结果来看，FeCl₃不仅能显著缩短反应时间，同时收率也有所提高。

Abstract: We investigate the effects of some Lewis acids (ZnCl₂, AlCl₃, FeCl₃, FeCl₂, and NiCl₂) on the α-bro- mination rate of acetophenone with tetrabutylammonium tribromide. It is found that some Lewis acids, such as ZnCl₂, AlCl₃, and FeCl₃, can accelerate bromination of acetophenone, but others such as FeCl₂ and NiCl₂ inhibited the bromination. Among the catalytic Lewis acids, FeCl₃ could significantly accelerate the reaction without loss of the yield.