中医穴位疗法对化疗性便秘有效性的Meta分析

The Efficacy of Acupoint Therapy of Traditional Chinese Medicine for the Treatment of Constipation: A Meta Analysis

摘要: 目的：系统评价穴位疗法对化疗性便秘的防治效果。方法：以中文和英文两种语言检索Cochrane图书馆、PubMed、中国期刊全文数据库(CNKI)、中国科技期刊全文数据库(VIP)、万方数据库(均从建库至2016年4月)等数据库。收集所有使用穴位疗法(穴位针刺、穴位按摩、经皮穴位电刺激、穴位按压、穴位埋线、穴位贴敷)防治化疗性便秘的随机对照实验、半随机对照实验。由2名研究者按照纳入和排除标准筛选并提取资料，参考Cochrane系统评价手册质量评价标准进行质量评价，使用Review Manager 5.2软件进行Meta分析。结果：共纳入1项随机对照实验、9项半随机对照实验，共952例患者。Meta分析结果显示，穴位疗法防治化疗性便秘的有效性较常规护理好，合并效应有统计学意义[RR = (1.15~2.28)], CI = [(1.15 − 2.28)~(1.51 − 3.24)], [P = (0.00001~0.02]。结论：中医穴位疗法对化疗性便秘的有效性较好，护理人员在实施化疗性便秘护理时应考虑在专业范围内引入中医穴位疗法辩证施护。

Abstract: Objective: To evaluate the effect of acupoint therapy on the prevention and treatment of chemo-therapy induced constipation. Methods: The relevant randomized controlled trials, quasi-randomized controlled trails (acupuncture, acupoint massage, transcutaneous electrical acupoint stimulation, acupressure, catgut implantation at acupoint, acupoint sticking) were searched in the Cochrane Library, PubMed, Chinese journal full text database (CNKI), China Science and technology journals full text database (VIP), Wanfang database (from inception to 2016 April). According to the inclusion and exclusion criteria, 2 researchers selected and extracted the studies, and the quality of included studies was evaluated according to Cochrane Handbook for systematic reviews of interventions. Meta analysis was conducted by using RevMan 5.2. Results: One randomized controlled trials, nine quasi-randomized controlled trials involving 952 patients were included. Meta analysis showed that the efficacy of acupoint therapy for chemotherapy induced constipation was better than that of conventional nursing, and the combined effect was statistically significant: RR = (1.15 - 2.28), CI = [(1.15 − 2.28) - (1.51 − 3.24)], P = (0.00001 - 0.02). Conclusion: Traditional Chinese treatment acupoint therapy is effective in the treatment of chemotherapy induced constipation. And nursing staff should consider the application of acupoint therapy in curing chemotherapy induced constipation.