炎症因子与肿瘤关系及其机制研究进展

Research Progress on the Relationship between Inflammatory Factors and Tumor and Its Mechanism

摘要: 炎症与肿瘤之间的关系密不可分，越来越多的证据表明炎症是肿瘤进展的关键组成部分，癌症多是由于感染部位慢性刺激和炎症而产生的。值得注意的是，炎症细胞在肿瘤微环境中起到了重要协调作用，是肿瘤过程中不可或缺的参与者，在促进肿瘤增殖、生存以及迁移等方面扮演了重要角色。此外，肿瘤的易感性和严重程度可能与炎症因子基因的功能多态性有关，炎症因子或许在肿瘤的免疫方面起着重要作用，因此探讨炎症指标与肿瘤之间的联系对深入了解肿瘤有着重大意义。

Abstract: The relationship between inflammation and tumors is inextricably linked, and there is growing evidence that inflammation is a key component of tumor progression. Cancer is often caused by chronic irritation and inflammation at the site of infection. It is noteworthy that inflammatory cells play an important coordinating role in the tumor microenvironment and are indispensable participants in the tumor process, playing an important role in promoting tumor proliferation, survival and migration. In addition, the susceptibility and severity of tumors may be related to the functional polymorphism of inflammatory factor genes, which may play an important role in tumor immunity. Therefore, it is of great significance to explore the relationship between inflammatory indicators and tumors for further understanding of tumors.