[1]
|
Andrews, N.C. and Schmidt, P.J. (2007) Iron Homeostasis. Annual Review of Physiology, 69, 69-85.
https://doi.org/10.1146/annurev.physiol.69.031905.164337
|
[2]
|
Brissot, P., Ropert, M., Le Lan, C., et al. (2012) Non-Transferrin Bound Iron: A Key Role in Iron Overload and Iron Toxicity. Biochimica et Biophysica Acta (BBA)-General Subjects, 1820, 403-410.
https://doi.org/10.1016/j.bbagen.2011.07.014
|
[3]
|
Milto, I.V., Suhodolo, I.V., Prokopieva, V.D., et al. (2016) Molecular and Cellular Bases of Iron Metabolism in Humans. Biochemistry (Moscow), 81, 549-564. https://doi.org/10.1134/S0006297916060018
|
[4]
|
Babitt, J.L., Huang, F.W., Wrighting, D.M., et al. (2006) Bone Morphogenetic Protein Signaling by Hemojuvelin Regulates Hepcidin Expression. Nature Genetics, 38, 531-539. https://doi.org/10.1038/ng1777
|
[5]
|
Chaston, T.B., Matak, P., Pourvali, K., et al. (2011) Hypoxia Inhibits Hepcidin Expression in HuH7 Hepatoma Cells via Decreased SMAD4 Signaling. American Journal of Physiology-Cell Physiology, 300, C888-C895.
https://doi.org/10.1152/ajpcell.00121.2010
|
[6]
|
Novo, E., Cannito, S., Paternostro, C., et al. (2014) Cellular and Molecular Mechanisms in Liver Fibrogenesis. Archives of Biochemistry and Biophysics, 548, 20-37. https://doi.org/10.1016/j.abb.2014.02.015
|
[7]
|
Lozano, R., Naghavi, M., Foreman, K., et al. (2012) Global and Regional Mortality from 235 Causes of Death for 20 Age Groups in 1990 and 2010: A Systematic Analysis for the Global Burden of Disease Study 2010. The Lancet, 380, 2095-2128. https://doi.org/10.1016/S0140-6736(12)61728-0
|
[8]
|
Ioav, C.Z. (2014) Labile Iron in Cells and Body Fluids: Physiology, Pathology, and Pharmacology. Frontiers in Pharmacology, 5, Article No. 45. https://doi.org/10.3389/fphar.2014.00045
|
[9]
|
Fargion, S., Mattioli, M., Fracanzani, A.L., et al. (2001) Hyperferritinemia, Iron Overload, and Multiple Metabolic Alterations Identify Patients at Risk for Nonalcoholic Steatohepatitis. The American Journal of Gastroenterology, 96, 2448-2455. https://doi.org/10.1111/j.1572-0241.2001.04052.x
|
[10]
|
Heymann, F., Trautwein, C. and Tacke, F. (2009) Monocytes and Macrophages as Cellular Targets in Liver Fibrosis. Inflammation & Allergy-Drug Targets, 8, 307-318. https://doi.org/10.2174/187152809789352230
|
[11]
|
Duval, F., Moreno-Cuevas, J.E., González-Garza, M.T., et al. (2014) Liver Fibrosis and Protection Mechanisms Action of Medicinal Plants Targeting Apoptosis of Hepatocytes and Hepatic Stellate Cells. Advances in Pharmacological Sciences, 2014, Article ID: 373295. https://doi.org/10.1155/2014/373295
|
[12]
|
Zhang, M., Wang, F.L., Zhu, J.Y., et al. (2013) Liver Myofibroblasts Regulate the Phenotype and Function of Monocytes through Soluble Factors in Cirrhosis. Experimental and Therapeutic Medicine, 5, 143-149.
https://doi.org/10.3892/etm.2012.767
|
[13]
|
Sebastiani, G., Tempesta, D. and Alberti, A. (2012) Hepatic Iron Overload Is Common in Chronic Hepatitis B and Is More Severe in Patients Coinfected with Hepatitis D Virus. Journal of Viral Hepatitis, 19, e170-e176.
https://doi.org/10.1111/j.1365-2893.2011.01508.x
|
[14]
|
Philippe, M.A., Ruddell, R.G. and Ramm, G.A. (2007) Role of Iron in Hepatic Fibrosis: One Piece in the Puzzle. World Journal of Gastroenterology: WJG, 13, 4746. https://doi.org/10.3748/wjg.v13.i35.4746
|
[15]
|
Arezzini, B., Lunghi, B., Lungarella, G., et al. (2003) Iron Overload Enhances the Development of Experimental Liver Cirrhosis in Mice. The International Journal of Biochemistry & Cell Biology, 35, 486-495.
https://doi.org/10.1016/S1357-2725(02)00298-4
|
[16]
|
Ramm, G.A., Crawford, D., Powell, L.W., et al. (1997) Hepatic Stellate Cell Activation in Genetic Haemochromatosis. Lobular Distribution, Effect of Increasing Hepatic Iron and Response to Phlebotomy. Journal of Hepatology, 26, 584-592. https://doi.org/10.1016/S0168-8278(97)80424-2
|
[17]
|
Gardi, C., Arezzini, B., Fortino, V., et al. (2002) Effect of Free Iron on Collagen Synthesis, Cell Proliferation and MMP-2 Expression in Rat Hepatic Stellate Cells. Biochemical Pharmacology, 64, 1139-1145.
https://doi.org/10.1016/S0006-2952(02)01257-1
|
[18]
|
Lurie, Y., Webb, M., Cytter-Kuint, R., et al. (2015) Non-Invasive Diagnosis of Liver Fibrosis and Cirrhosis. World Journal of Gastroenterology, 21, 11567-11583. https://doi.org/10.3748/wjg.v21.i41.11567
|
[19]
|
Castiella, A., Zapata, E. and Alústiza, J.M. (2010) Non-Invasive Methods for Liver Fibrosis Prediction in Hemochromatosis: One Step Beyond. World Journal of Hepatology, 2, 251. https://doi.org/10.4254/wjh.v2.i7.251
|
[20]
|
Cohen, L.A., Gutierrez, L., Weiss, A., et al. (2010) Serum Ferritin Is Derived Primarily from Macrophages through a Nonclassical Secretory Pathway. Blood: The Journal of the American Society of Hematology, 116, 1574-1584.
https://doi.org/10.1182/blood-2009-11-253815
|
[21]
|
Trinder, D., Ayonrinde, O.T. and Olynyk, J.K. (2008) HCV, Iron, and Oxidative Stress: The New Choreography of Hepcidin. Gastroenterology, 134, 348-351. https://doi.org/10.1053/j.gastro.2007.11.048
|
[22]
|
Koperdanova, M. and Cullis, J.O. (2015) Interpreting Raised serum Ferritin Levels. BMJ, 351, h3692.
https://doi.org/10.1136/bmj.h3692
|
[23]
|
Cakir, M., Erduran, E., Turkmen, E.S., et al. (2015) Hepcidin Levels in Children with Chronic Liver Disease. Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association, 21, 300.
https://doi.org/10.4103/1319-3767.166205
|
[24]
|
Viveiros, A., Finkenstedt, A., Schaefer, B., et al. (2018) Transferrin as a Predictor of Survival in Cirrhosis. Liver Transplantation, 24, 343-351. https://doi.org/10.1002/lt.24981
|
[25]
|
Mao, W.L., Hu, Y., Lou, Y.F., et al. (2015) Abnormal Serum Iron Markers in Chronic Hepatitis B Virus Infection May Be Because of Liver Injury. European Journal of Gastroenterology & Hepatology, 27, 130.
https://doi.org/10.1097/MEG.0000000000000247
|
[26]
|
Hengeveld, P., Zuyderhoudt, F.M., Jöbsis, A.C., et al. (1982) Some Aspects of Iron Metabolism during Acute Viral Hepatitis. Hepato-Gastroenterology, 29, 138-141.
|
[27]
|
Rigamonti, C., Andorno, S., Maduli, E., et al. (2002) Iron, Hepatic Stellate Cells and Fibrosis in Chronic Hepatitis C. European Journal of Clinical Investigation, 32, 28-35. https://doi.org/10.1046/j.1365-2362.2002.0320s1028.x
|
[28]
|
Park, S.O., Kumar, M. and Gupta, S. (2012) TGF-β and Iron Differently Alter HBV Replication in Human Hepatocytes through TGF-β/BMP Signaling and Cellular microRNA Expression. PLoS ONE, 7, e39276.
https://doi.org/10.1371/journal.pone.0039276
|
[29]
|
Sikorska, K. (2016) The Iron Homeostasis Network and Hepatitis C Virus—A New Challenge in the Era of Directly Acting Antivirals. Virulence, 7, 620-622. https://doi.org/10.1080/21505594.2016.1191739
|
[30]
|
Kowdley, K.V., Belt, P., Wilson, L.A., et al. (2012) Serum Ferritin Is an Independent Predictor of Histologic Severity and Advanced Fibrosis in Patients with Nonalcoholic Fatty Liver Disease. Hepatology, 55, 77-85.
https://doi.org/10.1002/hep.24706
|
[31]
|
Romilda, C., Marika, P., Alessandro, S., et al. (2012) Oxidative DNA Damage Correlates with Cell Immortalization and Mir-92 Expression in Hepatocellular Carcinoma. BMC Cancer, 12, Article No. 177.
https://doi.org/10.1186/1471-2407-12-177
|
[32]
|
Tseng, H.H., Chang, J.G., Hwang, Y.H., et al. (2009) Expression of Hepcidin and Other Iron-Regulatory Genes in Human Hepatocellular Carcinoma and Its Clinical Implications. Journal of Cancer Research and Clinical Oncology, 135, 1413-1420. https://doi.org/10.1007/s00432-009-0585-5
|