[1]
|
Siegel, R.L., Miller, K.D., Goding Sauer, A., et al. (2020) Colorectal Cancer Statistics, 2020. CA: A Cancer Journal for Clinicians, 70, 145-164. https://doi.org/10.3322/caac.21601
|
[2]
|
Wang, Q., Xu, M., Sun, Y., et al. (2019) Gene Expression Profiling for Diagnosis of Triple-Negative Breast Cancer: A Multicenter, Retrospective Cohort Study. Fron-tiers in Oncology, 9, Article 354.
https://doi.org/10.3389/fonc.2019.00354
|
[3]
|
Lotfinejad, P., Jafarabadi, M.A., Shadbad, M.A., et al. (2020) Prog-nostic Role and Clinical Significance of Tumor-Infiltrating Lymphocyte (TIL) and Programmed Death Ligand 1 (PD-L1) Expression in Triple-Negative Breast Cancer (TNBC): A Systematic Review and Meta-Analysis Study. Diagnostics, 10, Article 704.
https://doi.org/10.3390/diagnostics10090704
|
[4]
|
Garrido-Castro, A.C., Lin, N.U. and Polyak, K. (2019) Insights into Molecular Classifications of Triple-Negative Breast Cancer: Improving Patient Selection for Treatment. Cancer Dis-covery, 9, 176-198.
https://doi.org/10.1158/2159-8290.CD-18-1177
|
[5]
|
Rey-Vargas, L., Sanabria-Salas, M.C., Fejerman, L. and Ser-rano-Gómez, S.J. (2019) Risk Factors for Triple-Negative Breast Cancer among Latina Women. Cancer Epidemiology, Biomarkers & Prevention, 28, 1771-1783.
https://doi.org/10.1158/1055-9965.EPI-19-0035
|
[6]
|
Burstein, M.D., Tsimelzon, A., Poage, G.M., et al. (2015) Comprehensive Genomic Analysis Identifies Novel Subtypes and Targets of Triple-Negative Breast Cancer. Clinical Cancer Research, 21, 1688-1698.
https://doi.org/10.1158/1078-0432.CCR-14-0432
|
[7]
|
Jiang, Y.-Z., Ma, D., Suo, C., et al. (2019) Genomic and Transcriptomic Landscape of Triple-Negative Breast Cancers: Subtypes and Treatment Strategies. Cancer Cell, 35, 428-440. https://doi.org/10.1016/j.ccell.2019.02.001
|
[8]
|
刘娟, 郑唯强. AR和SKP2在三阴性乳腺癌中的表达及临床意义[J]. 医学研究杂志, 2019, 48(8): 20-26, 4.
|
[9]
|
Liu, Y.-X., Zhang, K.-J. and Tang, L.-L. (2018) Clinical Significance of Androgen Receptor Expression in Triple Negative Breast Cancer—An Immunohistochemistry Study. Oncology Letters, 15, 10008-10016.
https://doi.org/10.3892/ol.2018.8548
|
[10]
|
Lehmann, B.D., Bauer, J.A., Schafer, J.M., et al. (2014) PIK3CA Muta-tions in Androgen Receptor-Positive Triple Negative Breast Cancer Confer Sensitivity to the Combination of PI3K and Androgen Receptor Inhibitors. Breast Cancer Research, 16, Article No. 406. https://doi.org/10.1186/s13058-014-0406-x
|
[11]
|
Rodríguez-Bautista, R., Caro-Sánchez, C.H., Cabrera-Galeana, P., et al. (2021) Immune Milieu and Genomic Alterations Set the Triple-Negative Breast Cancer Immunomodulatory Subtype Tumor Behavior. Cancers, 13, Article No. 6256. https://doi.org/10.3390/cancers13246256
|
[12]
|
Tsang, J.Y.S. and Tse, G.M. (2020) Molecular Classification of Breast Cancer. Advances in Anatomic Pathology, 27, 27-35. https://doi.org/10.1097/PAP.0000000000000232
|
[13]
|
Liedtke, C., Mazouni, C., Hess, K.R., et al. (2008) Response to Neoadjuvant Therapy and Long-Term Survival in Patients with Triple-Negative Breast Cancer. Journal of Clinical Oncology, 26, 1275-1281.
https://doi.org/10.1200/JCO.2007.14.4147
|
[14]
|
Sharma, P. (2016) From the Guest Editor: Immune Checkpoint Therapy as a Weapon against Cancer. The Cancer Journal, 22, 67. https://doi.org/10.1097/PPO.0000000000000184
|
[15]
|
Lu, P., Weaver, V.M. and Werb, Z. (2012) The Extracellular Matrix: A Dynamic Niche in Cancer Progression. Journal of Cell Biology, 196, 395-406. https://doi.org/10.1083/jcb.201102147
|
[16]
|
Orimo, A., Gupta, P.B., Sgroi, D.C., et al. (2005) Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion. Cell, 121, 335-348.
https://doi.org/10.1016/j.cell.2005.02.034
|
[17]
|
Ge, Z. and Ding, S. (2020) The Crosstalk Between Tu-mor-Associated Macrophages (TAMs) and Tumor Cells and the Corresponding Targeted Therapy. Frontiers in Oncolo-gy, 10, Article 590941.
https://doi.org/10.3389/fonc.2020.590941
|
[18]
|
Wicha, M.S., Liu, S. and Dontu, G. (2006) Cancer Stem Cells: An Old Idea—A Paradigm Shift. Cancer Research, 66, 1883-1890. https://doi.org/10.1158/0008-5472.CAN-05-3153
|
[19]
|
Dou, J. and Gu, N. (2010) Emerging Strategies for the Identification and Targeting of Cancer Stem Cells. Tumor Biology, 31, 243-253. https://doi.org/10.1007/s13277-010-0023-y
|
[20]
|
Murray, P.J. and Wynn, T.A. (2011) Obstacles and Opportunities for Understanding Macrophage Polarization. Journal of Leukocyte Biology, 89, 557-563. https://doi.org/10.1189/jlb.0710409
|
[21]
|
Solinas, G., Germano, G., Mantovani, A. and Allavena, P. (2009) Tu-mor-Associated Macrophages (TAM) as Major Players of the Cancer-Related Inflammation. Journal of Leukocyte Biolo-gy, 86, 1065-1073.
https://doi.org/10.1189/jlb.0609385
|
[22]
|
Spranger, S. (2016) Mechanisms of Tumor Escape in the Context of the T-Cell-Inflamed and the Non-T-Cell-Inflamed Tumor Microenvironment. International Immunology, 28, 383-391. https://doi.org/10.1093/intimm/dxw014
|
[23]
|
Xiao, Y., Ma, D., Zhao, S., et al. (2019) Multi-Omics Profiling Re-veals Distinct Microenvironment Characterization and Suggests Immune Escape Mechanisms of Triple-Negative Breast Cancer. Clinical Cancer Research, 25, 5002- 5014. https://doi.org/10.1158/1078-0432.CCR-18-3524
|
[24]
|
Chen, M., Sharma, A., Lin, Y., et al. (2019) Insluin and Epithelial Growth Factor (EGF) Promote Programmed Death Ligand 1(PD-L1) Production and Transport in Colon Cancer Stem Cells. BMC Cancer, 19, Article No. 153.
https://doi.org/10.1186/s12885-019-5364-3
|
[25]
|
Anders, C.K., Abramson, V., Tan, T. and Dent, R. (2016) The Evolution of Triple-Negative Breast Cancer: From Biology to Novel Therapeutics. American Society of Clinical Oncology Educational Book, 36, 34-42.
https://doi.org/10.1200/EDBK_159135
|
[26]
|
Chen, L. and Han, X. (2015) Anti-PD-1/PD-L1 Therapy of Human Cancer: Past, Present, and Future. Journal of Clinical Investigation, 125, 3384-3391. https://doi.org/10.1172/JCI80011
|
[27]
|
Xu, P., Xiong, W., Lin, Y., et al. (2021) Histone Deacetylase 2 Knockout Suppresses Immune Escape of Triple-Negative Breast Cancer Cells via Downregulating PD-L1 Expression. Cell Death & Disease, 12, Article No. 779. https://doi.org/10.1038/s41419-021-04047-2
|
[28]
|
Wu, B., Song, M., Dong, Q., et al. (2022) UBR5 Promotes Tumor Immune Evasion through Enhancing IFN-γ-Induced PDL1 Transcription in Triple Negative Breast Cancer. Theranostics, 12, 5086-5102.
https://doi.org/10.7150/thno.74989
|
[29]
|
Yamashita, N., Long, M., Fushimi, A., et al. (2021) MUC1-C Integrates Activation of the IFN-γ Pathway with Suppression of the Tumor Immune Microenvironment in Triple-Negative Breast Cancer. Journal for ImmunoTherapy of Cancer, 9, e002115. https://doi.org/10.1136/jitc-2020-002115
|
[30]
|
Hao, Q. and Tang, H. (2018) Interferon-γ and Smac Mimetics Synergize to Induce Apoptosis of Lung Cancer Cells in a TNFΑ-Independent Manner. Cancer Cell International, 18, Article No. 84. https://doi.org/10.1186/s12935-018-0579-y
|
[31]
|
Chen, X. and Cubillos-Ruiz, J.R. (2021) Endoplasmic Reticulum Stress Signals in the Tumour and Its Microenvironment. Nature Reviews Cancer, 21, 71-88. https://doi.org/10.1038/s41568-020-00312-2
|
[32]
|
Yao, X., Tu, Y., Xu, Y., et al. (2020) Endoplasmic Reticulum Stress-Induced Exosomal miR-27a-3p Promotes Immune Escape in Breast Cancer via Regulating PD-L1 Expression in Macrophages. Journal of Cellular and Molecular Medicine, 24, 9560-9573. https://doi.org/10.1111/jcmm.15367
|
[33]
|
Chen, D. and Mellman, I. (2017) Elements of Cancer Immunity and the Cancer-Immune Set Point. Nature, 541, 321-330. https://doi.org/10.1038/nature21349
|
[34]
|
Bagati, A., Kumar, S., Jiang, P., et al. (2021) Integrin αvβ6-TGFβ-SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer. Cancer Cell, 39, 54-67. https://doi.org/10.1016/j.ccell.2020.12.001
|
[35]
|
Wu, Y., Yi, Z., Li, J., et al. (2022) FGFR Blockade Boosts T Cell Infiltration into Triple-Negative Breast Cancer by Regulating Cancer-Associated Fibroblasts. Theranostics, 12, 4564-4580. https://doi.org/10.7150/thno.68972
|
[36]
|
Engel, J.B., Honig, A., Kapp, M., et al. (2014) Mechanisms of Tumor Immune Escape in Triple-Negative Breast Cancers (TNBC) with and without Mutated BRCA 1. Archives of Gynecology and Obstetrics, 289, 141-147.
https://doi.org/10.1007/s00404-013-2922-9
|
[37]
|
Yamaguchi, T., Wing, J.B. and Sakaguchi, S. (2011) Two Modes of Immune Suppression by Foxp3+ Regulatory T Cells under Inflammatory or Non-Inflammatory Conditions. Seminars in Immunology, 23, 424-430.
https://doi.org/10.1016/j.smim.2011.10.002
|
[38]
|
Zou, W. (2005) Immunosuppressive Networks in the Tumour En-vironment and Their Therapeutic Relevance. Nature Reviews Cancer, 5, 263-274. https://doi.org/10.1038/nrc1586
|
[39]
|
Quail, D.F. and Joyce, J.A. (2013) Microenvironmental Regulation of Tumor Progression and Metastasis. Nature Medicine, 19, 1423-1437. https://doi.org/10.1038/nm.3394
|
[40]
|
Joyce, J.A. and Pollard, J.W. (2009) Microenvironmental Regulation of Metastasis. Nature Reviews Cancer, 9, 239-252. https://doi.org/10.1038/nrc2618
|
[41]
|
Dvorak, K.M., Pettee, K.M., Rubinic-Minotti, K., et al. (2018) Carcinoma Associated Fibroblasts (CAFs) Promote Breast Cancer Motility by Suppressing Mammalian Diaphanous-Related For-min-2 (mDia2). PLOS ONE, 13, e0195278.
https://doi.org/10.1371/journal.pone.0195278
|
[42]
|
Picarda, E., Ohaegbulam, K.C. and Zang, X. (2016) Molecular Pathways: Targeting B7-H3 (CD276) for Human Cancer Immunotherapy. Clinical Cancer Research, 22, 3425-3431. https://doi.org/10.1158/1078-0432.CCR-15-2428
|
[43]
|
Cheng, N., Bei, Y., Song, Y., et al. (2021) B7-H3 Aug-ments the Pro-Angiogenic Function of Tumor-Associated Macrophages and Acts as a Novel Adjuvant Target for Tri-ple-Negative Breast Cancer Therapy. Biochemical Pharmacology, 183, Article ID: 114298. https://doi.org/10.1016/j.bcp.2020.114298
|
[44]
|
Chaturvedi, P., Gilkes, D.M., Takano, N., et al. (2014) Hypox-ia-Inducible Factor-Dependent Signaling between Triple- Negative Breast Cancer Cells and Mesenchymal Stem Cells Promotes Macrophage Recruitment. Proceedings of the National Academy of Sciences of the United States of America, 111, E2120-E2129.
https://doi.org/10.1073/pnas.1406655111
|
[45]
|
Li, X., Chen, M., Lu, W., et al. (2021) Targeting FAPα-Expressing Tumor-Associated Mesenchymal Stromal Cells Inhibits Triple-Negative Breast Cancer Pulmonary Metastasis. Cancer Letters, 503, 32-42.
https://doi.org/10.1016/j.canlet.2021.01.013
|
[46]
|
Tsai, Y.-F., Huang, C.-C., Lin, Y.-S., et al. (2021) Interleukin 17A Promotes Cell Migration, Enhances Anoikis Resistance, and Creates a Microenvironment Suitable for Triple Nega-tive Breast Cancer Tumor Metastasis. Cancer Immunology, Immunotherapy, 70, 2339-2351. https://doi.org/10.1007/s00262-021-02867-x
|
[47]
|
Wang, R., Lou, X., Feng, G., et al. (2019) IL-17A-Stimulated Endothelial Fatty Acid β-Oxidation Promotes Tumor Angiogenesis. Life Sciences, 229, 46-56. https://doi.org/10.1016/j.lfs.2019.05.030
|
[48]
|
Masuda, H., Baggerly, K.A., Wang, Y., et al. (2013) Differential Response to Neoadjuvant Chemotherapy among 7 Triple-Negative Breast Cancer Molecular Subtypes. Clinical Cancer Research, 19, 5533-5540.
https://doi.org/10.1158/1078-0432.CCR-13-0799
|
[49]
|
Sun, X., Wang, M., Wang, M., et al. (2020) Metabolic Re-programming in Triple-Negative Breast Cancer. Frontiers in Oncology, 10, Article 428. https://doi.org/10.3389/fonc.2020.00428
|
[50]
|
Tsai, T.-H., Yang, C.-C., Kou, T.-C., et al. (2021) Overexpression of GLUT3 Promotes Metastasis of Triple-Negative Breast Cancer by Modulating the Inflammatory Tumor Microenviron-ment. Journal of Cellular Physiology, 236, 4669-4680. https://doi.org/10.1002/jcp.30189
|