MPV、FIB、UA水平与冠心病的关系及研究进展Progress and Relationship between Level of MPV, FIB, UA and Coronary Heart Disease
贾梅, 刘志跃, 杜秀丽
冠心病, 血小板平均体积, 纤维蛋白原, 尿酸, 预测Coronary Heart Disease, Mean Platelet Volume, Fibrinogen, Uric Acid, Prediction
《Advances in Clinical Medicine》, Vol.5 No.2, 2015-06-19
Coronary heart disease is a serious threat to human health, it is a disease caused by a variety of factors, in addition to main risk factors, in recent years, a large number of studies have found that mean platelet volume, fibrinogen and uric acid is closely related to the occurrence, development and prognosis of coronary heart disease. Mean platelet volume is a biological indicator of platelet activation, fibrinogen is an important clotting factor, uric acid is an important inflammatory cyto-kines, through different mechanisms result in thrombosis, and participate in the occurrence and development of atherosclerosis. Combined detection of three indicators, it is possible to improve its predictive value of early diagnosis and the severity of coronary lesions in coronary heart disease. This paper reviews the progress and relationship between level of mean platelet volume, fibrinogen, uric acid and coronary heart disease.