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Wieland, S.F., Spangenberg, H.C., Thimme, R., Purcell, R.H. and Chisari, F.V. (2004) Expansion and contraction of the hepatitis B virus transcriptional template in infected chimpanzees. Proceedings of the National Academy of Sciences of the United States of America, 101, 2129-2134.

被以下文章引用:

• 标题: 乙肝病毒cccDNA的研究现状The Research Status of Hepatitis B Virus cccDNA

  作者: 王宁

  关键字: 乙型肝炎病毒, 松弛环状双链DNA, 共价闭合环状DNAHBV, rcDNA, cccDNA

  期刊名称: 《Immunology Studies》, Vol.3 No.2, 2015-06-26

  摘要: 乙型肝炎病毒(HBV)是一种小DNA病毒，共价闭合环状DNA (cccDNA)是HBV的原始复制模板，对乙肝病毒的复制及感染状态的建立具有重要意义。本文旨在对近年来有关cccDNA的形成、常用检测方法、抗病毒药物对其的影响等方面的进展作一综述报道。 The hepatitis B virus (HBV) is a kind of small DNA virus. The original template of covalently closed circular DNA (cccDNA) HBV is very important for the replication of the hepatitis B virus and the establishment of infection status. The progress of the formation of cccDNA, the methods of detection and the impact of antiviral drugs were reviewed in this paper.