H. Ma, X. Song, T. J. Harrison, et al. Hepatitis E virus ORF3 antigens derived from genotype 1 and 4 viruses are detected with varying efficiencies by an anti-HEV enzyme immunoassay. Journal of Medical Virology, 2011, 83(5): 827-832.
戊型肝炎病毒的基因组结构及生物学功能研究进展Development of Genomic Structure and Function of Hepatitis E Virus
雷雅昕, 刘鹏, 王玲
戊型肝炎病毒, 基因结构, 开放读码框, 顺反应元件Hepatitis E Virus (HEV); Gene Structure; Open Reading Frame (ORF); Cis-Reactive Elements (CRE)
《Advances in Microbiology》, Vol.2 No.1, 2013-03-27
Hepatitis E virus (HEV) is one of the most important pathogens of acute viral hepatitis prevailing in developing countries. There are four major genotypes of mammalian HEV, genotype 1 and 2 are restricted to human infection, and induce epidemic hepatitis E which is mainly transmitted by contaminated water; whereas genotype 3 and 4 are zoonotic causing sporadic cases which are common in developed countries. In recent years, much more attention has been paid to the structures of viral genes and the functions of viral proteins. The research progress achieved in such field will help us uncover the veil of HEV in pathogenesis and infection.