Oppling, V., Muller H. and Becht, H. (1991) Heterogeneity of the Antigenic Site Responsible for the Induction of Neutralizing Antibodies in Infectious Bursal Disease Virus. Archives of Virology, 119, 211-223.
一株传染性法氏囊病毒野毒株的分离与鉴定Identification and Isolation of a Wild Strain of Infectious Bursal Disease Virus
付梦姣, 王永强, 李晓齐, 曹红, 陈福勇, 郑世军
传染性法氏囊病毒, VP2, 毒力Infectious Bursal Disease Virus, VP2, Virulence
《Asian Case Reports in Veterinary Medicine》, Vol.5 No.1, 2016-01-29
The kidney, spleen and bursa of fabricius samples were collected from diseased chickens on a farm in Beijing suburban areas. A wild strain of infectious bursal disease virus (IBDV), temporarily called BY-2015-1, was isolated by embryonic inoculation and identified via RT-PCR assay and sequence analysis. Gene sequence analysis of VP2 showed that the homology between BY-2015-1 and OKYM strains was 97.7%. The amino acid sequence analysis of VP2 high variable region indicated that BY-2015-1 isolate had similar characteristics of very virulent strains, suggesting that the isolate might be a circulating virulent strain in the flocks on the farm. The isolation and identification of IBDV BY-2015-1 strain would help to prevent and control IBDV in the local areas.