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Shaw, J.E., Sicree, R.A. and Zimmet, P.Z. (2010) Global Estimates of the Prevalence of Diabetes for 2010 and 2030. Diabetes Research and Clinical Practice, 87, 4-14.
http://dx.doi.org/10.1016/j.diabres.2009.10.007

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  • 标题: 2型糖尿病多器官自身免疫反应机制研究进展The Research of Type 2 Diabetes Multiorgan Autoimmune Reaction Mechanism

    作者: 张琨, 寿伟臻

    关键字: 2型糖尿病, 自身免疫, 反应机制Type 2 Diabetes, Autoimmunity, Reaction Mechanism

    期刊名称: 《Advances in Clinical Medicine》, Vol.6 No.1, 2016-03-03

    摘要: 在糖尿病患者中,2型糖尿病的发病人数占糖尿病总数的90%以上。医学界较统一的观点认为免疫介导的胰岛功能损伤是1型糖尿病的发病机制,胰岛素受体功能缺陷以及受体后信号转导障碍是2型糖尿病的发病机制。但是免疫机制在2型糖尿病的发生以及发展过程中也起着很重要的作用,虽然目前关于这方面的研究还不是很多,但是免疫机制对2型糖尿病重要作用必将成为新的研究热点。 In patients with diabetes, the number of the onset of type 2 diabetes accounts for more than 90% of the total number of diabetes. The medical profession unified a view that immune-mediated islet function damage is the pathogenesis of type 1 diabetes. The function of insulin receptor defects and post receptor signal transduction disorder is the pathogenesis of type 2 diabetes mellitus. But the immune mechanism in the process of the occurrence and development of type 2 diabetes also plays an important role. Though there is not much research on this subject, the immune mechanism of type 2 diabetes important role will become a new research hotspot.