标题:
龙葵素抗肿瘤作用研究进展Progress of Anti-Cancer Function of Solanine
作者:
李兰香, 熊兴耀, 杨青
关键字:
糖苷生物碱, 龙葵素, 抗肿瘤, 细胞凋亡Glycoalkaloids, Solanine, Anti-Cancer, Apoptosis
期刊名称:
《Hans Journal of Food and Nutrition Science》, Vol.5 No.2, 2016-05-09
摘要:
龙葵素是一种重要的糖苷生物碱，具有多种生物学作用，能对多种疾病起到防治的作用，其中包括抗肿瘤作用。龙葵素在抗肿瘤作用从细胞和分子途径诱导细胞的凋亡和自噬，使癌细胞的迁移、浸润、血管发生一起转移能力受到抑制。因此，本文就龙葵素对各种癌细胞的抑制作用及其作用机制进行了综述。Solanine is an important glycoalkaloid, with a variety of biological effects. It plays a role in pre-vention and treatment of many diseases, including its anti-tumor effect. Solanine exhibits its an-ti-tumor effect through regulation several cellular and molecular pathways which induce cell apoptosis and autophagy, and inhibit cancer cells’ migration, invasion, angiogenesis and metastasis. Therefore, anti-cancer effects of solanine and its mechanism are reviewed in this article.