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外周血中性粒细胞与淋巴细胞比值(NLR)与结直肠癌不同期别预后的研究Study of Perpheral Neutrophil to Lymphocyte Ratio (NLR) in Different Stages Prognosis of Colorectal Cancer
尹端端, 王真真, 杨雁鸿, 李倩影, 冯博, 冯悦, 王小玉
结直肠癌, 中性粒细胞/淋巴细胞比值(NLR), 预后因素, 总生存期, 无进展生存期Colorectal Cancer, Neutrophil/Lymphocyte Ratio (NLR), Prognostic Factors, Overall Survival, Progression Free Survival
《Asian Case Reports in Oncology》, Vol.5 No.2, 2016-07-29
目的：探讨NLR评价结直肠癌不同分期预后的价值，为结直肠癌患者开展个体化治疗、延长生存期提供理论依据。方法：统计符合要求的结直肠癌患者，依据ROC曲线取得NLR = 2.54值为本课题的研究截点,并分为低、高NLR两组，比较两组患者在临床特征及预后生存期的差异。结果：单因素分析证实：低、高NLR组在除年龄外的其他基本特征间差异无统计学意义(P
Objective: The study investigates NLR to evaluate at different stages prognosis of colorectal cancer, then provides individualized treatment and prolong survival theoretical basis for colorectal cancer patients. Methods: Add up all colorectal cancer patients who meet the requirements, and choose NLR = 2.54 as study intercept according to the ROC curve. All the patients were divided into low NLR and high NLR groups, then clinical features and prognosis of survival of the two groups would be compared. Results: Univariate analysis showed that: There was no significant difference in the basic features besides age between low NLR and high NLR groups (P