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Hsu, Y.L., Kuo, P.L. and Lin, L.T. (2005) Asiatic Acid, a Triterpene, Induces Apoptosis and Cell Cycle Arrest through Activation of Extracellular Signal-Regulated Kinase and p38 Mitogen-Activated Protein Kinase Pathways in Human Breast Cancer Cells. Journal of Pharmacology and Experimental Therapeutic, 313, 333-344. http://dx.doi.org/10.1124/jpet.104.078808

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• 标题: 积雪草酸及其衍生物抗肿瘤活性的研究进展Advances in Studies on Antitumor Activities of Asiatic Acid and Its Derivatives

  作者: 孟艳秋, 宁梓廷, 杨丽娜, 于婷婷, 张伟晨, 潘洪双

  关键字: 积雪草酸, 衍生物, 抗肿瘤Asiatic acid, Derivatives, Antitumor

  期刊名称: 《Hans Journal of Medicinal Chemistry》, Vol.4 No.2, 2016-10-24

  摘要: 积雪草酸是一种乌苏烷型五环三萜酸，主要来源于伞形科植物积雪草，具有广泛的药理活性，其抗肿瘤活性尤为显著。本文对积雪草酸及其衍生物的抗肿瘤活性的研究进展进行综述并进行展望。 Asiatic acid is a type of pentacyclic triterpene acid from Centella asiatica. It has been found that Asiatic acid has many kinds of pharmacological effects, especially its antitumor activity. In this paper, the research progress of antitumor activity of asiatic acid and its derivatives has been re-viewed and forecasted.