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De Filippis, L. and Binda, E. (2012) Concise review: Self-renewal in the central nervous system. Neural stem cells from embryo to adult. Stem Cells Translational Medicine, 1, 298-308.

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  • 标题: 神经干细胞与脑缺血损伤Neural Stem Cells and Cerebral Ischemia Injury

    作者: 田兆华, 刘柏炎

    关键字: 神经干细胞, 脑缺血损伤Neural Stem Cells; Cerebral Ischemia Injury

    期刊名称: 《Asian Case Reports in Vascular Medicine》, Vol.3 No.1, 2014-02-11

    摘要: 目的:探讨神经干细胞的定义、移植分化及调控因素,以及与脑缺血之间的关系。方法:通过阐述神经干细胞的定义及生物学特性,结合神经干细胞移植及微环境调控,进一步将神经干细胞与脑缺血损伤修复机制加以联系。结果:神经干细胞能够修复脑缺血损伤,但要克服定向分化、炎症及排斥反应等问题。结论:神经干细胞移植可用于脑缺血损伤神经修复。 Objective: To explore the definition, transplantation, differentiation, regulator factors and the relation of neural stem cells (NSCs) and cerebral ischemia injury. Methods: To expound the definition and biological characteristics of NSCs, unite NSCs transplantation, micro environment control and to contact NSCs and cerebral ischemia injury mechanism. Results: Neural stem cells may repair cerebral ischemia injury, but overcome the problem of directional differentiation, inflammation and reject reaction. Conclusion: The transplantation of neural stem cells can be used in the neural restoration of the cerebral ischemia injury.