标题:
尿素通道蛋白B的转运特性Transport Characteristics of Urea Transporter-B
作者:
钟丹丹, 杨宝学
关键字:
尿素通道蛋白B, 尿素, 尿素类似物, NH3, 水UT-B; Urea; Urea Analogues; Ammonia; Water
期刊名称:
《Journal of Physiology Studies》, Vol.2 No.1, 2014-04-23
摘要:
尿素通道蛋白B(urea transporters B, UT-B)主要表达在红细胞和一些上皮及内皮细胞膜，介导尿素的跨膜转运。近年来研究发现UT-B亦参与其他物质的转运，如水、NH3和尿素类似物等，提示UT-B还可以作为水和气体通道。本文主要阐述UT-B对这些物质的转运特性，并探究其可能的生理学意义。
Urea transporter UT-B is highly expressed in the membrane of erythrocytes and some epithelial and endothelial cells, in which UT-B facilitates urea transport. Recently, studies find that water, ammonia and urea analogues can also be transported by UT-B. This review mainly focuses on the transport characteristics of UT-B, and the possible physiological significance will be discussed as well.