标题:
维生素D在自闭症中作用的研究进展Role of Vitamin D in Autism
作者:
贾飞勇, 单玲, 冯俊燕, 王冰, 李洪华, 杜琳
关键字:
自闭症, 维生素D, 免疫调节, 氧化应激, 基因稳定Autism, Vitamin D, Immunologic Regulation, Oxidative Stress, Genomic Stability
期刊名称:
《International Journal of Psychiatry and Neurology》, Vol.3 No.4, 2014-11-05
摘要:
自闭症临床表现为行为障碍，存在着免疫异常、氧化应激改变甚至基因异常。自闭症患儿普遍存在着维生素D缺乏。维生素D除了传统的钙磷代谢调节作用外，尚具有免疫调节、增加谷胱甘肽的合成及基因稳定等功能。我们最新的研究表明维生素D能够改善自闭症患儿的行为，提示维生素D参与了自闭症的致病过程。本文就维生素D在自闭症中的可能作用的研究进展作一综述。Autism is characterized by abnormal immunology, altered oxidative stress and even genetic ab-normality in addition to behavioral problems. Vitamin D deficiency is ubiquity in children with autism. Vitamin D plays a role in regulating immune, up-regulating glutathione, and controlling genome in addition to traditional action on calcium and phosphate regulation. We recently reported that vitamin D supplementation could improve the behavioral manifestations in autistic child, which illustrated that vitamin D was involved in the pathogenesis of autism. Herein we summarize the research progress of the role of vitamin D in autism.