标题:
环形DNA分子构象统计Conformations of DNA Loop
作者:
张兴华, 肖弘毅
关键字:
DNA环, 构象, 蒙特卡洛模拟DNA Loop; Conformation; Monte Carlo Simulation
期刊名称:
《Applied Physics》, Vol.4 No.2, 2014-03-14
摘要:
DNA环的形成和性质是生物物理以及软物质物理关注的基本问题。本文以蠕虫状链为模型,应用蒙特卡洛方法模拟了锚定在蛋白质上的DNA环的构象统计。给出了DNA环在不同长度序列情况下的择优构象状态,讨论了不同构象情况下DNA分子对锚定点的作用力。The formation and property of DNA loop are the basic problems of biophysics and soft matter physics. In present work, the conformational statistics is studied by Monte Carlo method based on the wormlike chain model. The priority conformational state for the different length of DNA loop is predicted and the force acting on the grafting point is also discussed.