[1]
|
《中国心血管健康与疾病报告2020》概述[J]. 中国心血管病研究, 2021, 19(7): 582-590.
|
[2]
|
Clemente, J.C., Ursell, L.K., Parfrey, L.W., et al. (2012) The Impact of the Gut Microbiota on Human Health. An Integrative View. Cell, 148, 1258-1270. https://doi.org/10.1016/j.cell.2012.01.035
|
[3]
|
Adak, A. and Khan, M.R. (2019) An Insight into Gut Microbiota and Its Functionalities. Cellular and Molecular Life Sciences, 76, 473-493. https://doi.org/10.1007/s00018-018-2943-4
|
[4]
|
高中山, 任明, 刘杏利, 等. 短链脂肪酸在冠心病防治中的研究进展[J]. 临床心血管病杂志, 2021, 37(11): 1062-1066.
|
[5]
|
Hu, T., Wu, Q., Yao, Q., et al. (2022) Short-Chain Fatty Acid Metabolism and Multiple Effects on Cardiovascular Diseases. Ageing Research Reviews, 81, Article ID: 101706. https://doi.org/10.1016/j.arr.2022.101706
|
[6]
|
Cai, Y., Folkerts, J., Folkerts, G., et al. (2020) Microbiota-Dependent and-Independent Effects of Dietary Fibre on Human Health. British Journal of Pharmacology, 177, 1363-1381. https://doi.org/10.1111/bph.14871
|
[7]
|
Chang, Y., Chen, Y., Zhou, Q., et al. (2020) Short-Chain Faty Acids Accompanying Changes in the Gut Microbiome Contribute to the Development of Hypertension in Patients with Preclampsia. Clinical Science, 134, 289-302. https://doi.org/10.1042/CS20191253
|
[8]
|
Chen, L., He, F.J., Dong, Y., et al. (2020) Modest Sodium Reduction Increases Circulating Short-Chain Faty Acids in Untreated Hypertensives: A Randomized, Double-Blind, Placebo-Control Led Trial. Hypertension, 76, 73-79. https://doi.org/10.1161/HYPERTENSIONAHA.120.14800
|
[9]
|
Zhao, L., Zhang, F., Ding, X., et al. (2018) Gut Bacteria Selectively Promoted by Dietary Fibers Aleviate Type 2 Diabetes. Science, 359, 1151-1156. https://doi.org/10.1126/science.aao5774
|
[10]
|
Jadhay, K., Xu, Y., Xu, Y.Y., et al. (2018) Reversal of Metabolic Disorders by Pharmacological Activation of Bile Acid Receptors TGR5 and FXR. Molecular Metabolism, 9, 131-140. https://doi.org/10.1016/j.molmet.2018.01.005
|
[11]
|
Perino, A., Demagny, H., Velazquez-Villegas, L. and Schoonjans, K. (2021) Molecular Physiology of Bile Acid Signaling in Health, Disease, and Aging. Physiological Reviews, 101, 683-731. https://doi.org/10.1152/physrev.00049.2019
|
[12]
|
Gram, A. and Kowalewski Mariusz, P. (2022) Molecular Mechanisms of Lipopolysaccharide (LPS) Induced Inflammation in an Immortalized Ovine Luteal Endothelial Cell Line (OLENDO). Veterinary Sciences, 3, Article 99. https://doi.org/10.3390/vetsci9030099
|
[13]
|
Mils, E.L., Ryan, D.G., Prag, H.A., et al. (2018) Itaconate Is an Anti-In-Flammatory Metabolite That Activates Nrf2 via Alkylation of KEAP1. Nature, 556, 113-117. https://doi.org/10.1038/nature25986
|
[14]
|
Zerbst-Boroffka, I., Kamaltynow, R.M., Harjes, S., et al. (2005) TMAO and Other Organic Osmolytes in the Muscles of Amphipods (Crustacea) from Shallow and Deep Water of Lake Baikal. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 142, 58-64. https://doi.org/10.1016/j.cbpa.2005.07.008
|
[15]
|
Ramireddy, L., Tsen, H.Y., Chiang, Y.C., et al. (2021) The Gene Expression and Bioinformatic Analysis of Choline Trimethylamine-Lyase (CutC) and Its Activating Enzyme (CutD) for Gut Microbes and Comparison with Their TMA Production Levels. Current Research in Microbial Sciences, 2, 35-43. https://doi.org/10.1016/j.crmicr.2021.100043
|
[16]
|
Mu, H.N. and Zhao, X.H. (2023) Choline and Trimethylamine N-Oxide Supplementation in Normal Chow Diet and Western Diet Promotes the Development of Atherosclerosis in Apoe Mice Through Different Mechanisms. International Journal of Food Sciences and Nutrition, 142, 11-13.
|
[17]
|
Gregory, J.C, Buffa, J.A, Org, E, et al. (2015) Transmission of Atherosclerosis Susceptibility with Gut Microbial Transplantation. Journal of Biological Chemistry, 290, 5647-5660. https://doi.org/10.1074/jbc.M114.618249
|
[18]
|
Amrein, M., Li, X.S., Walter, J., et al. (2022) Gut Microbiota-Dependent Metabolite Trimethylamine N-Oxide (TMAO) and Cardiovascular Risk in Patients with Suspected Functionally Relevant Coronary Artery Disease (FCAD). Clinical Research in Cardiology, 111, 692-704. https://doi.org/10.1007/s00392-022-01992-6
|
[19]
|
熊筱伟, 穆利英, 付强, 等. 老年患者血浆氧化三甲胺水平与颈动脉斑块负荷的关系研究[J]. 中华老年心脑血管病杂志, 2022, 24(6): 568-570
|
[20]
|
刘艳琪, 郑冠群, 陈志贤, 等. 血浆氧化三甲胺与冠心病的相关性及对冠心病患者预后的影响[J]. 实用临床医学杂志, 2022, 26(24): 90-96.
|
[21]
|
Okataviono, Y.H., Dyah Lamara, A., et al. (2023) The Roles of Trimethylamine-N-Oxide in Atherosclerosis and Its Potential Therapeutic Aspect: A Literature Review. Biomolecules, 133, 25-28. https://doi.org/10.17305/bb.2023.8893
|
[22]
|
Wang, B.Y., Qiu, J., Liang, J.F., et al. (2021) Gut Metabolite Trimethylamine-N-Oxide in Atherosclerosis: from Mechanism to Therapy. Frontiers in Cardiovascular Medicine, 9, Article 723886. https://doi.org/10.3389/fcvm.2021.723886
|
[23]
|
Li, Y., Zhang, L., Ren, P., et al. (2021) Qing-Xue-Xiao-Zhi Formula Attenuates Atherosclerosis by Inhibiting Macrophage Lipid Accumulation and Inflammatory Response via TLR4/NF-Kb Pathway Regulation. Phytomedicine, 93, Article ID: 153812. https://doi.org/10.1016/j.phymed.2021.153812
|
[24]
|
Wang, Z.N. and Zhao, Y.Z. (2018) Gut Microbiota Derived Metabolites in Cardiovascular Health and Disease. Protein & Cell, 9, 416-431. https://doi.org/10.1007/s13238-018-0549-0
|
[25]
|
Koeth, R.A., Wang, Z., Levison, B.S., et al. (2013) Intestinal Microbiota Metabolism of L-Carnitine, A Nutrient in Red Meat, Promotes Atherosclerosis. Nature Medicine, 19, 576-585. https://doi.org/10.1038/nm.3145
|
[26]
|
Wang, Z., Klipfelle Bennett, B.J., et al. (2011) Gut Flora Metabolism of Phosphatidylcholine Promotes Cardiovascular Disease. Nature, 472, 57-63. https://doi.org/10.1038/nature09922
|
[27]
|
丁琳, 张恬恬, 薛长湖, 等. 氧化三甲胺诱导的动脉粥样硬化与胆汁酸代谢有关[C]//中国食品科学技术学会第十五届年会论文摘要集. 2018: 242-243.
|
[28]
|
Brunt Vienna, E., Gioscia-Ryan Rachel, A., et al. (2020) Trimethylamine-N-Oxide Promotes Age-Related Vascular Oxidative Stress and Endothelial Dysfunction in Mice and Healthy Humans. Hypertension, 76, 101-112. https://doi.org/10.1161/HYPERTENSIONAHA.120.14759
|
[29]
|
Ma, G., Pan, B. and Chen, Y. (2017) Trimethylamine N-Oxide in Atherogenesis: Impairing Endothelial Self-Repair Capacity and Enhancing Monocyte Adhesion. Bioscience Reports, 37, BSR20160244. https://doi.org/10.1042/BSR20160244
|
[30]
|
Huang, W., Liu, Y., Li, L., et al. (2012) HMGB1 Increases Permeability of the Endothelial Cell Monolayer via RAGE and Src Family Tyrosine Kinase Pathways. Inflammation, 35, 350-362. https://doi.org/10.1007/s10753-011-9325-5
|
[31]
|
Formers, H. and Reinhardt, C. (2019) The Gut Microbiota—A Modulator of Endothelial Cell Function and a Contributing Environmental Factor to Arterial Thrombosis. Expert Review of Hematology, 7, 541-549. https://doi.org/10.1080/17474086.2019.1627191
|
[32]
|
Zhu, W., Gregory, J.C., Org, E., et al. (2016) Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk. Cell, 165, 111-124. https://doi.org/10.1016/j.cell.2016.02.011
|
[33]
|
娄焕堃, 赵玲, 王怡练, 等. 血清氧化三甲胺与冠心病的相关性研究[J]. 临床医学心血管疾病, 2021, 18(11): 70-72, 77.
|
[34]
|
Xiong, X.W., Zhou, J., et al. (2022) The Associations Between TMAO-Ralated Metabolites and Blood Lipids and the Potential Impact of Rosuvastatin Therapy. Lipids in Health and Disease, 21, Article No. 60. https://doi.org/10.1186/s12944-022-01673-3
|
[35]
|
Ge, X.Y., Zheng, L., et al. (2020) The Gut Microbial Metabolite Trimethylamine N-Oxide and Hypertension Risk: A Systematic Review and Dose-Response Meta-Analysis. Advances in Nutrition, 11, 66-76. https://doi.org/10.1093/advances/nmz064
|
[36]
|
Ufnal, M., Jazwiec, R., Dadlez, M., et al. (2014) Trimethylamine-N-Oxide: A Carnitine-Derived Metabolite That Prolongs the Hypertensive Effect of Angiotensin II in Rats. Canadian Journal of Cardiology, 30, 1700-1705. https://doi.org/10.1016/j.cjca.2014.09.010
|
[37]
|
Zhang, Y.N., Wang, S.M., et al. (2021) Plasm Trimethylamine-N-Oxide Level and Association with Lesion Severity in Coronary Heart Disease Patients with Type 2 Diabetes Mellitus. Chinese Journal of Cardiology, 49, 680-686.
|
[38]
|
Krisshna, S., O’Connor, L.E., Wang, Y., et al. (2021) Adopting a Mediterranean-Style Eating Pattern with Low, But Not Moderate, Unprocessed, Lean Red Meat Intake Reduces Fasting Serum Trimethylamine N-Oxide (TMAO) in Adults Who Are Overwight or Obese. The British Journal of Nutrition, 128, 21-22. https://doi.org/10.1017/S0007114521004694
|
[39]
|
Shih, D.M., Wang, Z., Lee, R., et al. (2015) Flavin Containing Monooxygenase 3 Exerts Broad Effects on Glucose and Lipid Metabolism and Atherosclerosis. Journal of Lipid Research, 56, 22-37. https://doi.org/10.1194/jlr.M051680
|
[40]
|
Wang, Z., Klipfell, E., Bennett, B.J., et al. (2011) Gut Flora Metabolism of Phosphatidylcholine Promotes Cardiovascular Disease. Nature, 472, 57-63. https://doi.org/10.1038/nature09922
|
[41]
|
张鑫宇, 蓝涛华, 曾巧煌, 等. 中医药通过调节肠道菌群分别结构干预冠心病的研究进展[J]. 中西医结合心脑血管病杂志, 2022, 20(15): 2762-2767.
|
[42]
|
卓延玲. 一种通过调节肠道菌群减轻血管炎症的姜黄素乳杆菌配方的开放及研究[J]. 医药科技卫生, 2023(1): 1-57.
|