基本情况
何睿,复旦大学教授,博士研究生导师。
研究领域
1.CD4 T细胞分化和归巢的分子机制的研究
2.过敏性疾病和自身免疫病的发病机理的研究
3.炎症相关肿瘤发生机制的研究
教育背景
1999.9-2004.7,博士,中国协和医科大学
1994.9-1999.7,学士,华西医科大学
工作经历
2012.12-至今,教授、博士生导师,复旦大学上海医学院免疫学系
2001.1-2012.11,副研究员、博士生导师,复旦大学上海医学院免疫学系
2004.9-2009.10,博士后,哈佛大学波士顿儿童医院免疫学系
论文发表
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Wang LM, Zhao LN, Lv JY,Yin QL, Liang XY,
Chu YW and He R*. BLT1-dependent alveolar recruitment of CD4+CD25+ Foxp3+ regulatory
T cells is important for resolution of acute lung injury.Am J RespirCrit Care
Med2012,Nov 15;186(10):989-98 IF:11.08 通讯作者
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Oyoshi MK*, He R* (共同第一作者), Li
Y, Mondal, S, Yoon J, Afshar R, Chen M,Lee DM, Luo HR, Luster AD, Cho JS,
Miller LS, Larson A, Murphy GF and Geha RS. LTB4 driven neutrophil recruitment
to the skin is essential for allergic skin inflammationImmunity 2012
Oct19;37(4):747-58, IF:21.637
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He R, Oyoshi MK, Wang JY, Hodge MR, Jin
H,and Geha RS.The prostaglandin D(2) receptor CRTH2 is important for allergic
skin inflammation after epicutaneous antigen challenge. J Allergy
ClinImmunol.2010; 126(4):784-90 IF:9.77
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Oyoshi MK,He R, Elkhal A,Kawamoto S, Lewis
C, Kanaoka Y, Austen KF, and Geha RS.Eosinophil-derivedLTC4 signals via CysLT2R
to promote skin thickening and collagen deposition in a mouse model of allergic
skin inflammation. ProcNatlAcadSci U S A 2012;109(13):4992-7 IF:9.68
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He R, Kim HY, Yoon J, Oyoshi MK,
MacGinnitie A, Goya S , Bryce P, Freyschmidt EJ, McKenzie AJ, Umetsu DT, Oettgen
HC and Geha RS. Exaggerated IL-17 response to epicutaneous sensitization
mediates airway inflammation in the absence of IL-4 and IL-13. J Allergy
ClinImmunol 2009; 124(4):761-770.e1 IF:9.77
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He R and Geha RS. Thymic Stromal
Lymphopoietin.Ann N Y Acad Sci. 2010;1183:13-24 IF:2.3
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Oyoshi MK,Elkhal A, Kumar L, Scott J,
Koduru S, He R, Leung DY, Howell MD, Oettgen HC, Murphy GF, and Geha RS. IL-17
promotes dissemination of vaccinia virus in a mouse model of eczema vaccinatum.
ProcNatlAcadSci U S A 2009;106(35):14954-9 IF:9.68
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Oyoshi MK, He R, Kumar L, Yoon J and Geha
RS. Cellular and molecular mechanisms in Atopic dermatitis. Advances in
Immunology2009;102:135-226 IF:6.26
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He R, Oyoshi MK, Garibyan L, Kumar L,
Ziegler SF and Geha RS. TSLP acts on infiltrating effector T cells to drive
allergic skin inflammation. ProcNatlAcadSci U S A 2008; 105(33):11875-80 IF:9.68
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He R, Oyoshi MK, Jin H, Geha RS.
Epicutaneous antigen exposure induces a TH17 response that drives airway
inflammation after inhalation challenge. ProcNatlAcadSci USA 2007; 104(40):
15817-22 IF:9.68
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Jin H, He R*(co-first author),Oyoshi MK,
Geha RS. Animal models of atopic dermatitis. J Invest Dermatol;2009;
129(1):31-40 IF:4.66
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Yalcindag A, He R*(co-first author),
Laouini D, Alenius H, Carroll M, Oettgen HC, Geha RS. Thecomplement component
C3 plays a critical role in both Th1 and Th2 responses to antigen. J Allergy
ClinImmunol. 2006; 117(6):1455-61. IF:9.77*= Equal first author
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Elkhal A, Pichavant M, He R, Scott J, Meyer
E, Goya S, Geha RS, Umetsu DT. CD1d restricted natural killer T cells are not
required for allergic skin inflammation. J Allergy ClinImmunol.
2006;118(6):1363-8 IF:9.77
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Xu ZS, Liu YJ, Lv LL, Han ZB, He R, Lu SH,
Wang T, Xu B, Chen ZZ, Han ZC. Bone marrow stromal cells transduced with human
hemangiopoietin gene support hematopoiesis in vitro. Haematologica.
2005;90(2):157-65 IF:5.52
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He R, Liu B, Yang C, Yang RC, Tobelem G,
Han ZC. Inhibition of K562 leukemia angiogenesis and growth by expression of
antisense vascular endothelial growth factor (VEGF) sequence. Cancer Gene Ther.
2003;10(12):879-86 IF:3