基本情况
郑世军,免疫学博士,中国农业大学特聘教授、博士生导师,国家杰出青年基金获得者,新世纪百千万人才工程国家级人选,中国农科院教学名师,全国华侨侨眷先进个人,获国务院特殊专家津贴。
研究领域
目前主要从事抗感染免疫的分子机理以及畜禽传染病免疫防制的研究
教育背景
2000年12月至2005年6月
博士后,美国宾夕法尼亚大学
1996年8月至2000年12月
博士,美国麻省大学
1987年9月至1990年7月
硕士,中国农业大学
1982年9月至1987年7月
学士,中国农业大学
工作经历
2005年7月至今 特聘教授,中国农业大学
2000年12月至2005年6月
博士后,美国宾夕法尼亚大学
1996年8月至2000年12月
研究助理,美国麻省大学
1993年1月至1996年8月
讲师,中国农业大学
1990年7月至1993年1月
助教,中国农业大学
学术兼职
中国农学会理事会理事
中国免疫学会北京市免疫学分会理事
中国免疫学会动物免疫学分会常务理事
中国畜牧兽医学会动物传染病学分会常务理事
农业生物技术国家重点实验室研究员
全国动物疫病防控专家委员会委员
所获荣誉
国家杰出青年基金获得者
新世纪百千万人才工程国家级人选
获国务院特殊专家津贴
中国农科院教学名师
全国华侨侨眷先进个人
主要论著
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Zhao D, Li J, Wang Y,
Li X, Gao L, Cao H, and Zheng SJ*. Critical role for G3BP1 ininfectious bursal disease virus (IBDV)-induced
stress granule formation and viral replication. Vet Microbiology 2020,
248: 108806. doi.org/10.1016/j.vetmic.2020.108806.
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Li J and Zheng SJ*. Role of microRNAs in host
defense against infectious bursal disease virus (IBDV) infection: a hidden front line. Viruses 2020, May 14, 12(543): 1-18. doi:10.3390/v12050543
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Duan X, Zhao M, Li X, Gao L, Cao H, Wang Y*, and Zheng SJ*. gga-miR-27b-3p Enhances Type I Interferon Expression and Suppresses
Infectious Bursal Disease Virus Replication via Targeting Cellular Suppressors
of Cytokine Signaling 3 and 6 (SOCS3 and 6). Virus Research 2020, Feb 29:197910. doi:
10.1016/j.virusres.2020.197910. PMID: 32126296
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Duan
X, Zhao M, Wang Y, Li X, Cao H, and Zheng SJ*. Epigenetic upregulation of chicken
microRNA-16-5p expression in DF-1 cells following infection with Infectious Bursal Disease
Virus (IBDV) enhances IBDV-induced
apoptosis and viral replication. J
Virology 2020, 94(2). pii: e01724-19. doi: 10.1128/JVI.01724-19
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Zhao
M, Duan X, Wang Y, Gao L, Cao H, Li X*, and Zheng SJ*. A novel role for PX, a
structural Protein of Fowl Adenovirus Serotype 4 (FAdV4), as an
Apoptosis-inducer in Leghorn Male Hepatocellular Cells. Viruses 2020, Feb 18;12(2). pii:
E228. doi: 10.3390/v12020228
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Zhou
L and Zheng SJ* The roles of microRNAs(miRNAs) in avian response to viral infection and pathogenesis of avian immunosuppressive diseases. Itnl J of Mol Sci 2019, Nov 1;20(21). pii: E5454. doi:
10.3390/ijms20215454
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Gao J, Zhao M, Duan X, Wang Y, Cao H, Li X* and Zheng SJ* Requirement of cellular protein CCT7
for the replication of fowl adenovirus serotype 4 (FAdV-4) in leghorn male
hepatocellular cells via interaction with the viral hexon protein. Viruses
2019, 11, 107; doi:10.3390/v11020107
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He Z, Chen X, Fu M, Tang J, Li X, Cao H, Wang Y*, and Zheng SJ*.Inhibition of fowl
adenovirus serotype 4 replication in Leghorn male hepatoma cells by SP600125
via blocking JNK MAPK pathway. Vet Microbiology 2019, 228: 45-52
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Gao J, Duan X, Li XQ, Cao H, Wang Y* and Zheng SJ* Emerging of A Highly Pathogenic and Multi-drug
resistant Strain of Escherichia Coli Causing an outbreak of Colibacillosis in
Chickens, Infection, Genetics and Evolution 2018, 65: 392-398
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Fu M, Wang B, Chen X, He Z, Wang Y, Li X, Cao H, Zheng SJ*. gga-miR-454 suppresses infectious bursal
disease virus (IBDV) replication via directly targeting IBDV genomic segment B
and cellular Suppressors of Cytokine Signaling 6 (SOCS6). Virus Research 2018,
252: 29-40
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Wang B, Fu M, Liu Y, Wang Y, Li X, Cao H, and Zheng SJ* gga-miR-155 Enhances Type I Interferon
Expression and Suppresses Infectious Burse Disease Virus Replication via
Targeting SOCS1 and TANK. Front Cell Infect Microbiol 2018, 8(55); 1-13
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Chen X, He Z, Fu M, Wang Y, Wu H, Li X, Cao H, and Zheng SJ* The E3 ubiquitin ligase Siah-1 suppresses
avian reovirus infection by targeting p10 for degradation, J Virology 2018,
92(6). pii: e02101-17
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Wang B, Duan X, Fu M, Liu Y, Wang Y, Li X, Cao H, and Zheng SJ* The Association of Ribosomal Protein L18
(RPL18) with IBDV VP3 Enhances Viral Replication, Virus Research 2018,
245:69-79
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He Z, Chen X, Fu M, Tang J, Li X, Cao H, Wang Y, and Zheng SJ*. Infectious bursal disease virus protein VP4
suppresses, type I interferon expression via inhibiting K48-linked
ubiquitylation of glucocorticoid-induced leucine zipper (GILZ), Immunobiology
2018, 223(4-5):374-382
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Fu M, Wang B, Chen X, He Z, Wang Y, Li X, Cao H, and Zheng SJ*, gga-miR-130b suppresses infectious bursal
disease virus replication via targeting the viral genome and cellular SOCS5,J
Virology 2017, 92(1). pii: e01646-17
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Qin Y, Xu Z, Wang Y, Li X, Cao H, and Zheng
SJ*, VP2 of Infectious Bursal Disease Virus induces apoptosis
via triggering Oral Cancer Overexpressed 1 (ORAOV1) protein degradation. Front
Microbiology 2017, July, 8(1): doi: 10.3389/fmicb.2017.01351
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Li X, Liu Y, Wang Y, Liu J, Li XQ, Cao H, Gao X and Zheng SJ*, Negative regulation of hepatic inflammation
by the Soluble Resistance-Related Calcium Binding Protein via STAT3. Front
Immunology 2017, 8: 1-14
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Qin Y and Zheng SJ* .Infectious Bursal Disease Virus-Host Interactions: Multifunctional Viral
Proteins that Perform Multiple and Differing Jobs. Itnl J of Mol Sci 2017, 18,
161; doi:10.3390/ijms18010161
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Xu Z, Qin Y, Wang Y, Li X,Cao H, and Zheng
SJ*, A Critical role of bacterioferritin in Salmonella
pullorum-induced IFN-β expression in DF-1 cells, Front Microbiology 2016,
7(1): doi: 10.3389/fmicb.2016.00020
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Wu H, H Z, Tang J, Li X,Cao H, Wang Y*, and Zheng SJ* A critical role of
LAMP-1 inavian reovirus P10 degradation associated with inhibition of apoptosis
and virus release. Arch Virol 2016, 161:899–911
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Lin W, Zhang Z, Xu Z, Wang B, Wang Y, Li XQ, Cao H, and Zheng SJ*. The Association
of Receptor of Activated Protein Kinase C 1(RACK1) with Infectious Bursal
Disease Virus Protein VP5 and VDAC2 Inhibits Apoptosis and Enhances Viral
Replication. J Biol Chem. 2015, 290(13): 8500-10
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Zhang Z, Lin W, Wu H, Wang Y, Li XQ, Cao H, and Zheng SJ*, Critical Roles of Eukaryotic Elongation
Factor 1 alpha(eEF1A1)in Avian Reovirus Sigma C-induced Apoptosis and
Inhibition of Viral Growth. Archives of Virology 2015, 160:1449–1461
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Zheng W, Li X, Wang J, Li XQ, Cao H, Wang Y, Zeng Q, and Zheng SJ*. A critical role
of interferon-induced protein IFP35 inFoot-and-Mouth Disease Virus(FMDV) protein2C-induced
type I interferon response in cells. Archives of Virology 2014, 159(11):2925-35
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Li X, Wang J, Liu J, Li Z, Wang Y, Xue Y, and Zheng SJ*. Engagement of Soluble Resistance-Related
Calcium Binding Protein (sorcin) with foot-and-mouth disease virus (FMDV) VP1
inhibits type I interferon response in cells, Vet Microbiology 2013,166: 35–46
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Li Z, Wang Y, Li X, Li XQ, Cao H, and Zheng
SJ*. Critical Roles of Glucocorticoid-Induced Leucine Zipper in
Infectious Bursal Disease Virus (IBDV)-induced Suppression of Type I Interferon
Expression and Enhancement of IBDV Growth in Host Cells via Interaction with
VP4. J Virology 2013, 87(2):1221-1231
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Li X, Li XQ, Cao H, Wang Y, and Zheng
SJ*. Engagement of new castle disease virus (NDV) matrix (M)
protein with charged multivesicular body protein (CHMP) 4 facilitates viral
replication. Virus Research 2013, 171: 80-88
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Wang J, Wang Y, Liu J, Ding L, Zhang Q, Li X, Cao H, Tang J, and Zheng SJ*. A critical role
of N-myc and STAT interactor (Nmi) in foot-and-mouth disease virus
(FMDV)2C-induced apoptosis. Virus Research 2012, 170 (2012) 59– 65
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Luo Z, Li Z, Chen K, Liu R, Li X, Cao H, and Zheng SJ*. Engagement of Heterogeneous Nuclear
Ribonucleoprotein M with Listeriolysin O Induces Type I Interferon Expression
and Restricts Listeria Monocytogenes Growth in Host Cells. Immunobiology 2012,
217(10): 972-981
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Li Z, Wang Y, Xue Y, Li X, Cao H, and Zheng
SJ*. A critical role for voltage-dependent anion channel (VDAC)2
ininfectious bursal disease virus (IBDV)-induced apoptosis in host cells via
interacting with VP5. J Virology 2012, 86(3): 1328-1338
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Ruan W, Wu Y, Zheng SJ*.
Different genetic patterns in avian Toll-like receptor (TLR)5 genes. Mol Biol
Rep. 2012,39(4)3419-26
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Ruan WK, Wu YH, An J, Cui DF, Li HR, Zheng
SJ*. Toll-like receptor 2 type 1 and type 2 polymorphisms in
different chicken breeds. Poultry Science. 2012, Jan; 91(1):101-6
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Ruan Q, Kameswaran V, Zhang Y, Zheng
S, Sun J, Wang J, Devirgiliis J, Liou HC, Beg AA, Chen YH. The Th17 immune
response is controlled by the Rel-ROR{gamma}-ROR{gamma}T transcriptional axis.
J Exp Med. 2011 Oct 24; 208 (11):2321-33
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Ruan WK, Zheng SJ*.
Polymorphisms of chicken toll-like receptor 1 type 1 and type2 indifferent
breeds. Poultry Science 2011, Sep; 90(9):1941-7
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Li H, Li X, Lu Y, Wang X, Zheng SJ*.
Staphylococcus sciuri exfoliative toxin C is a dimer that modulates macrophage
functions. Can. J. of Microbiology 2011, 57: 722-729
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Li H, Wang Y, Ding L, and Zheng SJ*.
Staphylococcus sciuri exfoliative toxin C (ExhC) is a necrosis-inducer for
mammalian cells. PLoS ONE 2011, 6 (7): e23145: 1-9
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Li H, He F, Zhang Z, Zheng SJ*.
Critical roles of amino acids Ser231, His107 and Asp156 of Staphylococcus
sciuri exfoliative toxin C (ExhC) in the induction of skin exfoliations of
neonate. Biologia 2011: 90-11C
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Chen K, Luo Z, Tang J, Zheng SJ*.
A critical role of heat shock cognate protein70 inApoptin-induced
phosphorylation of Akt. Biochem Biophys Res Commun. 2011 Jun 3; 409(2):200-4
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Chen K, Luo Z, Zheng SJ*.
Gallus Heat shock cognate protein 70, a novel binding partner of Apoptin. Virol
J. 2011 Jun 27; 8: 324-333
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付梦娇,王永强,李晓齐,曹红,陈福勇,郑世军*,一株传染性法氏囊病毒野毒株的分离与鉴定,亚洲兽医病例研究,2016,5(1), 5-10
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甘孟侯、郑世军《中国猪病学/甘孟侯、杨汉春主编》第九章:猪传染病的发生、发展及流行,123-133页,2005年8月,中国农业出版社
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甘孟侯、郑世军、李文刚《养鸡500天-第五版/甘孟侯主编》第八部分:疫病防治,121-231页,2007年1月,中国农业出版社
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郑世军(参编)《新编人兽共患病学》(金宁一等主编),1050-1082页,2007年9月,中国科技出版社
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郑世军参编《畜禽群发病防治》第三版(甘孟侯蒋金书主编)第一章:畜禽传染病流行规律和防控措施,3-18页,2009年10月,中国农业大学出版社
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郑世军参编《抗病毒天然免疫》(舒红兵主编),第一章:天然免疫简介,1-11页,2009年9月,科学出版社
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郑世军、宋清明主编《现代动物传染病学》郑世军撰写(1-13页;177-197页)、2013年12月,中国农业大学出版社(获国家出版基金项目资助)
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甘孟侯主编,郑世军、郎震美副主编《养鸡500天-第六版》第八部分:疫病防治,138-237页,2014年1月,中国农业出版社
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郑世军著《动物分子免疫学》2015年,2015年9月,中国农业大学出版社
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Zheng SJ, contributor to the IBDV chapter for the Book “Avian
Virology-Current Research and Future Trends” by Caister
Academic Press, Sept. 2019
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郑世军著《动物分子免疫学-第二版》2020年,2021年6月出版,中国农业大学出版社