基本情况

王国洪，美国美艾利尔免疫分析公司(Alere/Immunalysis Corp.)副总裁。

 

研究领域

免疫化学，有机合成化学，材料化学

 

教育背景

1992年至1995年 博士后，美国南加州大学

1987年至1990年 博士，中国科学院上海有机化学研究所

1984年至1987年 硕士，南开大学元素有机化学研究所

1980年至1984年 学士，徐州师范大学化学系

 

工作经历

2010 to present  Vice President of R&D, Alere/Immunalysis (note: Immunalysis was acquired by Alere in 2010)

2003- 2010  Vice President of R&D, Immunalysis Corp., Pomona, California 91767

1996-1997 and 1999 to 2012  Associate Director of R&D, Life Point, INC., Rancho Cucamonga, California 91730

1997-1998  Senior Research Scientist, Esterline TA MFG. 375 W. Arden Ave. Glendale, California 91209.

1995-1996  Research Scientist, West Los Angeles V.A.Medical Center, Los Angeles, California

1992-1995  Postdoctoral Research Associate, Loker Hydrocarbon Research Insititute(USC), Los Angeles, California

1990-1992  Assistant Professor, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

 

发明专利

  1. G. Wang and T. Foley, “Composition and Methods for Synthesis of Novel Tracers for Detecting Amphetamine and Methamphetamine in Body Fluids’, US 6, 472, 228 (2002)
  2. G. Wang, T. Foley, C. Chang and A. Avila, “ Novel Reagents for Detecting Tetrahydrocannabinoids”, US 6, 686, 209 (2004)


论文发表

  1. Kim HuynH, Sabine Whelan, Guohong Wang*, Phillip Tam, et al. “Development and validation of a new SEFRIATM Immunoassay for the detection of oxycodone in oral fluids”, SOFT, 2017, Boca Raton Florida
  2. Kim HuynH, Sabine Whelan, Guohong Wang*, Phillip Tam, et al. “Development and validation of a new SEFRIATM Immunoassay for the detection of PCP in oral fluids”, SOFT, 2017 Boca Raton, Florida
  3. Warren C. Rodrigues, Alexandra Adan, John and Guohong Wang, “Development of a highly sensitive oral fluid ELISA for the PINACA and related synthetic cannabinoids” SOFT, 2017 Boca Raton, Florida
  4. G. Wang, K. Huynh, R. Barhate, et al. “Development of a highly sensitive homogeneous immunoassay for the specific detection of methadone metabolites (EDDP) in urine, P-20, SOFT 2014, Grand Rapids, MI
  5. G. Wang, K. Huynh, R. Barhate, et al. “Development and validation of a highly sensitive homogeneous immunoassay for the detection of ketamine and its metabolites in urine”, P-28, SOFT 2014, Grand Rapids, MI
  6. W. Rodrigues, P. Catbagan, P. Tam and G. Wang, “Development a sensitive ELISA for the alcohol biomarker ethyl glucuronide io urine”, P-26, SOFT 2014, Grand Rapids, MI
  7. W. Rodrigues, P. Catabagan, S. Rana and G. Wang,”Detectiom of synthestic cannabiods in oral fluids using ELISA and LC-MS/MS”, J. Anal. Toxl. 2013, special issue p1-8
  8. G. Wang, K. Huynh, R. Barhate, et al. “Development and validation of a new homogeneous immunoassay for the detection of UR144 metabolites in urine” P 61, SOFT 2013, Orlando, FL
  9. W. Rodrigurs, P. Catabagan, G Wang, et al. “ Development and application of ELISA for thedetection of synthetic canabinoids in oral fluids”, P 126, SOFT 2013, Orlando, FL
  10. W. Rodriges, C. Castro, C. Catabagan and G. Wamg, “ Immunoassay screening of diphenhydramine in urine and blood using a newly developed assay”, J. Anal. Toxl. 2012, 123-129
  11. G. Wang*, K. Huynh, R. Barhate, et al. “Development of a homogeneous immunoassay for the detection of fentanyl in urine”, Forensic Science International 206(2011), p127-131
  12. G. Wang*, Kim Huynh, R. Barhate, et al. “Validation of a new homogeneous immunoassay for the detection of carisoprodol in urine”, J. Anal. Toxl. V25 (2011), P108
  13. G. Wang, M. Vincent and K. Huhyn, “The importantance of norbuprenorphine cross-reactivity in a buprenorphine urine assay”, SOFT 2010 at Richmont. USA
  14. G. Wang, W. Rodrigues, M. Vincent, et al,”Development and GCMS validation of a highly sensitive immunoassay of Buprenorphine and its major metabolites in urine’, J. Anal. Toxl. P377( (2007)
  15. X. Liu, X.He, C. Moor and G.Wang “Highly sensitive and specific liquid chromatography-tandem mass spectrometry method for testing ractopamine in cow and sheep urine”, J. Anal. Toxl. V33, P 289 (2009)
  16. W.Rodrigues, G Wang “ Development and GCMS Validation of ELISA and GCMS procedures for the Quantificatio of Dextromethorphan and its metabolite in Urine and Oral Fluid” J. Anal. Toxl. V32 (2008)
  17. K. Huhyn, G Wang and R. Barhate, et al “Development of  homogeneous immunoassay of zolpidem in urine”,. J. Anal. Toxl. P V33, P486(2009)
  18. G. Wang, M. Vincent, A, Agrawal and et al, “Qualitative Screening of Cocaine in Hair Using a Homogeneous Immunoassay Procedure”, P 23, SOFT, 2008, Phoenix, AZ
  19. G.Wang ,M.Vincent, A, Agrawal and et al, “Qualitative Screening of Amphetamines in Hair Using a Homogeneous Immunoassay Procedure”, P 24, SOFT, 2008, Phoenix, AZ
  20. G.Wang ,K. Huynh, W. Rodrigues and et al, “Development and Validation of a Highly Sensitive Homogeneous Immunoassay for the Detection of Delta-9-THC in Oral Fluid Collected with the Quantisal Device”, P 25, SOFT, 2008, Phoenix, AZ
  21. A. Agrawal, G.Wang ,M.Vincent, and et al, “Qualitative Screening of Opiates in Hair Using a Homogeneous Immunoassay Procedure”, P 26, SOFT, 2008, Phoenix, AZ
  22. A. Agrawal, G.Wang ,M.Vincent, and et al, “Qualitative Screening of Phencyclidine in Hair Using a Homogeneous Immunoassay Procedure”, P 27, SOFT, 2008, Phoenix, AZ
  23. W. Rodrigues, G. Wang, C. Moor and et al “ Monitoring Naltrexone Compliance in Urine by Enzyme Immunoassay and GC-MS”,P16, SOFT, 2008, Phoenix, AZ
  24. G. Wang, K. HuynH, R. Barhate, et al. “Validation of a new recombinant antibody fragment (rFab)-based homogeneous enzyme immunoassay for the highly specific detection of 60acetylmorphine in urine”, J. Anal. Toxi. 2005
  25. G. Wang and C. Yuan, “ A New Reaction of Phosphites with 2-Nitrostyrene Derivatives-----A Facile Route to N-Hydroxy-indo-3-phosphonates and Indo-2-one-3-phosphonates”, Heteroat. Chem. 1992, 3, 521
  26. C. Yuan and G. Wang, et al “Studies on Organophosphorus LXXVI: A Convenient Synthesis of 1-hydroxy-1-alkyl or 1-aryl-2-hydroxyaminophosphonic acids”, Phosphorus, Sulfur, Silicon, and Related Elem., 1992, 81, 149
  27. C. Yuan and G. Wang, “Studies on Organophosphorus Compound 64: A New Synthetic Approach to Phosphonopeptides with Phosphonamide Moiety”, Chinese Chem. Lett. 1992, 605
  28. C. Yuan, S. Cui, G. Wang, “Studies on Organophosphorus 53: A New Procedure for Synthesis of 1-Alkyl or 1-aryl-1-hydroxy-2-nitroethylphosphonates under PTC Conditions”, Synthesis, 1992, 258
  29. C. Yuan, G. Wang, “Studies on Organophosphorus Compounds 65: A Facile Synthetic Route to Phosphonopeptides”, Phosphorus, Sulfur and Silicon, 1992, 71, 207
  30. C. Yuan and G. Wang, “Studies on Organophosphorus Compounds 54: Synthesis of 1-hydroxy-1-alkyl(aryl)-2-aminoethylphosphonates and derivatives thereof”, Phosphorus, Sulfur and Silicon, 1991, 60, 90
  31. C. Yuan and S. Chen and G. Wang, “Studies on Organophosphorus Compounds 56: Acetyl Chloride------A Versatile Reagent for the Synthesis of 1-Aminoalkyl(aryl)phosphonic Acids Derivatives”, Synthesis, 1991, 490
  32. C. Yuan, S. Chen and G. Wang, “Mass Spectroscopic Studies of Protected 1-Aminophosponic Acids”, Phosphorus, Sulfur and Silicon, 1991, 60, 90
  33. C. Yuan and G. Wang, “Studies on Organophosphorus Compounds 52: A Facile and Direct Route to Dialkyl 1-N-(benzyloxycarbonylamino)-substituted Benzyl Phosphonates”, Synthesis, 1990, 522
  34. Y. Li and G. Wang, “A Novel One-pot Reaction of Addition, Reduction and Cyclization of 2-Nitrostyrene Derivatives with Dialkyl Phosphites in the Presence of Silylation Reagents”, Scientia Silica (B), 1988, 1137
  35. C. Yuan and G. Wang, “Studies on Organophosphorus Compounds 51: A Convenient Method For Preparation of Alkyl Hydrogen 1-N-(Benzyloxycarbonyl Amino)-Substituted Benzylphosphontes”, Synthesis, 1990, 256
  36. D. Zhang, Y. Li and G. Wang, “Nuclear Magnetic Resonance of Organophosphorus Compounds------1H, 13C and 31P NMR of Nitro (and Indo) phosphonates”, Chinese J. of Microwave and Radio-frequency Spectroscopy”, 1988, 107
  37. G. Wang and C. Yuan, “A New Method to Synthesis of 1-Aryl-2-nitroethylphosphonates”, Chemical J. of Chinese University, 1989, 373
  38. Y. Li and G. Wang, “ Synthesis and Properties of 2-Aminophosphonates”, The First National Conference on Organophosphorus Chemistry, CCS, Perking, 1989, 110
  39. H. Guo, G. Wang and W. P. Weber “Synthesis of High Molecular Weight Copolymer by Ru-catalyzed Step-Growth Copolymerization of Acetophenone and -Dienes”, Macromolecules, 1995, 28, 5686
  40. G. Wang, H. Guo and W. P. Weber, “Synthesis and Characterization of Novel Crown Ether Containing Copolymers: Ru-Catalyzed Copolymerization of 4’-Acetylbenzocrown Ethers with -Dienes”, Polymer Bull., 1996, 37, 169
  41. G. Wang ,  H. Guo and W. P. Weber, “Ru-Catalyzed Regioselective Step-Growth Copolymerization 3’4’-Methylenedioxyacetophenone and -Dienes”, J. Organometallic Chem. 1996, 521, 351
  42. H. Guo, G. Wang and W. P. Weber, “ Synthesis of High Molecular Weight Copolymers by Ru-Catalyzed Regioselective Step-growth Copolymerization of Acetophenone and -Dienes”, ACS Symposium Series 624: Advances in Step-growth Polymerization”, Ed by James L and Jeff Wong, American Chemical Society, Washington, DC, 1996, p99
  43. G. Wang and W. P. Weber, “Synthesis, Characterization and Platinum Catalyzed Hydrosilylation Crosslinking of Unsaturated Si-H Carbosilanes-Random 2:1:1 and 2:1:3 Copoly(methylsilylene/cis and trans-1,4-but-2-enylene/1,2-but-3-enylene). Physical Properties of Aliphatic Carbosilane Thermosets, Carbosilane/Carbon and Carbosilane/Glass Composites”, Chem. Mater. 1993, 1651
  44. H. Guo, G. Wang and W.  P. Weber, “Ruthenium Catalyzed Copolymerization of 2-Acetylphenantherene and -Dienes. Direct Synthesis of Copolymers with Regular Incorporated 2-Acetyl-1,3-phenantherene Units”, Polymer Bull. 1996, 37, 869
  45. H. Guo, G. Wang and W. P. Weber, “Chemical Modification of Copoly(methylsilene/1,4-phenylene by Pt catalyzed Hydrosilylation Reactions with Functionally Substituted Alkenes”, Inorganic and Organometallic Polymers, 1995, 5, 5000
  46. M. Tapsak, G. Wang and W. P. Weber, “Quantitative Determination of Completely Acelyted Pentaerythritol and Penteaerythritol Oligomers by High-performance Liquid Chromatography”, Anal. Chem. 1996, 68, 1685