ACRVM  >> Vol. 5 No. 2 (May 2017)

    急性心肌梗塞合并心功能不全的诊疗进展
    Diagnosis and Treatment Progress in Cardiac Insufficiency with Acute Myocardial Infarction

  • 全文下载: PDF(379KB) HTML   XML   PP.7-14   DOI: 10.12677/ACRVM.2017.52002  
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作者:  

刘 梅:安徽医科大学第三附属医院第一人民医院集团滨湖医院心内科,安徽 合肥

关键词:
综述急性心肌梗死心功能不全Overview Acute Myocardial Infarction Cardiac Insufficiency

摘要:

急性心肌梗塞常合并有急性心功能不全和(或)左室功能下降,对于心肌梗死后期的心功能不全发生率,短期及长期的致死率有显著影响。研究发现及时开通急性心肌梗死患者罪犯血管(溶栓或急诊PCI或溶栓后PCI,搭桥治疗),急性心肌梗死合并心功能不全发生率明显下降,仍有一部分急性心肌梗死患者合并有急性心功能不全及(或)左室功能不全,且这两种并发症常并存,互相影响,导致急性心肌梗死后“存活”患者的心功能不全的发生率增加。如何预防心肌梗死后急性心功能不全的发生,目前仍是临床关注的问题。下面就急性心肌梗塞合并心功能不全的流行病学,分型,机制等方面进行综述。

Acute myocardial infarction is often accompanied with acute cardiac inefficiency and/or left ventricular dysfunction that affects the incidence of cardiac insufficiency and short term and long-term mortality. The study found that the timely opening of blood vessels (thrombolysis or emergency PCI or thrombolysis after PCI, bypass treatment), in acute myocardial infarction pa-tients with acute myocardial infarction, remarkably reduce the acute cardiac inefficiency and/or left ventricular insufficiency, but there are still some patients with acute myocardial infarction have acute cardiac incomplete function and/or left ventricular dysfunction, these two complica-tions often coexist, and affect each other, leading to acute myocardial infarction “surviving” pa-tients increasing incidence of cardiac insufficiency. How to prevent the incidence of acute cardi-ac insufficiency in myocardial infarction patients which is focus in clinical. The overview is about the epidemiology, typing, and mechanisms of acute myocardial infarction with acute cardiac insufficiency.

文章引用:
刘梅. 急性心肌梗塞合并心功能不全的诊疗进展[J]. 亚洲心脑血管病例研究, 2017, 5(2): 7-14. https://doi.org/10.12677/ACRVM.2017.52002

参考文献

[1] Spencer, F.A., Meyer, T.E., Goldberg, R.J., et al. (1999) Twenty Year Trends (1975-1995) in the Incidence, In-Hos- pital and Long-Term Death Rates Associated with Heart Failure Complicating Acute Myocardial Infarction—A Community-Wide Perspective. Journal of the American College of Cardiology, 34, 1378-1387.
[2] Suter, L.G., Li, S.-X., Grady, J.N., et al. (2013) National Patterns of Risk-Standardized Mortality and Readmission after Hospitalization for Acute Myocardial Infarction. Heart Failure, and Pneumonia: Update on Publicly Reported Outcomes Measures Based on the 2013 Release. Journal of General Internal Medicine, 29, 1333-1340.
https://doi.org/10.1007/s11606-014-2862-5
[3] Spencer, F.A., Meyer, T.E., Gore, J.M. and Goldberg, R.J. (2002) Heterogeneity in the Management and Outcomes of Patients with Acute Myocardial Infarction Complicated by Heart Failure: The National Registry of Myocardial Infarction. Circulation, 105, 2605-2610.
https://doi.org/10.1161/01.CIR.0000017861.00991.2F
[4] Laura, P.A., Michela, D.R., Silvia, M., et al. (2010) Pro/Anti-Inflammatory Cytokine Imbalance in Post Ischemic Left Ventricular Remodeling. Mediators of Inflammation, 2010, Article ID: 974694.
https://doi.org/10.1155/2010/974694
[5] Wang, X., Lv, H., Gu, Y., et al. (2014) Protective Effect of Lycopene on Cardiac Function and Myocardial Fibrosis after Acute Myocardial Infarction in Rats via the Modulation of p38 and MMP-9. Journal of Molecular Histology, 45, 113-120.
https://doi.org/10.1007/s10735-013-9535-2
[6] Mohsen, M. and Shawky, A. (2015) The Diagnostic Utility of High-Sensitivity Cardiac Troponin T in Acute Coronary Syndrome. The Egyptian Heart Journal, 24, 1-9.
[7] Wang, J.A., Qin, Y., Lv, J., Tian, Y.F. and Dong, Y.J. (2015) Clinical Application of High-Sensitivity Cardiac Troponin T Test in Acute Myocardial Infarction Diagnosis. Genetics and Molecular Research, 14, 17959-17965.
https://doi.org/10.4238/2015.December.22.21
[8] 杜国有, 黄国强, 安辉, 等. 超敏肌钙蛋白I检测在急性冠状动脉综合征危险分层中的应用价值[J]. 国际检验医学杂志, 2014, 35(2), 182-183.
[9] Robert, T., Willemsen, A., Dinant, G.J. and Glatz, J.F.C. (2014) Heart-Type Fatty Acid Binding Protein (H-FABP) for the Early Evaluation of Suspected Acute Coronary. Biomarkers of Myocardial Cell Damage, 14, 1-31.
[10] Eurlings, L.W., Sanders-van Wilk, S., van Kraaij, D.J., et al. (2014) Risk Stratification with the Use of Serial N-Terminal Pro-B-Type Natriuretic Peptide Measurements during Admission and Early after Discharge in Heart Failure Patients: Post Hoc Analysis of the PRIMA Study. Journal of Cardiac Failure, 20, 881-890.
https://doi.org/10.1016/j.cardfail.2014.08.014
[11] Ribeiro, D.R.P., Ramos, A.M., Vieira, P.L., et al. (2014) High-Sensitivity C-Reactive Protein as a Predictor of Cardiovascular Events after ST-Elevation Myocardial Infarction. Arquivos Brasileiros de Cardiologia, 103, 69-75.
[12] Swiatkiewicz, I., Kozinski, M., Magielsk, P. et al. (2015) Value of C-Reactive Protein in Predicting Left Ventricular Remodelling in Patients with a First ST-Segment Elevation Myocardial Infarction. Circulation Research, 16, 368-384.
[13] Gururajan, P., Gurumurthy, P., Nayar, P., et al. (2012) Pregnancy Associated Plasma Protein-A (PAPP-A) as an Early Marker for the Diagnosis of Acute Coronary Syndrome. Indian Heart Journal, 64, 141-145.
https://doi.org/10.1016/s0019-4832(12)60049-2
[14] Khan, D.A., Sharif, M.S., et al. (2011) Diagnostic Performance of High-Sensitivity Troponin T, Myeloperoxidase, and Pregnancy-Associated Plasma Protein A Assays for Triage of Patients with Acute Myocardial Infarction. Korean Journal of Laboratory Medicine, 31, 172-178.
https://doi.org/10.3343/kjlm.2011.31.3.172
[15] Pascual-Figal, D.A., Manzano-Fernández, S., Boronat, M., et al. (2011) Soluble ST2, High-Sensitivity Troponin T- and N-Terminal Pro-B-type Natriuretic Peptide: Complementary Role for Risk Stratification in Acutely Decompensated Heart Failure. European Journal of Heart Failure, 13, 718-725.
https://doi.org/10.1093/eurjhf/hfr047
[16] Abdelmoneim, S.S., Martinez, M.W., et al. (2015) Resting Qualitative and Quantitative Myocardial Contrast Echocardiography to Predict Cardiac Events in Patients with Acute Myocardial Infarction and Percutaneous Revascularization. Heart and Vessels, 30, 45-55.
https://doi.org/10.1007/s00380-013-0460-9
[17] Souza, L.P., Campos, O., Peres, C.A., et al. (2011) Echocardiographic Predictors of Early In-Hospital Heart Failure during First ST-Elevation Acute Myocardial Infarction: Does Myocardial Performance Index and Left Atrial Volume Improve Diagnosis over Conventional Parameters of Left Ventricular Function? Cardiovascular Ultrasound, 9, 17.
https://doi.org/10.1186/1476-7120-9-17
[18] Westholm, C., Johnson, J., Sahlen, A., et al. (2013) Peak Systolic Velocity Using Color-Coded Tissue Doppler Imaging, a Strong and Independent Predictor of Outcome in Acute Coronary Syndrome Patients. Cardiovascular Ultrasound, 11, 19.
https://doi.org/10.1186/1476-7120-11-9
[19] Petrie, C.J., Voors, A.A., Robertson, M., et al. (2012) A Low Pulse Pressure Predicts Mortality in Subjects with Heart Failure after an Acute Myocardial Infarction: A Post-Hoc Analysis of the CAPRICORN Study. Clinical Research in Cardiology, 101, 29-35.
https://doi.org/10.1007/s00392-011-0360-x
[20] Shiraishi, J., Kohno, Y., Sawada, T., et al. (2013) Prognostic Impact of Pulse Pressure at Admission on In-Hospital Outcome after Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction. Heart and Vessels, 28, 434-441.
https://doi.org/10.1007/s00380-012-0277-y
[21] 邓长金, 彭娜, 成威, 等. 溶栓后PCI术与直接PCI术对急性心肌梗死患者近期心功能的影响[J]. 临床心血管病杂志, 2014, 30(9): 779-781.
[22] Wu, W., Huang, L., Zhang, J., et al. (2012) High-Frequency Ultrasound Evaluation of Effects of Early Treatment with Metoprolol on Myocardial Inflammatory Cytokine Expression in Rats with Acute Myocardial Infarction. Journal of Huazhong University of Science and Technology, 32, 774-778.
https://doi.org/10.1007/s11596-012-1033-3
[23] Pan, H.-Y., Zhu, J.-H., Gu, Y., et al. (2014) Comparative Effects of Recombinant Human Brain Natriuretic Peptide and Dobutamine on Acute Decompensated Heart Failure Patients with Different Blood BNP Levels. BMC Cardiovascular Disorders, 14, 31.
[24] Omerovic, E., Råmunddal, T., Albertsson, P., et al. (2010) Levosimendan Neither Improves nor Worsens Mortality in Patients with Cardiogenic Shock Due to ST-Elevation Myocardial Infarction. Vascular Health and Risk Management, 6, 657-663.
https://doi.org/10.2147/VHRM.S8856
[25] Polegato, B.F., Minicucci, M.F., et al. (2016) Association between Functional Variables and Heart Failure after Myocardial Infarction in Rats. Arquivos Brasileiros de Cardiologia, 106, 105-112.
[26] 宋艳东, 李志忠, 张京梅. CRRT对急性心肌梗死后心功能不全低血压状态患者疗效分析[J]. 中国血液净化杂志, 2013, 12(3): 130-133.
[27] Herdrich, B.J., Gorman, R.C. et al. (2010) Progenitor Cells for the Treatment of Acute Myocardial Infarction. Advances in Skin & Wound Care, 1, 519-525.
[28] Flynn, A., Chen, X., O’Connell, E. and O’Brien, T. (2012) A Comparison of the Efficacy of Transplantation of Bone Marrow-Derived Mesenchymal Stem Cells and Unrestricted Somatic Stem Cells on Outcome after Acute Myocardial Infarction. Stem Cell Research & Therapy, 3, 36.
https://doi.org/10.1186/scrt127
[29] Rodrigo, S.F., van Ramshorst, J., et al. (2013) Intramyocardial Injection of Autologous Bone Marrow-Derived ex Vivo Expanded Mesenchymal Stem Cells in Acute Myocardial Infarction Patients Is Feasible and Safe up to 5 Years of Follow-Up. Stem Cell Research & Therapy, 6, 816-825.
https://doi.org/10.1007/s12265-013-9507-7