[1]
|
Abdellatif, K.R.A. and Fadaly, W.A. (2017) Design, Synthesis, Cyclooxygenase Inhibition and Biological Evaluation of New 1,3,5-Triaryl-4,5-Dihydro-1H-Pyrazole Derivatives Possessing Amino/Methanesulfonyl Pharmacophore. Bioor-ganic Chemistry, 70, 57-66. https://doi.org/10.1016/j.bioorg.2016.11.008
|
[2]
|
Abdellatif, K.R.A., Abdelall, E.K.A., Lamie, P.F., Labib, M.B., El-Nahaas, E.S. and Abdelhakeem, M.M. (2020) New Pyrazole Derivatives Pos-sessing Amino/Methanesulphonyl Pharmacophore with Good Gastric Safety Profile: Design, Synthesis, Cyclooxygenase Inhibition, Anti-Inflammatory Activity and Histopathological Studies. Bioorganic Chemistry, 95, Article ID: 103540. https://doi.org/10.1016/j.bioorg.2019.103540
|
[3]
|
Abdel-Maksoud, M.S., El-Gamal, M.I., Gamal El-Din, M.M., Choi, Y., Choi, J., Shin, J.S., Kang, S.Y., Yoo, K.H., Lee, K.T., Baek, D. and Oh, C.H. (2018) Synthesis of New Tri-arylpyrazole Derivatives Possessing Terminal Sulfonamide Moiety and Their Inhibitory Effects on PGE2 and Nitric Ox-ide Productions in Lipopolysaccharide-Induced RAW 264.7 Macrophages. Molecules, 23, Article No. 2556. https://doi.org/10.3390/molecules23102556
|
[4]
|
El-Shoukrofy, M.S., Abd El Razik, H.A., AboulWafa, O.M., Bayad, A.E. and El-Ashmawy, I.M. (2019) Pyrazoles Containing Thiophene, Thienopyrimidine and Thienotriazolopy-rimidine as COX-2 Selective Inhibitors: Design, Synthesis, in Vivo Anti-Inflammatory Activity, Docking and in Silico Chemo-Informatic Studies. Bioorganic Chemistry, 85, 541-557. https://doi.org/10.1016/j.bioorg.2019.02.036
|
[5]
|
Farooq, M., Sharma, A., Almarhoon, Z., Al-Dhfyan, A., El-Faham, A., Taha, N.A., Wadaan, M.A.M., Torre, B.G. and Albericio, F. (2019) Design and Synthesis of Mono-and Di-Pyrazolyl-s-Triazine Derivatives, Their Anticancer Profile in Human Cancer Cell Lines, and in Vivo Toxicity in Zebrafish Embryos. Bioorganic Chemistry, 87, 457-464.
https://doi.org/10.1016/j.bioorg.2019.03.063
|
[6]
|
Florentino, I.F., Silva, D.P.B., Cardoso, C.S., Menegatti, R., de Carvalho, F.S., Liao, L.M., Pinto, P.M., Peigneur, S., Costa, E.A. and Tytgat, J. (2019) Antinociceptive Effects of New Pyrazoles Compounds Mediated by the ASIC-1α Channel, TRPV-1 and μMOR Receptors. Biomedicine & Pharma-cotherapy, 115, Article ID: 108915.
https://doi.org/10.1016/j.biopha.2019.108915
|
[7]
|
Oliveira, D.H., Sousa, F.S.S., Birmann, P.T., Alves, D., Jacob, R.G., Savegnago, L. (2020) Antinociceptive and Anti-Inflammatory Effects of 4-(Arylchalcogenyl)-1H-Pyrazoles Con-taining Selenium or Sulfur. Pharmacological Reports, 72, 36-46. https://doi.org/10.1007/s43440-019-00001-4
|
[8]
|
Pratik, K., Arun, K., Neha, S., Bhumika, Y., Anshuman, S. and Kumar, G.S. (2018) Synthesis, Characterization of Ethyl 5-(Substituted)-1H-Pyrazole-3-Carboxylate Derivative as Potent Anti-inflammatory Agents. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 17, 32-38. https://doi.org/10.2174/1871523017666180411155240
|
[9]
|
Taher, A.T., Mostafa Sarg, M.T., El-Sayed Ali, N.R. and Hilmy Elnagdi, N. (2019) Design, Synthesis, Modeling Studies and Biological Screening of Novel Pyrazole Deriva-tives as Potential Analgesic and Anti-Inflammatory Agents. Bioorganic Chemistry, 89, Article ID: 103023. https://doi.org/10.1016/j.bioorg.2019.103023
|
[10]
|
Yao, H., Guo, Q., Wang, M., Wang, R. and Xu, Z. (2021) Discovery of Pyrazole N-Aryl Sulfonate: A Novel and Highly Potent Cyclooxygenase-2 (COX-2) Selective Inhibitors. Bioorganic & Medicinal Chemistry, 46, Article ID: 116344. https://doi.org/10.1016/j.bmc.2021.116344
|
[11]
|
Knorr, L. (1883) Einwirkung von acetessigester auf phenylhydra-zin. European Journal of Inorganic Chemistry, 16, 2597-2599. https://doi.org/10.1002/cber.188301602194
|
[12]
|
Girish, Y.R., Kumar, K.S.S., Manasa, H.S. and Shashikanth, S. (2014) ZnO: An Ecofriendly, Green Nano-Catalyst for the Synthesis of Pyrazole Derivatives under Aqueous Media. Journal of the Chinese Chemical Society, 61, 1175-1179.
https://doi.org/10.1002/jccs.201400170
|
[13]
|
O’Shea, P., Gosselin, F., Webster, R., Reamer, R., Tillyer, R. and Grabowski, E. (2006) Highly Regioselective Synthesis of 1-Aryl-3,4,5-Substituted Pyrazoles. Synlett, 2006, 3267-3270. https://doi.org/10.1055/s-2006-956487
|
[14]
|
Bishop, B., Brands, K., Gibb, A. and Kennedy, D. (2003) Regioselec-tive Synthesis of 1,3,5-Substituted Pyrazoles from Acetylenic Ketones and Hydrazines. Synthesis, 2004, 43-52. https://doi.org/10.1055/s-2003-44376
|
[15]
|
Rao, V.K., Tiwari, R., Chhikara, B.S., Shirazi, A.N., Parang, K. and Kumar, A. (2013) Copper Triflate-Mediated Synthesis of 1,3,5-Triarylpyrazoles in [Bmim][PF6] Ionic Liquid and Evalu-ation of Their Anticancer Activities. RSC Advances, 3, 15396-15403. https://doi.org/10.1039/c3ra41830h
|
[16]
|
Kat-ritzky, A.R., Wang, M., Zhang, S., Voronkov, M.V. and Steel, P.J. (2001) Regioselective Synthesis of Polysubstituted Pyrazoles and Isoxazoles. The Journal of Organic Chemistry, 66, 6787-6791. https://doi.org/10.1021/jo0101407
|
[17]
|
He, S., Chen, L., Niu, Y.N., Wu, L.Y. and Liang, Y.M. (2009) 1,3-Dipolar Cycloaddition of Diazoacetate Compounds to Terminal Alkynes Promoted by Zn(OTf)2: An Efficient Way to the Preparation of Pyrazoles. Tetrahedron Letters, 50, 2443-2445. https://doi.org/10.1016/j.tetlet.2009.03.030
|
[18]
|
Gioiello, A., Khamidullina, A., Fulco, M.C., Venturoni, F., Zlot-sky, S. and Pellicciari, R. (2009) New One-Pot Synthesis of Pyrazole-5-Carboxylates by 1,3-Dipole Cycloadditions of Ethyl Diazoacetate with α-Methylene Carbonyl Compounds. Tetrahedron Letters, 50, 5978-5980. https://doi.org/10.1016/j.tetlet.2009.07.152
|
[19]
|
Delaunay, T., Genix, P., Es-Sayed, M., Vors, J.P., Monteiro, N. and Balme, G. (2010) A Modular Sydnone Cycloaddition/Suzuki-Miyaura Cross-Coupling Strategy to Unsymmetrical 3,5-Bis (Hetero) Aromatic Pyrazoles. Organic Letters, 12, 3328-3331. https://doi.org/10.1021/ol101087j
|
[20]
|
Oh, L.M. (2006) Synthesis of Celecoxib via 1,3-Dipolar Cycloaddition. Tetrahedron Letters, 47, 7943-7946.
https://doi.org/10.1016/j.tetlet.2006.08.138
|
[21]
|
Yadav, J.S., Reddy, B.V.S., Srinivas, M., Prabhakar, A. and Jagadeesh, B. (2004) Montmorillonite KSF Clay-Promoted Synthesis of Enantiomerically Pure 5-Substituted Pyrazoles from 2,3-Dihydro-4H-Pyran-4-Ones. Tetrahedron Letters, 45, 6033-6036. https://doi.org/10.1016/j.tetlet.2004.06.031
|
[22]
|
Xie, F., Cheng, G. and Hu, Y. (2006) Three-Component, One-Pot Reaction for the Combinatorial Synthesis of 1,3,4-Substituted Pyrazoles. Journal of Combinatorial Chemistry, 8, 286-288. https://doi.org/10.1021/cc050159d
|
[23]
|
Ilhan, I.Ö., Saripinar, E. and Akçamur, Y. (2005) Synthesis of Some Pyrazole-3-Carboxylic Acid Hydrazide and Pyrazolopyridazine Compounds. Journal of Heterocyclic Chemistry, 42, 117-120. https://doi.org/10.1002/jhet.5570420117
|
[24]
|
Krishnaiah, A. and Narsaiah, B. (2002) A Novel Ap-proach to the Synthesis of 5 Trifluoromethyl-3-Substituted Pyrazoles. Journal of Fluorine Chemistry, 115, 9-11. https://doi.org/10.1016/S0022-1139(01)00501-2
|
[25]
|
Liu, J.J., Zhang, H., Sun, J., Wang, Z.C., Yang, Y.S., Li, D.D., Zhang, F., Gong, H.B. and Zhu, H.L. (2012) Synthesis, Biological Evaluation of Novel 4,5-Dihydro-2H-Pyrazole 2-Hydroxyphenyl Derivatives as BRAF Inhibitors. Bioorganic & Medicinal Chemistry, 20, 6089-6096. https://doi.org/10.1016/j.bmc.2012.08.020
|
[26]
|
Sun, J., Lv, X.H., Qiu, H.Y., Wang, Y.T., Du, Q.R., Li, D.D., Yang, Y.H. and Zhu, H.L. (2013) Synthesis, Biological Evaluation and Molecular Docking Studies of Pyrazole Deriva-tives Coupling with a Thiourea Moiety as Novel CDKs Inhibitors. European Journal of Medicinal Chemistry, 68, 1-9. https://doi.org/10.1016/j.ejmech.2013.07.003
|
[27]
|
Xu, Y., Liu, X.H., Saunders, M., Pearce, S., Foulks, J.M., Par-nell, K.M., Clifford, A., Nix, R.N., Bullough, J., Hendrickson, T.F., Wright, K., McCullar, M.V., Kanner, S.B. and Ho, K.K. (2014) Discovery of 3-(Trifluoromethyl)- 1H-Pyrazole-5-Carboxamide Activators of the M2 Isoform of Pyruvate Kinase (PKM2). Bioorganic & Medicinal Chemistry, 24, 515-519. https://doi.org/10.1016/j.bmcl.2013.12.028
|
[28]
|
Li, X., Lu, X., Xing, M., Yang, X.H., Zhao, T.T., Gong, H.B. and Zhu, H.L. (2012) Synthesis, Biological Evaluation, and Molecular Docking Studies of N,1,3-Triphenyl-1H-Pyrazole-4-Carboxamide Derivatives as Anticancer Agents. Bioorganic & Medicinal Chemistry, 22, 3589-3593. https://doi.org/10.1016/j.bmcl.2012.04.066
|
[29]
|
Huang, Y.Y., Wang, L.Y., Chang, C.H., Kuo, Y.H., Kaneko, K., Takayama, H., Kimura, M., Juang, S.H. and Wong, F.F. (2012) One-Pot Synthesis and Antiproliferative Evaluation of Pyrazolo[3,4-d]Pyrimidine Derivatives. Tetrahedron, 68, 9658-9664. https://doi.org/10.1016/j.tet.2012.09.054
|
[30]
|
Abdellatif, K.R.A. and Fadaly, W.A. (2017) Design, Synthesis, Cyclooxygenase Inhibition and Biological Evaluation of New 1,3,5-Triaryl-4,5-Dihydro-1H-Pyrazole Derivatives Possessing Amino/Methanesulfonyl Pharmacophore. Bioor-ganic Chemistry, 70, 57-66. https://doi.org/10.1016/j.bioorg.2016.11.008
|
[31]
|
Abdellatif, K.R.A., Abdelall, E.K.A., Lamie, P.F., Labib, M.B., El-Nahaas, E.S. and Abdelhakeem, M.M. (2020) New Pyrazole Derivatives Pos-sessing Amino/Methanesulphonyl Pharmacophore with Good Gastric Safety Profile: Design, Synthesis, Cyclooxygenase Inhibition, Anti-Inflammatory Activity and Histopathological Studies. Bioorganic Chemistry, 95, Article ID: 103540. https://doi.org/10.1016/j.bioorg.2019.103540
|
[32]
|
Abdel-Maksoud, M.S., El-Gamal, M.I., Gamal El-Din, M.M., Choi, Y., Choi, J., Shin, J.S., Kang, S.Y., Yoo, K.H., Lee, K.T., Baek, D. and Oh, C.H. (2018) Synthesis of New Tri-arylpyrazole Derivatives Possessing Terminal Sulfonamide Moiety and Their Inhibitory Effects on PGE2 and Nitric Ox-ide Productions in Lipopolysaccharide-Induced RAW 264.7 Macrophages. Molecules, 23, Article No. 2556. https://doi.org/10.3390/molecules23102556
|
[33]
|
El-Shoukrofy, M.S., Abd El Razik, H.A., AboulWafa, O.M., Bayad, A.E. and El-Ashmawy, I.M. (2019) Pyrazoles Containing Thiophene, Thienopyrimidine and Thienotriazolopy-rimidine as COX-2 Selective Inhibitors: Design, Synthesis, in Vivo Anti-Inflammatory Activity, Docking and in Silico Chemo-Informatic Studies. Bioorganic Chemistry, 85, 541-557. https://doi.org/10.1016/j.bioorg.2019.02.036
|
[34]
|
Farooq, M., Sharma, A., Almarhoon, Z., Al-Dhfyan, A., El-Faham, A., Taha, N.A., Wadaan, M.A.M., Torre, B.G. and Albericio, F. (2019) Design and Synthesis of Mono-and Di-Pyrazolyl-s-Triazine Derivatives, Their Anticancer Profile in Human Cancer Cell Lines, and in Vivo Toxicity in Zebrafish Embryos. Bioorganic Chemistry, 87, 457-464.
https://doi.org/10.1016/j.bioorg.2019.03.063
|
[35]
|
Florentino, I.F., Silva, D.P.B., Cardoso, C.S., Menegatti, R., de Carvalho, F.S., Liao, L.M., Pinto, P.M., Peigneur, S., Costa, E.A. and Tytgat, J. (2019) Antinociceptive Effects of New Pyrazoles Compounds Mediated by the ASIC-1α Channel, TRPV-1 and μMOR Receptors. Biomedicine & Pharma-cotherapy, 115, Article ID: 108915.
https://doi.org/10.1016/j.biopha.2019.108915
|
[36]
|
Oliveira, D.H., Sousa, F.S.S., Birmann, P.T., Alves, D., Jacob, R.G., Savegnago, L. (2020) Antinociceptive and Anti-Inflammatory Effects of 4-(Arylchalcogenyl)-1H-Pyrazoles Con-taining Selenium or Sulfur. Pharmacological Reports, 72, 36-46. https://doi.org/10.1007/s43440-019-00001-4
|
[37]
|
Pratik, K., Arun, K., Neha, S., Bhumika, Y., Anshuman, S. and Kumar, G.S. (2018) Synthesis, Characterization of Ethyl 5-(Substituted)-1H-Pyrazole-3-Carboxylate Derivative as Potent Anti-inflammatory Agents. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 17, 32-38. https://doi.org/10.2174/1871523017666180411155240
|
[38]
|
Taher, A.T., Mostafa Sarg, M.T., El-Sayed Ali, N.R. and Hilmy Elnagdi, N. (2019) Design, Synthesis, Modeling Studies and Biological Screening of Novel Pyrazole Deriva-tives as Potential Analgesic and Anti-Inflammatory Agents. Bioorganic Chemistry, 89, Article ID: 103023. https://doi.org/10.1016/j.bioorg.2019.103023
|
[39]
|
Yao, H., Guo, Q., Wang, M., Wang, R. and Xu, Z. (2021) Discovery of Pyrazole N-Aryl Sulfonate: A Novel and Highly Potent Cyclooxygenase-2 (COX-2) Selective Inhibitors. Bioorganic & Medicinal Chemistry, 46, Article ID: 116344. https://doi.org/10.1016/j.bmc.2021.116344
|
[40]
|
Knorr, L. (1883) Einwirkung von acetessigester auf phenylhydra-zin. European Journal of Inorganic Chemistry, 16, 2597-2599. https://doi.org/10.1002/cber.188301602194
|
[41]
|
Girish, Y.R., Kumar, K.S.S., Manasa, H.S. and Shashikanth, S. (2014) ZnO: An Ecofriendly, Green Nano-Catalyst for the Synthesis of Pyrazole Derivatives under Aqueous Media. Journal of the Chinese Chemical Society, 61, 1175-1179.
https://doi.org/10.1002/jccs.201400170
|
[42]
|
O’Shea, P., Gosselin, F., Webster, R., Reamer, R., Tillyer, R. and Grabowski, E. (2006) Highly Regioselective Synthesis of 1-Aryl-3,4,5-Substituted Pyrazoles. Synlett, 2006, 3267-3270. https://doi.org/10.1055/s-2006-956487
|
[43]
|
Bishop, B., Brands, K., Gibb, A. and Kennedy, D. (2003) Regioselec-tive Synthesis of 1,3,5-Substituted Pyrazoles from Acetylenic Ketones and Hydrazines. Synthesis, 2004, 43-52. https://doi.org/10.1055/s-2003-44376
|
[44]
|
Rao, V.K., Tiwari, R., Chhikara, B.S., Shirazi, A.N., Parang, K. and Kumar, A. (2013) Copper Triflate-Mediated Synthesis of 1,3,5-Triarylpyrazoles in [Bmim][PF6] Ionic Liquid and Evalu-ation of Their Anticancer Activities. RSC Advances, 3, 15396-15403. https://doi.org/10.1039/c3ra41830h
|
[45]
|
Kat-ritzky, A.R., Wang, M., Zhang, S., Voronkov, M.V. and Steel, P.J. (2001) Regioselective Synthesis of Polysubstituted Pyrazoles and Isoxazoles. The Journal of Organic Chemistry, 66, 6787-6791. https://doi.org/10.1021/jo0101407
|
[46]
|
He, S., Chen, L., Niu, Y.N., Wu, L.Y. and Liang, Y.M. (2009) 1,3-Dipolar Cycloaddition of Diazoacetate Compounds to Terminal Alkynes Promoted by Zn(OTf)2: An Efficient Way to the Preparation of Pyrazoles. Tetrahedron Letters, 50, 2443-2445. https://doi.org/10.1016/j.tetlet.2009.03.030
|
[47]
|
Gioiello, A., Khamidullina, A., Fulco, M.C., Venturoni, F., Zlot-sky, S. and Pellicciari, R. (2009) New One-Pot Synthesis of Pyrazole-5-Carboxylates by 1,3-Dipole Cycloadditions of Ethyl Diazoacetate with α-Methylene Carbonyl Compounds. Tetrahedron Letters, 50, 5978-5980. https://doi.org/10.1016/j.tetlet.2009.07.152
|
[48]
|
Delaunay, T., Genix, P., Es-Sayed, M., Vors, J.P., Monteiro, N. and Balme, G. (2010) A Modular Sydnone Cycloaddition/Suzuki-Miyaura Cross-Coupling Strategy to Unsymmetrical 3,5-Bis (Hetero) Aromatic Pyrazoles. Organic Letters, 12, 3328-3331. https://doi.org/10.1021/ol101087j
|
[49]
|
Oh, L.M. (2006) Synthesis of Celecoxib via 1,3-Dipolar Cycloaddition. Tetrahedron Letters, 47, 7943-7946.
https://doi.org/10.1016/j.tetlet.2006.08.138
|
[50]
|
Yadav, J.S., Reddy, B.V.S., Srinivas, M., Prabhakar, A. and Jagadeesh, B. (2004) Montmorillonite KSF Clay-Promoted Synthesis of Enantiomerically Pure 5-Substituted Pyrazoles from 2,3-Dihydro-4H-Pyran-4-Ones. Tetrahedron Letters, 45, 6033-6036. https://doi.org/10.1016/j.tetlet.2004.06.031
|
[51]
|
Xie, F., Cheng, G. and Hu, Y. (2006) Three-Component, One-Pot Reaction for the Combinatorial Synthesis of 1,3,4-Substituted Pyrazoles. Journal of Combinatorial Chemistry, 8, 286-288. https://doi.org/10.1021/cc050159d
|
[52]
|
Ilhan, I.Ö., Saripinar, E. and Akçamur, Y. (2005) Synthesis of Some Pyrazole-3-Carboxylic Acid Hydrazide and Pyrazolopyridazine Compounds. Journal of Heterocyclic Chemistry, 42, 117-120. https://doi.org/10.1002/jhet.5570420117
|
[53]
|
Krishnaiah, A. and Narsaiah, B. (2002) A Novel Ap-proach to the Synthesis of 5 Trifluoromethyl-3-Substituted Pyrazoles. Journal of Fluorine Chemistry, 115, 9-11. https://doi.org/10.1016/S0022-1139(01)00501-2
|
[54]
|
Liu, J.J., Zhang, H., Sun, J., Wang, Z.C., Yang, Y.S., Li, D.D., Zhang, F., Gong, H.B. and Zhu, H.L. (2012) Synthesis, Biological Evaluation of Novel 4,5-Dihydro-2H-Pyrazole 2-Hydroxyphenyl Derivatives as BRAF Inhibitors. Bioorganic & Medicinal Chemistry, 20, 6089-6096. https://doi.org/10.1016/j.bmc.2012.08.020
|
[55]
|
Sun, J., Lv, X.H., Qiu, H.Y., Wang, Y.T., Du, Q.R., Li, D.D., Yang, Y.H. and Zhu, H.L. (2013) Synthesis, Biological Evaluation and Molecular Docking Studies of Pyrazole Deriva-tives Coupling with a Thiourea Moiety as Novel CDKs Inhibitors. European Journal of Medicinal Chemistry, 68, 1-9. https://doi.org/10.1016/j.ejmech.2013.07.003
|
[56]
|
Xu, Y., Liu, X.H., Saunders, M., Pearce, S., Foulks, J.M., Par-nell, K.M., Clifford, A., Nix, R.N., Bullough, J., Hendrickson, T.F., Wright, K., McCullar, M.V., Kanner, S.B. and Ho, K.K. (2014) Discovery of 3-(Trifluoromethyl)- 1H-Pyrazole-5-Carboxamide Activators of the M2 Isoform of Pyruvate Kinase (PKM2). Bioorganic & Medicinal Chemistry, 24, 515-519. https://doi.org/10.1016/j.bmcl.2013.12.028
|
[57]
|
Li, X., Lu, X., Xing, M., Yang, X.H., Zhao, T.T., Gong, H.B. and Zhu, H.L. (2012) Synthesis, Biological Evaluation, and Molecular Docking Studies of N,1,3-Triphenyl-1H-Pyrazole-4-Carboxamide Derivatives as Anticancer Agents. Bioorganic & Medicinal Chemistry, 22, 3589-3593. https://doi.org/10.1016/j.bmcl.2012.04.066
|
[58]
|
Huang, Y.Y., Wang, L.Y., Chang, C.H., Kuo, Y.H., Kaneko, K., Takayama, H., Kimura, M., Juang, S.H. and Wong, F.F. (2012) One-Pot Synthesis and Antiproliferative Evaluation of Pyrazolo[3,4-d]Pyrimidine Derivatives. Tetrahedron, 68, 9658-9664. https://doi.org/10.1016/j.tet.2012.09.054
|
[59]
|
Abdellatif, K.R.A. and Fadaly, W.A. (2017) Design, Synthesis, Cyclooxygenase Inhibition and Biological Evaluation of New 1,3,5-Triaryl-4,5-Dihydro-1H-Pyrazole Derivatives Possessing Amino/Methanesulfonyl Pharmacophore. Bioor-ganic Chemistry, 70, 57-66. https://doi.org/10.1016/j.bioorg.2016.11.008
|
[60]
|
Abdellatif, K.R.A., Abdelall, E.K.A., Lamie, P.F., Labib, M.B., El-Nahaas, E.S. and Abdelhakeem, M.M. (2020) New Pyrazole Derivatives Pos-sessing Amino/Methanesulphonyl Pharmacophore with Good Gastric Safety Profile: Design, Synthesis, Cyclooxygenase Inhibition, Anti-Inflammatory Activity and Histopathological Studies. Bioorganic Chemistry, 95, Article ID: 103540. https://doi.org/10.1016/j.bioorg.2019.103540
|
[61]
|
Abdel-Maksoud, M.S., El-Gamal, M.I., Gamal El-Din, M.M., Choi, Y., Choi, J., Shin, J.S., Kang, S.Y., Yoo, K.H., Lee, K.T., Baek, D. and Oh, C.H. (2018) Synthesis of New Tri-arylpyrazole Derivatives Possessing Terminal Sulfonamide Moiety and Their Inhibitory Effects on PGE2 and Nitric Ox-ide Productions in Lipopolysaccharide-Induced RAW 264.7 Macrophages. Molecules, 23, Article No. 2556. https://doi.org/10.3390/molecules23102556
|
[62]
|
El-Shoukrofy, M.S., Abd El Razik, H.A., AboulWafa, O.M., Bayad, A.E. and El-Ashmawy, I.M. (2019) Pyrazoles Containing Thiophene, Thienopyrimidine and Thienotriazolopy-rimidine as COX-2 Selective Inhibitors: Design, Synthesis, in Vivo Anti-Inflammatory Activity, Docking and in Silico Chemo-Informatic Studies. Bioorganic Chemistry, 85, 541-557. https://doi.org/10.1016/j.bioorg.2019.02.036
|
[63]
|
Farooq, M., Sharma, A., Almarhoon, Z., Al-Dhfyan, A., El-Faham, A., Taha, N.A., Wadaan, M.A.M., Torre, B.G. and Albericio, F. (2019) Design and Synthesis of Mono-and Di-Pyrazolyl-s-Triazine Derivatives, Their Anticancer Profile in Human Cancer Cell Lines, and in Vivo Toxicity in Zebrafish Embryos. Bioorganic Chemistry, 87, 457-464.
https://doi.org/10.1016/j.bioorg.2019.03.063
|
[64]
|
Florentino, I.F., Silva, D.P.B., Cardoso, C.S., Menegatti, R., de Carvalho, F.S., Liao, L.M., Pinto, P.M., Peigneur, S., Costa, E.A. and Tytgat, J. (2019) Antinociceptive Effects of New Pyrazoles Compounds Mediated by the ASIC-1α Channel, TRPV-1 and μMOR Receptors. Biomedicine & Pharma-cotherapy, 115, Article ID: 108915.
https://doi.org/10.1016/j.biopha.2019.108915
|
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