土拉弗朗西斯菌的研究现况
Current Status of Research on Francisella tularensis
DOI: 10.12677/AMB.2019.83016, PDF,  被引量    国家自然科学基金支持
作者: 苏 超：大理大学公共卫生学院，云南 大理；云南省地方病防治所/云南省自然疫源性疾病防控技术重点实验室/云南省鼠疫防治研究中心/徐建国院士工作站，云南 大理；吴鹤松, 杨桂荣：云南省地方病防治所/云南省自然疫源性疾病防控技术重点实验室/云南省鼠疫防治研究中心/徐建国院士工作站，云南 大理；宋志忠*：云南省疾病预防控制中心，云南 昆明
关键词: 土拉热；土拉弗朗西斯菌；研究现况；综述；Tularemia； Francisella tularensis； Research Status； Review
摘要: 土拉热，是由土拉弗朗西斯菌引起的一种人兽共患病。该病最早于1919年由E. Francis在美国的土拉县发现，因此被命名为土拉热。我国在1959年的黑龙江省报道了第一起人间感染。因其致病性强、易于传播的特点，被美国CDC列为A类生物恐怖病原体，因此对本病的深入研究具有重要的现实意义。本文从土拉弗氏菌的发现史、病原学特征、致病及传播机制、常见检测方法、疾病的诊断、临床表现及治疗、疫苗研究等几个方面进行了综述。
Abstract: Tularemia is a zoonotic disease caused by Francisella tularensis. The disease was first discovered in 1919 by E. Francis in Tulla County in the United States, so it was named Tularemia. In 1959, our country reported the first human infections in Heilongjiang province. Due to its characteristics of high pathogenicity and easy transmission, it is regarded as a class A bioterrorism pathogen by the CDC of the United States. Therefore, the in-depth study of this disease has important practical significance. In this paper, we reviewed the discovery history, pathogenic characteristics, pathogenic and transmission mechanism, common detection methods, disease diagnosis, clinical manifestations and treatment, vaccine research, etc.
文章引用：苏超, 吴鹤松, 杨桂荣, 宋志忠. 土拉弗朗西斯菌的研究现况[J]. 微生物前沿, 2019, 8(3): 130-138. https://doi.org/10.12677/AMB.2019.83016

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