基本情况
王久存,博士生导师,复旦大学生命科学学院教授,复旦大学风湿、免疫、过敏性疾病研究中心副主任,现代人类学教育部重点实验室科研主管,硬皮病临床与研究国际协作网(InSCAR)执行委员,上海市免疫学会风湿免疫专业委员会委员。
主要经历
2000年至今 复旦大学生命科学学院讲师、副教授、教授
2007年至2008年 美国德克萨斯大学休斯顿健康科学中心访问研究
1999年 获日本福井大学生物应用化学专业博士学位
1991年至1994年 任复旦大学生命科学学院助教、讲师
1988年和1991年,分获复旦大学生物系学士及硕士学位
研究领域
硬皮病、痛风、强直性脊柱炎等风湿、免疫性疾病的分子流行病学研究及分子致病机理研究;肺癌等肿瘤致病机理的遗传学及表观遗传学研究
论文发表(部分):
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Wang J, Yang Y, Guo S, Chen Y, Yang C, Ji H, Song X, Zhang F,
Jiang Z, Ma Y, Du R, Jin L, Reveille JD, Zou H, Zhou X. Association between
Copy Number Variations HLA-DQA1 and Ankylosing Spondylitis in Chinese Han
population. Genes and Immunity. Accepted
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Wang X, Wang L, Guo S, Bao Y, Ma Y, Yan F, Xu K, Xu Z,
Jin L, Lu D, Xu J, Wang JC*. Hypermethylation reduces expression of
tumor-suppressor PLZF and regulates proliferation and apoptosis in non-small
cell lung cancers. FASEB J. 2013 Jun 26. [Epub ahead of
print]
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Zhou XD*, Yi L, Guo XJ, Chen E, Zou HJ, Jin L, Mayes MD,
Assassi S, Wang JC*. Association of HLA-DQB1*0501 with scleroderma
and its clinical features in Chinese population. Int J Immunopath
Ph. 2003, Accepted
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Wang YL, Feng SH, Guo SC, Wei WJ, Li DS, Wang Y, Wang XF,
Wang ZY, Ma YY, Jin L, Ji QH*, Wang JC*. Confirmation of papillary
thyroid cancer susceptibility loci identified by genome-wide association
studies of chromosomes 14q13, 9q22, 2q35 and 8p12 in a Chinese population. J
Med Genet. 2013 Jul 11. [Epub ahead of print]
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Xu X; Wu WY; Tu WZ; Chu HY; Zhu XX; Liang MR; Xue
Y; Wang JC*; Zou HJ*. Increased Expression of S100A8
and S100A9 in Patients with diffuse cutaneous Systemic Sclerosis. A Correlation
with Organ Involvement and Immunological Abnormalities. Clin
Rheumatol. 2013 Jun 11. [Epub ahead of print]
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Zhang YH, Xu Q*, Zhao Z, Wu J, Liu WX, Wang H, Jin
L, Wang JC*. Polymorphism rs7214723 in CAMKK1 and lung cancer risk
in Chinese population. Tumour Biol. 2013 Jun 5. [Epub ahead
of print]
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Yi L#, Wang JC#, Guo
XJ, Gu YH, Tu WZ, Guo G, Yang L, Xiao R, Yu L, Mayes MD, Assassi S, Jin L, Zou
HJ and Zhou XD. STAT4 Is a Genetic Risk Factor for Systemic Sclerosis in
Chinese population. Int J Immunopath Ph. 2013;26(2):473-8
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Zhou X, Wang J, Zou H, Ward MM, Weisman MH,
Espitia1 MG, Xiao X, Petersdorf E, Mignot E, Martin J, Scheet P, Reveille JD.
MICA, A Gene Contributing Strong Susceptibility to Ankylosing
Spondylitis. Ann Rheum Dis. 2013;0:1–6
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Lin S, Pan L, Guo S, Wu J, Jin L, Wang JC*,
Wang S*. Prognostic Role of MicroRNA-181a/b in Hematological Malignancies: A
Meta-Analysis. PLoS ONE 2013;8(3):e59532
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Wei WJ, Wang YL, Li DS, Wang Y, Wang XF, Zhu YX, Yang YJ,
Wang ZY, Ma YY, Wu Y, Jin L, Ji QH, Wang JC*. Association between
the rs2910164 Polymorphism in Pre-Mir-146a Sequence and Thyroid
Carcinogenesis. PLoS ONE. 2013; 8(2):e56638