基本情况

吴伟，1992年和1996年毕业于第二军医大学药学院，分别获理学学士和医学硕士学位；1999年毕业于华西医科大学药剂学专业，获理学博士学位。2000年进入复旦大学药学院任教，现为药剂学教研室教授、博导。2007年至2012年曾任科研副院长。兼任：SFDA新药审评专家；国家药品价格审评专家；中国药学会药剂专业委员会委员；中华中医药学会制剂分会常委、中成药分会常委；中国颗粒学会生物颗粒专委会委员；上海药学会制药工程专委会委员、药剂专委会委员；《中国医药工业杂志》、Arch Pharm Res, Asian J Pharm Sci, JChin Pharm Sci, Nanomed Nanobiol等十余本期刊编委。主要从事药剂学的教学和科研工作，主要研究方向为微粒和纳米给药系统、口服给药系统、天然药物新型给药系统。主编《现代中药研究与开发》，参编十一五、十二五全国规划教材《药剂学》、《生物药剂学与药物动力学》等。主持国家及省部级研究课题10余项，授权专利5项，开发新药10余项，发表论文130余篇，其中SCI论文60余篇。曾获中国药学会－石药集团青年药剂学奖、上海市优秀教学成果二等奖、上海药学科技三等奖、军队科技进步三等奖等。教育部新世纪优秀人才、上海市曙光学者、上海高校优秀青年教师。

 

研究领域

微粒和纳米给药系统、口服给药系统、天然药物新型给药系统

 

论文发表

1. Mengmeng Niu, Ya’nan Tan, Peipei Guan, Lars Hovgaard, Yi Lu, Jianping Qi, Ruyue Lian, Xiaoyang Li, Wei Wu*. Enhanced oral absorption of insulin-loaded liposomes containing bile salts: a mechanistic study. Int J Pharm 2014, 460: 119-130
2. Xingwang Zhang, Jianping Qi, Yi Lu, Xiaoyang Li, Wei He, Wei Wu*. Biotinylated liposomes as potential carriers for oral delivery of insulin. Nanomedicine: Nanotech Biol Med 2014, 10: 167-176
3. Bei Zhang, Jian Chen, Yi Lu, Jianping Qi, Wei Wu*. Liposomes interiorlythickened with thermosensitive nanogelas novel drug delivery systems. Int J Pharm 2013, 455: 276-284
4. Wei He, Yi Lu, Jianping Qi, Lingyun Chen, Lifang Yin, Wei Wu*. Formulating food protein-stabilized indomethacinnanosuspensionsinto pellets by fluid-bed coating technology: Physical characterization, redispersibility and dissolution. Int J Nanomedicine 2013, 8: 3119-3128
5. Zhiqiang Tian, Jianping Qi*, Yueneng Yi, Jin Han, Hailong Yuan, Xi Zhang, Yunchang Xie, Fuqiang Hu, Yi Lu, Wei Wu*. Solidification of nanostructured lipid carrier (NLC) onto pellets by fluid-bed coating: preparation, in vitro characterization and bioavailability in dogs. Powd Tech 2013, 247: 120-7
6. Xi Zhang, Yueneng Yi, Jianping Qi, Yi Lu, Zhiqiang Tian, Yunchang Xie, Fuqiang Hu, Hailong Yuan, Wei Wu*. Controlled release of self-nanoemulsifying systems fromosmotic pump tablets: near zero-order release in vitro and pharmacokinetics in dogs. Int J Pharm2013, 452: 233-240
7. Wei He, Yi Lu, Jianping Qi, Lingyun Chen, Fuqiang Hu,Wei Wu*. Nanoemulsion-templated shell-crosslinked nanocapsules as drug delivery systems. Int J Pharm 2013, 445: 69-78
8. Yunchang Xie, Yi Lu, Jianping Qi, Xiaoyang Li, Xi Zhang, Jin Han, Shixiao Jin, Hailong Yuan*, Wei Wu*. Synchronized and controlledrelease of multiple components in silymarin achieved by the osmotic release strategy. Int J Pharm2013, 441: 111-120
9. Wei He, Yi Lu, Jianping Qi, Lingyun Chen, Fuqiang Hu, Wei Wu*. Food proteins as novel nanosuspension stabilizers for poorly water-soluble drugs. Int J Pharm2013, 441: 269-278
10. Shunwen Hu, Mengmeng Niu,Fuqiang Hu, Yi Lu, Jianping Qi, Zongning Yin*, Wei Wu*. Integrity and stability of oral liposomes containing bile salts studied in simulated and ex vivo gastrointestinal media. Int J Pharm2013, 441: 693-700
11. Xiaoyang Li, Jianping Qi*, Yunchang Xie, Xi Zhang, Shunwen Hu, Ying Xu, Yi Lu, Wei Wu*. Nanoemulsions coated with alginate/chitosan as oral insulin delivery systems: Preparation, characterization and hypoglycemic effect in rats. Int J Nanomedicine2013, 8: 23-32
12. Yi Lu, Tao Guo, Jian-ping Qi, Ji-wen Zhang*, Wei Wu*. Enhanced dissolution and stability of lansoprazole by cyclodextrin inclusion complexation: Preparation, characterization and molecular modeling. AAPS PharmSciTech2012, 13(4): 1222-1229
13. Ying Xu, Xiaoyi Liu, Ruyue Lian, Siyi Zheng, Zongning Yin, Yi Lu*, Wei Wu*. Enhanced dissolution and oral bioavailability ofaripiprazole nanosuspensionsprepared by nanoprecipitation/homogenizationbased on acid-base neutralization. Int J Pharm 2012, 438: 287-295
14. Shixiao Jin, Shanshan Fu, Jin Han, Shiying Jin, Qingyuan Lv, Yi Lu, Jianping Qi,Wei Wu*, Hailong Yuan*. Improvement of oral bioavailability of glycyrrhizin bysodium deoxycholate/phospholipid-mixed nanomicelles. J Drug Target, 2012, 20 (7): 615–622
15. Mengmeng Niu, Yi Lu, Lars Hovgaard, Peipei Guan, Yanan Tan, Ruyue Lian, Jianping Qi, Wei Wu*. Hypoglycemic activity and oral bioavailability of insulin-loaded liposomes containing bile salts in rats: the effect of cholate type, particle size and administered dose. Eur J Pharm Biopharm2012 81(2): 265-72
16. Yi Lu, Jianping Qi, Peipei Guan, Yuzhang Hu, Keping Ruan, Wei Wu*. Micronization of solid dispersion pellets: physical characterization and improved dissolution. Adv Sci Lett 2012(6): 200-206(7)