腹膜透析和血液透析对急性肾损伤的疗效对比

Comparison of Therapeutic Effects of Peritoneal Dialysis and Hemodialysis on Acute Renal Injury

摘要: 目的：对比血液透析和腹膜透析对急性肾损伤(AKI)的疗效。方法：选取2021年1月至2023年1月于陕西省人民医院开始透析的急性肾损伤(AKI)患者，共收集31例，其中血液透析(HD)组患者18例，腹膜透析(PD)组患者13例，两组患者年龄和性别差异无统计学意义(P > 0.05)，收集所有患者透析前和透析后的资料。结果：透析前收缩压、舒张压、体重指数、血钙、血磷、血钾、血钠、尿酸、白蛋白(ALB)、血红蛋白(HB)、视黄醇结合蛋白(RBP)、胱抑素-C (Cys-C)、中性粒细胞明胶酶相关脂质运载蛋白(NGAL)、补体C1q、二氧化碳结合力(ECO₂)水平两组之间均无统计学差异(P > 0.05)，而血糖、尿素(UREA)和肌酐(Scr)水平两组之间有统计学意义(P < 0.05)。透析治疗后，上述各项指标均有所改善，其中血肌酐，尿素，尿酸，Cys-C，NGAL，血钠，血磷下降，差异有统计学意义(P < 0.05) [HD与PD的比较结果]。结论：在AKI临床治疗上，腹膜透析相比于血液透析各有优劣，要根据患者的实际个人情况选择合理的透析方案，以期延长生存期，减少并发症发生。

Abstract: Objective: To compare the efficacy of haemodialysis and peritoneal dialysis on acute kidney injury (AKI). Methods: Acute kidney injury (AKI) patients who started dialysis in Shaanxi Provincial Peo-ple’s Hospital from January 2021 to January 2023 were selected, and a total of 31 cases were col-lected, among which 18 patients were in haemodialysis (HD) group, and 13 patients were in perito-neal dialysis (PD) group, and there was no statistical significance in the difference between the age and gender of patients in the two groups (P > 0.05), and the data of all the patients in the pre-dialysis and post-dialysis periods were collected. Results: There were no statistically significant differences in the pre-dialysis systolic blood pressure (BP), diastolic BP, body mass index (BMI), blood calcium, blood phosphorus, blood potassium, blood sodium, uric acid, albumin (ALB), haemo-globin (HB), retinol-binding protein (RBP), cystatin-C (Cys-C), neutrophil gelatinase-associated lipid transport protein (NGAL), complement C1q, and carbon dioxide binding (ECO₂) between the two groups (P > 0.05).It is statistically different (P > 0.05), while blood glucose, urea (UREA) and creati-nine (Scr) levels were statistically significant between the two groups (P < 0.05). After dialysis treatment, all of the above indicators improved, including blood creatinine, urea, uric acid, Cys-C, NGAL, blood sodium, blood phosphorus decreased, the difference was statistically significant (P < 0.05) [Comparison of HD and PD]. Conclusion; In the clinical treatment of AKI, peritoneal dialysis has its own advantages and disadvantages compared with haemodialysis, and a reasonable dialysis plan should be selected according to the actual personal situation of the patient, with a view to pro-longing survival and reducing complications.