中药复方改善急性痛风性关节炎症状和功能的研究进展

Research Progress on Improving Symptoms and Function of Acute Gouty Arthritis with Chinese Herbal Compound

摘要: 随着现代生活方式的改变，急性痛风性关节炎(acute gouty arthritis, AGA)的年轻化趋势日益凸显，必须引起足够的重视。AGA作为炎症性关节炎之一，不仅会引起患者关节红肿热痛，活动受限，除此之外，AGA反复发作还可以造成关节损害和残疾，甚至肾脏功能的损害，最终导致尿毒症。常规西药治疗虽见效快，但同时也存在着胃肠道及肝肾功能损害、骨髓抑制等不良反应，停药后易复发，因此中医药治疗AGA成为研究热点，中药复方治疗AGA不仅疗效安全，能够快速缓解急性期关节肿痛症状，还可以改善关节活动度，减轻关节功能障碍，减少复发率，值得临床广泛应用。

Abstract: With the change of modern lifestyle, the trend of young age of acute gouty arthritis has become in-creasingly prominent, and enough attention must be paid to it. As one of inflammatory arthritis, AGA will not only cause redness, swelling, heat and pain in patients’ joints, but also limit their activ-ities. In addition, repeated attacks of AGA can also cause joint damage and disability, even damage to renal function, and eventually lead to uremia. Although the conventional Western medicine treatment has a quick effect, it also has adverse reactions such as gastrointestinal tract, liver and renal function damage, bone marrow suppression, etc., which are easy to recur after drug with-drawal. Therefore, the treatment of AGA by traditional Chinese medicine has become a research hotspot. Chinese herbal compound is not only effective and safe, and can quickly alleviate the symptoms of acute stage pain and swelling, but also can improve joint mobility, reduce joint dys-function, and reduce the recurrence rate. It is worth extensive clinical application.