实性型甲状腺乳头状癌一例
Solid Papillary Thyroid Carcinoma: A Case Report
DOI: 10.12677/ACM.2024.141064, PDF,   
作者: 吴淑婷, 冉建民*:暨南大学附属广州红十字会医院内分泌科,广东 广州
关键词: 甲状腺乳头状癌桥本氏甲状腺炎临床病理Papillary Thyroid Carcinoma Hashimoto’s Thyroiditis Clinical Pathology
摘要: 甲状腺肿瘤病理分型复杂多样,不同病理类型之间存在重叠的细胞形态特征,术前诊断及鉴别难度较大,当合并桥本氏甲状腺炎时使诊断更加困难。本例青年男性,行超声检查发现桥本氏甲状腺炎、甲状腺结节,结节细针抽吸活检结果提示Bethesda III类,免疫组织化学染色CK19、TTF-1阳性,术后病理证实为实性型甲状腺乳头状癌,定期随访。
Abstract: Thyroid cancer pathology is complex and has duplicated cellular structures. Preoperative identifi-cation is difficult. When combined with Hashimoto’s thyroiditis, the diagnosis is even more complex. In this article, a man was found to have a thyroid nodule by ultrasonography, and the FNA suggest-ed Bethesdaclass III. immunohistochemical staining was positive for CK19 and TTF-1. After surgery, the pathology was solid papillary thyroid carcinoma. The follow-up was stable.
文章引用:吴淑婷, 冉建民. 实性型甲状腺乳头状癌一例[J]. 临床医学进展, 2024, 14(1): 447-450. https://doi.org/10.12677/ACM.2024.141064

参考文献

[1] Zhai, M., Zhang, D., Long, J., et al. (2021) The Global Burden of Thyroid Cancer and Its Attributable Risk Factor in 195 Countries and Territories: A Systematic Analysis for the Global Burden of Disease Study. Cancer Medicine, 10, 4542-4554. [Google Scholar] [CrossRef] [PubMed]
[2] Christofer, J.C., Mete, O. and Baloch, Z.W. (2023) The 2022 WHO Classification of Thyroid Tumors: Novel Concepts in Nomenclature and Grading. Endocrine-Related Cancer, 30, e220293. [Google Scholar] [CrossRef
[3] Carcangiu, M.L., Zampi, G., Pupi, A., et al. (1985) Papillary Carcinoma of the Thyroid. A Clinicopathologic Study of 241 Cases Treated at the University of Florence, Italy. Cancer, 55, 805-828. [Google Scholar] [CrossRef
[4] Williams, E.D., Abrosimov, A., Bogdanova, T., et al. (2004) Thyroid Carcinoma after Chernobyl Latent Period, Morphology and Aggressiveness. British Journal of Cancer, 90, 2219-2224. [Google Scholar] [CrossRef] [PubMed]
[5] Ohashi, R., Murase, Y., Matsubara, M., et al. (2017) Fine Needle Aspiration Cytology of the Papillary Thyroid Carcinoma with a Solid Component: A Cytological and Clinical Correlation. Diagnostic Cytopathology, 45, 391-398. [Google Scholar] [CrossRef] [PubMed]
[6] Guleria, P., Phulware, R., Agarwal, S., et al. (2018) Cytopathology of Solid Variant of Papillary Thyroid Carcinoma: Differential Diagnoses with Other Thyroid Tumors. Acta Cytologica, 62, 371-379. [Google Scholar] [CrossRef] [PubMed]
[7] Fulciniti, F., Barizzi, J., Trimboli, P., et al. (2019) Solid Papillary Thyroid Carcinoma with Hashimoto’s Thyroiditis: Description of a Further Case with Challenging Cytological Features. BMJ Case Reports, 12, e226153. [Google Scholar] [CrossRef] [PubMed]
[8] Ranabhat, S.K., Rijal, N.R., Dubey, M., et al. (2023) Morphological Study of Hashimoto Thyroiditis in Fine Needle Aspiration Cytology Specimens. International Journal of General Medi-cine, 16, 3127-3137. [Google Scholar] [CrossRef
[9] Kholova, I., Kalfert, D., Lintusaari, J., et al. (2021) Follicular Epithelial Dysplasia as Hashimoto Thyroiditis-Related Atypia: A Series of 91 Specimens. Endocrine Pathology, 32, 368-374. [Google Scholar] [CrossRef] [PubMed]
[10] Liu, H. and Lin, F. (2015) Application of Immunohistochemis-try in Thyroid Pathology. Archives of Pathology & Laboratory Medicine, 139, 67-82. [Google Scholar] [CrossRef
[11] Sadiq, Q., Sekhri, R., Dibaba, D.T., et al. (2021) HBME1 and CK19 Expression in Non-Invasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP) vs Other Follicular Patterned Thyroid Lesions. World Journal of Surgical Oncology, 19, Article No. 143. [Google Scholar] [CrossRef] [PubMed]
[12] 甲状腺细针穿刺细胞病理学诊断专家共识编写组, 中华医学会病理学分会细胞病理学组, 刘志艳, 等. 甲状腺细针穿刺细胞病理学诊断专家共识(2023版) [J]. 中华病理学杂志, 2023, 52(5): 441-446.