超声对继发性甲状旁腺功能亢进诊断价值研究进展

Progress of the Preoperative Diagnostic Val-ue of Ultrasound for Secondary Hyperparathyroidism

摘要: 继发性甲状旁腺功能亢进(secondary hyperparathyroidism, SHPT)已成为慢性肾脏病(Chronic Kid-ney Disease, CKD)的主要并发症之一，其发病机制复杂，随着病情发展，大量PTH释放入血作用于体内的靶器官后，会出现关节疼痛、贫血等并发症，严重影响生活质量和增加心血管死亡率，所以，甲状旁腺切除术对改善患者的预后十分重要，手术前常采用影像学方法对增生甲状旁腺的数量、大小及位置进行精准判断。鉴于此，本文就超声对继发性甲状旁腺功能亢进患者的术前诊断价值的相关研究进展做一综述。

Abstract: Secondary hyperparathyroidism (SHPT) has become one of the main complications of chronic kid-ney disease (CKD), and its pathogenesis is complex. With the progression of the disease, a substan-tial amount of parathyroid hormone (PTH) is released into the bloodstream and exerts its effects on target organs within the body, leading to joint pain, anemia, and other complications that signifi-cantly oint pain, anemia, and other complications that significantly impact quality of life and elevate cardiovascular mortality rates. Consequently, parathyroidectomy plays a crucial role in enhancing patient prognosis. Prior to surgery, imaging techniques are frequently employed to accurately as-sess the number, size, and location of hyperplastic parathyroid glands. In light of this context, this article provides a comprehensive review on the advancements made in utilizing ultrasonography for preoperative diagnosis of secondary hyperparathyroidism.