地板藤泡饮联合德谷门冬双胰岛素在2型糖尿病患者中的应用效果评价
Evaluation of the Effect of Ficus tikoua Bur Decoction Combined with Insulin Degludec/Insulin Aspart in Patients with Type 2 Diabetes
DOI: 10.12677/ns.2024.1312256, PDF,   
作者: 肖滕晖：铜仁职业技术学院附属医院综合内科，贵州 铜仁；彭 娇*：贵州航空职业技术学院现代服务学院，贵州 贵阳
关键词: 地板藤；德谷门冬胰岛素；2型糖尿病；Ficus tikoua Bur； Insulin Degludec/Insulin Aspart； Type 2 Diabetes
摘要: 目的：了解地板藤泡饮联合德谷门冬双胰岛素在2型糖尿病患者中的应用效果。方法：将铜仁市某二级医院60例2型糖尿病患者随机分组，观察组30例，对照组30例，对照组给予常规治疗方式，即德谷门冬双胰岛素配合基础治疗，观察组在对照组基础上，加用地板藤泡饮。结果：观察组在降低空腹血糖及餐后2h血糖方面效果优于对照组，差异具有统计学意义(P < 0.05)；两组患者达到控制目标的全日胰岛素用量相当，差异无统计学意义(P > 0.05)；观察组达到目标血糖时间更短，差异具有统计学意义(P < 0.05)。结论：地板藤泡饮联合德谷门冬双胰岛素在降低2型糖尿病患者空腹血糖及餐后2 h血糖方面优于单用德谷门冬双胰岛素，降糖效果更快；达到控制目标的全日胰岛素用量效果相当。
Abstract: Objective: To investigate the effect of Ficus tikoua Bur decoction combined with insulin degludec/insulin aspartn in patients with type 2 diabetes. Methods: Sixty patients with type 2 diabetes in a second-level hospital in Tongren were randomly divided into an observation group and a control group. The control group was given conventional treatment, that was insulin degludec/insulin aspart combined with basic treatment, and the observation group was given Ficus tikoua Bur decoction on the basis of the control group. Results: The observation group was better than the control group in reducing fasting blood sugar and 2-hour postprandial blood sugar, and the difference was statistically significant (P < 0.05); the full-day insulin doses for patients in the two groups to achieve the control target were similar, and there was no statistical significance (P > 0.05); the observation group took a shorter time to reach the target blood sugar, and the difference was statistically significant (P < 0.05). Conclusions: Ficus tikoua Bur decoction combined with insulin degludec/insulin aspart was better than insulin degludec/insulin aspart alone in lowering fasting blood sugar and 2-hour postprandial blood sugar in patients with type 2 diabetes, and the blood sugar lowering effect was faster; the full-day insulin dose was equivalent.
文章引用：肖滕晖, 彭娇. 地板藤泡饮联合德谷门冬双胰岛素在2型糖尿病患者中的应用效果评价[J]. 护理学, 2024, 13(12): 1800-1806. https://doi.org/10.12677/ns.2024.1312256

参考文献

[1] Leung, P.S. (2010) Current Research of the RAS in Diabetes Mellitus. In: Leung, P.S., Ed., The Renin-Angiotensin System: Current Research Progress in the Pancreas, Springer, 131-153. [Google Scholar] [CrossRef] [PubMed]
[2] Tremamunno, S., Tartaglione, L., Telesca, A., Rizzi, A., Felici, T., Mazzotta, F., et al. (2024) Insulin Pump Treatment Vs. Multiple Daily Insulin Injections in Patients with Poorly Controlled Type 2 Diabetes Mellitus: A Comparison of Cardiovascular Effects. Endocrine, 84, 128-135. [Google Scholar] [CrossRef] [PubMed]
[3] Thipsawat, S. (2023) Intervention for Prevention of Type 2 Diabetes Mellitus among Prediabetes: A Review of the Literature. SAGE Open Nursing, 9, 1709-1711. [Google Scholar] [CrossRef] [PubMed]
[4] Shrivastav, D., Dabla, P.K., Singh, D.D. and Mehta, V. (2023) Type 2 Diabetes Mellitus and Coronary Artery Stenosis: A Risk Pattern Association Study. Exploration of Medicine, 4, 336-342. [Google Scholar] [CrossRef] 
[5] 李元增, 赵济, 程炳铎, 等. 基于UPLC-QE-MS联合网络药理学研究地板藤治疗原发性痛经的作用机制[J]. 中国医院药学杂志, 2023, 43(23): 2630-2640.
[6] 张文平, 张晓平, 马大龙, 等. 民族药地板藤不同萃取部位体外抗病毒实验研究[J]. 中国现代中药, 2018, 20(3): 288-292+304.
[7] Wang, H., Zhang, K., Chen, X., Han, M., Lu, J. and Zhang, Y. (2022) In Vitro and in Vivo Evaluation of Antidiabetic Properties and Mechanisms of Ficus tikoua Bur. Nutrients, 14, Article No. 4413. [Google Scholar] [CrossRef] [PubMed]
[8] 中华医学会糖尿病学分会. 中国2型糖尿病防治指南(2020年版) [J]. 中华糖尿病杂志, 2021, 13(4): 315-409.
[9] Katabami, T., Eriksen, K.T., Yamamoto, Y. and Ishigaki, Y. (2021) Long-Term Safety and Clinical Outcomes with Insulin Degludec/Insulin Aspart Treatment in Japanese Patients with Diabetes: A Real-World, Prospective, Observational Study. Advances in Therapy, 39, 544-561. [Google Scholar] [CrossRef] [PubMed]
[10] Ritzel, R., Ghosh, S., Emral, R., Malek, R., Zeng, L., Mabunay, M.A., et al. (2023) Comparative Efficacy and Safety of Gla‐300 versus IDegAsp in Insulin-Naïve People with Type 2 Diabetes Mellitus Uncontrolled on Oral Anti‐Diabetics. Diabetes, Obesity and Metabolism, 25, 2495-2504. [Google Scholar] [CrossRef] [PubMed]
[11] 宋玮. 德谷门冬双胰岛素注射液治疗2型糖尿病的疗效[J]. 中国城乡企业卫生, 2024, 39(7): 116-118.
[12] 李燕祥, 刘永兰, 石文霞. 德谷门冬双胰岛素治疗口服降糖药控制不佳2型糖尿病的效果分析[J]. 系统医学, 2024, 9(8): 134-136+144.
[13] 吴冬波, 黄钰梅, 廖伟玲, 等. 德谷门冬双胰岛素治疗预混胰岛素控制不佳的2型糖尿病的临床效果[J]. 临床合理用药, 2024, 17(13): 13-16.
[14] 杨世波. 地板藤根的抗氧化和抑菌活性研究[J]. 云南民族大学学报: 自然科学版, 2013, 22(4): 235-238.
[15] Wei, S., Wu, W. and Ji, Z. (2012) New Antifungal Pyranoisoflavone from Ficus tikoua Bur. International Journal of Molecular Sciences, 13, 7375-7382. [Google Scholar] [CrossRef] [PubMed]
[16] Tian, M., Zhao, X., Wu, X., Hong, Y., Chen, Q., Liu, X., et al. (2020) Chemical Composition, Antibacterial and Cytotoxic Activities of the Essential Oil from Ficus tikoua Bur. Records of Natural Products, 14, 219-224. [Google Scholar] [CrossRef] 
[17] Xu, W., Li, S.-Z., et al. (2011) Chemical Constituents of Rhizomes of Ficus tikoua. Natural Product Research & Development, 23, 270-272.
[18] Zhong, X., et al. (2000) The Studied Survey on the Official of Moraceae ficus L. Chinese Traditional and Herbal Drugs, 31, 3-4.
[19] Ji, Y., Liu, D., Jin, Y., Zhao, J., Zhao, J., Li, H., et al. (2021) In Vitro and in Vivo Inhibitory Effect of Anthocyanin-Rich Bilberry Extract on Α-Glucosidase and Α-Amylase. LWT, 145, Article ID: 111484. [Google Scholar] [CrossRef] 
[20] 杨世波, 张润芝, 江志勇, 等. 地板藤根的化学成分研究[J]. 中成药, 2014, 36(3): 554-558.
[21] 田丽婷, 马龙, 堵年生. 齐墩果酸的药理作用研究概况[J]. 中国中药杂志, 2002(12): 9-11+26.

为你推荐