香苏通降散联合揿针疗法对IBS-D(脾胃虚弱证)的临床疗效观察

Observation of the Clinical Efficacy of Xiangsu Tong Jiangsan Combined with Press Needle Therapy on IBS-D (Spleen and Stomach Weakness Syndrome)

摘要: 目的：研究香苏通降散联合揿针疗法对IBS-D (脾胃虚弱证)的效果及血浆中血管活性肠肽(VIP)及P成分(SP)的改变，进一步探究其机制。方式：共纳入60例符合IBSD (腹泻型肠易激综合征)脾胃虚弱证入选标准的病人，随机数字表法分为香苏通降散联合揿针疗法(治疗组)和匹维溴铵片疗法组(对照组)，每组各30例，以4周为1星期，在治愈前后检查两组病人主要症状评估、血浆VIP及SP水平，并作出效果评估。结论：(1) 治疗前两组之间的病症总分数对比，无统计学差异，存在一致性；治疗后两组间的病症总分数对比，临床治疗组小于对照组(P < 0.05)，区别有统计价值。(2) 经过治疗两组病人的VIP和SP水平都得到了显著提高。经过4周的观察，两组之间的差别都很显著，这表明治疗组和对照组都取得了良好的结果。总的来看，这两组病人的情况都得到了显著地提高，而且治疗组的表现优于对照组。结论：香苏通降散联合揿针疗法能有效治疗腹泻型肠易激综合征(脾胃虚弱证)，显著改善患者症状及血清VIP和SP的水平，值得在临床推广运用。

Abstract: Objective: To study the effects of Xiangsu Tong Jiangsan combined with press needle therapy on IBS-D (spleen and stomach weakness syndrome) and the changes in plasma vascular active intestinal peptide (VIP) and P component (SP), further exploring its mechanism. Methods: A total of 60 patients meeting the criteria for IBS-D (Diarrhea Type Irritable Bowel Syndrome) with spleen and stomach weakness syndrome were included, randomly divided into Xiangsu Tong Jiangsan combined with press needle therapy (treatment group) and pivabromide tablets therapy group (control group), with 30 cases in each group, evaluated for main symptom assessment and plasma VIP and SP levels before and after 4 weeks of treatment, and assessed the effectiveness. Conclusion: (1) There was no statistically significant difference in the total symptom scores between the two groups before treatment, indicating consistency; after treatment, the total symptom scores of the clinical treatment group were significantly lower than those of the control group (P < 0.05), showing statistically significant differences. (2) After treatment, the VIP and SP levels of both groups of patients significantly increased. Over 4 weeks of observation, the differences between the two groups were highly significant, indicating that both the treatment group and the control group achieved good results. Overall, the conditions of both groups of patients significantly improved, with the treatment group performing better than the control group. Conclusion: Xiangsu Tong Jiangsan combined with press needle therapy can effectively treat diarrhea type irritable bowel syndrome (spleen and stomach weakness syndrome), significantly improving patient symptoms and serum VIP and SP levels, making it worthy of clinical promotion and application.