自噬在冠心病中的研究进展
Research Progress on Autophagy in Coronary Heart Disease
DOI: 10.12677/acm.2025.153793, PDF,   
作者: 刘 垚, 梁 玲, 杨锦文：西安医学院研究生工作部，陕西 西安；西安市第九医院心血管内科，陕西 西安；余 航, 王玉宁：西安医学院研究生工作部，陕西 西安；胡小菁*：西安市第九医院心血管内科，陕西 西安
关键词: 自噬；冠心病；心血管疾病；动脉粥样硬化；Autophagy； Coronary Heart Disease (CHD)； Cardiovascular Disease； Atherosclerosis
摘要: 冠心病是一种对人类健康构成重大威胁的心血管疾病，其发病机制错综复杂，尽管治疗方法多样，但仍面临许多亟待解决的挑战。近年来，自噬作为一种重要的细胞自我调节机制，在心血管疾病研究中逐渐受到关注。研究表明自噬与冠心病的发生发展密切相关，文章系统阐述了自噬的概念、机制以及在冠心病中的机制、挑战，旨在为冠心病的防治开辟新的视角和奠定理论基础。
Abstract: Coronary heart disease stands as a grave cardiovascular condition that presents a substantial risk to human health. Its pathogenesis is rather complex, and although there are various treatment methods, many challenges remain to be overcome. In recent years, autophagy, as an important cellular self-regulatory mechanism, has gradually attracted attention in the research of cardiovascular diseases. Research has indicated that there is a significant association between autophagy and the onset as well as progression of coronary heart disease. This article systematically elucidates the overview and mechanisms of autophagy, as well as its mechanisms and challenges in coronary heart disease, aiming to provide novel perspectives and establish a theoretical foundation for the prevention and treatment of coronary heart disease.
文章引用：刘垚, 梁玲, 杨锦文, 余航, 王玉宁, 胡小菁. 自噬在冠心病中的研究进展[J]. 临床医学进展, 2025, 15(3): 1695-1700. https://doi.org/10.12677/acm.2025.153793

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