泌尿系结石远期肾功能损伤因素研究进展

Progress in the Study of Factors of Impairment of Renal Function in the Distant Stage of Urinary Stones

摘要: 泌尿系结石对人体损害有机械损伤、梗阻、感染及引起恶性变等方面，其中，对人体泌尿系统可造成不同程度的损伤，尤其是急性肾损伤。年龄、结石病史、结石成分及代谢因素在泌尿系结石形成和发展的过程中，起着不同程度的成石促石作用，进而损伤肾功能。在诊疗手段愈发完备的时代背景下，无症状结石患者的诊出率提高，因此研究泌尿系结石影响肾功能下降机制，及早对早期结石病人采取干预措施保护肾功能，最大程度降低肾损害具有重大意义。

Abstract: Urologic stones damage the human body in terms of mechanical injury, obstruction, infection and causing malignant changes, among which, it can cause different degrees of damage to the human urinary system, especially acute kidney injury. Age, stone history, stone composition and metabolic factors in the formation and development of urinary stones, play a different degree of stone-forming and stone-promoting role, and then damage to kidney function. In an era of increasingly sophisticated diagnostic and therapeutic means, the diagnosis and detection rate of asymptomatic stone patients has increased, so it is of great significance to study the mechanism of urinary stones affecting the decline of renal function, and to take early interventions to protect renal function and minimize renal damage in early-stage stone patients.